Distinct representations of eye gaze and identity in the distributed human neural system for face perception

Nature Neuroscience

Volumn 3, Issue 1, 2000, Pages 80-84

  Hoffman, Elizabeth A ^a   Haxby, James V ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ATTENTION; BRAIN REGION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEPTH PERCEPTION; FACIAL EXPRESSION; GAZE; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCIPITAL CORTEX; PRIORITY JOURNAL; VISION;

ADULT; BRAIN; BRAIN MAPPING; FACE; FEMALE; FIXATION, OCULAR; FORM PERCEPTION; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PHOTIC STIMULATION; REFERENCE VALUES; SPACE PERCEPTION;

EID: 0034004509     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/71152     Document Type: Article

References (46)

1. Damasio, A., Damasio, H. & Van Hoesen, G. Prosopagnosia: anatomic basis and behavioral mechanisms. Neurology 32, 331-341 (1982).
2. Farah, M. Is face recognition 'special'? Evidence from neuropsychology. Behav. Brain Res. 76, 181-189 (1996).
3. Sergent, J. & Signoret, J. Functional and anatomic decomposition of face processing: Evidence from prosopagnosia and PET study of normal subjects. Phil. Trans. R. Soc. Lond. B Biol. Sci. 335, 55-62 (1992).
4. Haxby, J. et al. The effect of face inversion on activity in human neural systems for face and object perception. Neuron 22, 189-199 (1999).
5. Kanwisher, N., Tong, F. & Nakayama, K. The effect of face inversion on the human fusiform face area. Cognition 68, 1-11 (1998).
6. Kanwisher, N., McDermott, J. & Chun, M. The fusiform face area: a module in human extrastriate cortex specialized for face perception. J. Neurosci. 17, 4302-4311 (1997).
7. McCarthy, G., Puce, A., Gore, J. & Allison, T. Face-specific processing in the human fusiform gyrus. J. Cog. Neurosci. 9, 605-610 (1997).
8. Halgren, K. et al. Location of human face-selective cortex with respect to retinotopic areas. Hum. Brain Mapp. 7, 29-37 (1999).
9. Puce, A., Allison, T., Bentin, S., Gore, J. & McCarthy, G. Temporal cortex activation in humans viewing eye and mouth movements. J. Neurosci. 18, 2188-2199 (1998).
10. Wicker, B., Michel, F., Henaff, M.-A. & Decety, J. Brain regions involved in the perception of gaze: A PET study. Neuroimage 8, 221-227 (1998).
11. Hasselmo, M., Rolls, E. & Baylis, G. The role of expression and identity in the face-selective responses of neurons in the temporal visual cortex of the monkey. Behav. Brain Res. 32, 203-218 (1989).
12. Perrett, D. et al. Neurones responsive to faces in the temporal cortex: studies of functional organization, sensitivity to identity and relation to perception. Hum. Neurobiol. 3, 197-208 (1984).
13. Perrett, D. et al. Visual cells in the temporal cortex sensitive to face view and gaze direction. Proc. R. Soc. Lond. 223, 293-317 (1985).
14. Perrett, D. et al. Social signals analyzed at the single cell level: someone is looking at me, something touched me, something moved. Int. J. Comp. Psychol. 4, 25-55 (1990).
15. Friesen, C. & Kingstone, A. The eyes have it! Reflexive orienting is triggered by nonpredictive gaze. Psychol. Bull. Rev. 5, 490-495 (1998).
16. Corbetta, M., Shulman, G., Miezin, F. & Peterson, S. Superior parietal cortex activation during spatial attention shifts and visual feature conjunction. Science 270, 802-805 (1995).
17. Corbetta, M. Frontoparietal cortical networks for directing attention and the eye to visual locations: Identical, independent, or overlapping neural systems? Proc. Natl. Acad. Sci. USA 95, 831-838 (1998).
18. Nobre, A. et al. Functional localization of the system for visuospatial attention using positron emission tomography. Brain 120, 515-533 (1997).
19. Emery, N., Lorincz, E., Perrett, D., Oram, M. & Baker, C. Gaze following and joint attention in rhesus monkeys (Macaca mulatta). J. Comp. Psychol. 111, 286-293 (1997).
20. Hains, S. & Muir, D. Infant sensitivity to adult eye direction. Child Dev. 67, 1940-1951 (1996).
21. Hood, B., Willen, J. & Driver, J. Adult's eyes trigger shifts of visual attention in human infants. Psychol. Sci. 9, 131-134 (1998).
22. Vecera, S. & Johnson, M. Gaze detection and the cortical processing of faces: Evidence from infants and adults. Vis. Cognit. 2, 59-87 (1995).
23. Tomasello, M., Call, J. & Hare, B. Five primate species follow the visual gaze of conspecifics. Anim. Behav. 55, 1063-1069 (1998).
24. Kanwisher, N., Stanley, D. & Harris, A. The fusiform face area is selective for faces not animals. Neuroreport 10, 183-187 (1999).
25. Haxby, J. et al. The functional organization of human extrastriate cortex: A PET-rCBF study of selective attention to faces and locations. J. Neurosci. 14, 6336-6353 (1994).
26. Tranel, D., Damasio, A. & Damasio, H. Intact recognition of facial expression, gender, and age in patients with impaired recognition of face identity. Neurology 38, 690-696 (1988).
27. Sergent, J., Ohta, S. & MacDonald, B. Functional neuroanatomy of face and object processing. A positron emission tomography study. Brain 115, 15-36 (1992).
28. Sergent, J., Ohta, S., MacDonald, B. & Zuck, E. Segregated processing of facial identity and emotion in the human brain: a PET study. Vis. Cognit. 1, 349-369 (1994).
29. Aguirre, G., Singh, R. & D'Esposito, M. Stimulus inversion and the responses of face and object-sensitive cortical areas. Neuroreport 10, 189-194 (1999).
30. Puce, A., Smith, A. & Allison, T. ERPs evoked by viewing facial movements. Cognit. Neuropsychol. (in press).
31. McCarthy, G., Puce, A., Belger, A. & Allison, T. Electrophysiological studies of human face perception. II. Response properties of face-specific potentials generated in occipitotemporal cortex. Cereb. Cortex 9, 431-444 (1999).
32. Campbell, R., Heywood, C., Cowey, A., Regard, M. & Landis, T. Sensitivity to eye gaze in prosopagnosia patients and monkeys with superior temporal sulcus ablation. Neuropsychologia 28, 1123-1142 (1990).
33. Heywood, C. & Cowey, A. The role of the 'face-cell' area in the discrimination and recognition of faces by monkeys. Phil. Trans. R. Soc. Lond. B Biol. Sci. 335, 31-38 (1992).
34. Phillips, M. et al. Neural responses to facial and vocal expressions of fear and disgust. Proc. R. Soc. Lond. B Biol. Sci. 265, 1809-1817 (1998).
35. Calvert, G. et al. Activation of auditory cortex during silent lipreading. Science 276, 593-596 (1997).
36. Breiter, H. et al. Response and habituation of the human amygdala during visual processing of facial expression. Neuron 17, 875-887 (1996).
37. Morris, J. et al. A differential neural response in the human amygdala to fearful and happy facial expressions. Nature 383, 812-815 (1996).
38. Harries, M. & Perrett, D. Visual processing of faces in temporal cortex: Physiological evidence for a modular organization and possible anatomical coordinates. J. Cogn. Neurosci. 3, 9-24 (1991).
39. Kawashima, R. et al. The human amygdala plays an important role in gaze monitoring: A PET study. Brain 122, 779-783 (1999).
40. Gale, A., Kingsley, E., Brookes, S. & Smith, D. Cortical arousal and social intimacy in the human female under different conditions of eye contact. Behav. Proc. 3, 271-275 (1978).
41. Van Hooff, J. A. Facial expressions in higher primates. Symp. Zool. Soc. Lond. 8, 97-125 (1962).
42. Mendelson, M., Haith, M. & Goldman-Rakic, P. Face scanning and responsiveness to social cues in infant rhesus monkeys. Dev. Psychol. 18, 222-228 (1982).
43. Perrett, D. & Mistlin, A. in Comparative Perception Vol. 2 (eds. Stebbins, W. & Berkley, M.) 187-215 (Wiley, New York, 1990).
44. Perrett, D., & Emery, N. Understanding the intentions of others from visual signals: neurophysiological evidence. Curr. Psychol. Cogn. 13, 683-694 (1994).
45. Talairach, J. & Tournoux, P. Co-Planar Stereotaxic Atlas of the Human Brain (Thieme, Stuttgart, 1988).
46. Friston, K. et al. Statistical parametric mapping in functional imaging: a general linear approach. Hum. Brain Mapp. 2, 189-210 (1995).