Differential contribution of the conserved tyrosine residues to activity and structural stability of Ophiophagus hannah α-neurotoxins

Journal of Peptide Research

Volumn 55, Issue 3, 2000, Pages 240-245

  Chang, Long sen ^a   Chang, C C ^b   Lin, S R ^b  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

neurotoxin; Lethality; Modification of tyrosine residue; nAchR binding activity; Structural stability

Indexed keywords

NEUROTOXIN; NICOTINIC RECEPTOR; PRECIPITIN; TETRANITROMETHANE; TYROSINE;

ARTICLE; BINDING KINETICS; CONTROLLED STUDY; LETHALITY; NEUROTOXICITY; NITRATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STABILITY; RECEPTOR BINDING; SNAKE; STRUCTURE ACTIVITY RELATION; TOXIN ANALYSIS; TOXIN STRUCTURE;

CIRCULAR DICHROISM; COBRA VENOMS; IMMUNODIFFUSION; NEUROTOXINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, NICOTINIC; TETRANITROMETHANE; TYROSINE;

OPHIOPHAGUS HANNAH; SERPENTES; VERTEBRATA;

EID: 0034003507     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2000.00176.x     Document Type: Article

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