A novel biotinylated suicide inhibitor for directed molecular evolution of lipolytic enzymes

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 3, 2000, Pages 507-513

  Deussen, H J ^a   Danielsen, S ^a   Breinholt, J ^a   Borchert, T V ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; BIOTIN; DISULFIDE; ENZYME INHIBITOR; ESTERASE; FUNCTIONAL GROUP; PHOSPHONIC ACID DERIVATIVE; SUCCINIMIDE DERIVATIVE; TRIACYLGLYCEROL LIPASE; TRIMETHYLSILYL DERIVATIVE;

AFFINITY LABELING; ARTICLE; BIOTINYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CONTROLLED STUDY; DIRECTED MOLECULAR EVOLUTION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBSTRATE; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; IMMUNOBLOTTING; LIPOLYSIS; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

AFFINITY LABELS; BIOTINYLATION; DIRECTED MOLECULAR EVOLUTION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOMAGNETIC SEPARATION; KINETICS; LIPASE; LIPOLYSIS; NITROPHENOLS; ORGANOPHOSPHORUS COMPOUNDS; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034005125     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00002-X     Document Type: Article

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