Inhibitors of protein phosphorylation including the retinoblastoma protein induce germination of Candida albicans

Medical Mycology

Volumn 38, Issue 1, 2000, Pages 41-45

  Cho, T ^a   Hamatake, H ^a   Hagihara, Y ^a   Kaminishi, H ^a  

^a FUKUOKA DENTAL COLLEGE   (Japan)

Author keywords

Candida albicans; Dephosphorylation; Differentiation; Proliferation

Indexed keywords

FORSKOLIN; OKADAIC ACID; PROTEIN INHIBITOR; SPHINGOSINE;

ANIMAL CELL; ARTICLE; CANDIDA ALBICANS; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DEPHOSPHORYLATION; GERMINATION; GROWTH INHIBITION; MYCELIUM; NONHUMAN; RETINOBLASTOMA; YEAST;

ANIMALIA; CANDIDA ALBICANS; MAMMALIA;

EID: 0034002399     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1080/714030875     Document Type: Article

References (34)

1. Odds FC. Candida and Candidosis, 2nd edn. London: Bailliere Tindall, 1988.
2. Cutler JE. Putative virulence factors of Candida albicans. Annu Rev Microbiol 1991; 45: 187-218.
3. Calderone RA. Molecular pathogenesis of fungal infections. Trends Microbiol 1994; 2: 461-463.
4. Odds FC. Candida species and virulence. ASM News 1994; 60: 313-318.
5. Hagihara Y, Cho T, Kuroki A, et al. Aging and germ tube formation in Candida albicans. J Fukuoka Dent Col 1988; 15: 63-71.
6. Cho T, Hamatake H, Kaminishi H, et al. Starvation and germ tube formation in the exponential phase Candida albicans. J Fukuoka Dent Col 1989; 16: 510-521.
7. Cho T, Hamatake Y, Kaminishi H, Watanabe K. The relationship between the glucose uptake system and growth cessation in Candida albicans. J Med Vet Mycol 1994; 32: 461-466.
8. Cho T, Hagihara H, Kaminishi H, Hagihara Y, Watanabe K. The relationship between cyclic adenosine 3′,5′-monophosphate and morphology in exponential phase Candida albicans. J Med Vet Mycol 1992; 30: 35-42.
9. Cho T. Hirota T, Hamatake H, et al. Cell cycle and dimorphism in Candida albicans. In: Suzuki S, Suzuki M, eds. Fungal cells in Biodefense Mechanism. Tokyo, Japan: Saikonn Publishing, 1996: 41-44.
10. De Luca A, Esposite V, Baldi A, Giordano A. The retinoblastoma gene family and its role in proliferation, differentiation and development. Histol Histopathol 1996; 11: 1029-1034.
11. Hollingsworth RE, Chen PL, Lee WH. Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein. Cuir Opin Cell Biol 1993; 5: 194-200.
12. Riley DJ, Lee EY, Lee WH. The retinoblastoma protein: more than a tumor suppressor. Annu Rev Cell Biol 1994; 10: 1-29.
13. Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 1995; 8: 323-330.
14. Chen PL, Riley DJ, Chen Y, Lee WH. Retinoblastoma protein positively regulated terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev 1996; 10: 2794-2804.
15. Michell LH, Soll DR. Commitment to germ tube or bud formation during release from stationary phase in Candida albicans. Exper Cell Res 1979; 120: 167-179.
16. Pollack JH, Hashimoto T. The role of glucose in the pH regulation of germ-tube formation in Candida albicans. J Gen Microbiol 1987; 133: 415-424.
17. Buchkovich K, Duffy LA, Harlow E. The retinoblastoma protein is phosphorylated during specific phase of the cell cycle. Cell 1989; 58: 1097-1105.
18. Chen PL, Scully P, Shew JY, Wang JY, Lee WH. Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell 1989; 58: 1193-1198.
19. Xie Q, Sanz-Burgos AP, Hannon GJ, Gutierrez C. Plant cells contain a novel member of the retinoblastoma family of growth regulatory proteins. EMBO J 1996; 15: 4900-4908.
20. Seamon KB, Daly JW. Forskolin: a unique diterpene activator of cyclic AMP-generation system. J Cyclic Nucleotide Res 1981; 7: 201-224.
21. Blomhoff HK, Smeland EB, Beiske K, et al. Cyclic AMP-mediated suppression of normal and neoplastic B cell proliferation is associated with regulation of myc and Ha-ras protooncogenes. J Cell Physiol 1987; 131: 426-433.
22. Christoffersen J, Smeland EB, Stokke T, et al. Retinoblastoma protein is rapidly dephosphorylated by elevated cyclic adenosine monophosphate levels in human B-lymphoid cells. Cancer Res 1994; 54: 2245-2250.
23. Ishida Y, Furukawa Y, Decaprio JA, Saito M, Griffin JD. Treatment of myeloid leukemic cells with the phosphatase inhibitor okadaic acid induces cell cycle arrest at either G1/S or G2/M depending on dose. J Cell Physiol 1992; 150: 484-492.
24. Casillas AM, Amaral K. Chegini-Farahani S, Neil AE. Okadaic acid activates p42 mitogen-activated protein kinase (MAP kinase; ERK-2) in B lymphocytes but inhibits rather than augments cellular proliferation; contrast with phorbol 12-myristate 13-acetate. Biochem J 1993; 290: 545-550.
25. Nishina Y, Sumi T, Iwai SA, Nishimune Y. Effects of protein phosphatase inhibition by okadaic acid on the differentiation of F9 embryonal carcinoma cell. Exp Cell Res 1995; 217: 288-293.
26. Cohen P, Holmes CFB, Tsukitani Y. Okadaic acid: a new probe for the study of cellular regulation. Trends Biochem Sci 1990; 15: 98-102.
27. Chao R, Khan W, Hannun YA. Retinoblastoma protein dephosphrylation induced by D-erythro-sphingosine. J Biol Chem 1992; 267: 23459-23462.
28. Pushkareva M, Chao R, Bielawska A, et al. Stereoselectivity of induction of the retinoblastoma gene product (pRb) dephosphorylation by D-erythro-sphingosine supports a role for pRb in growth suppression by sphingosine. Biochemistry 1995; 34: 1885-1892.
29. Paranjape V, Roy BG, Datta A. Involvemert of calcium, calmodulin and protein phosphorylation in morphogenesis of Candida albicans. J Gen Microbiol 1990; 136: 2149-2154.
30. Sabie FT, Gadd GM. Effect of nucleosides and nucleotides and the relationship between cellular adenosire 3′:5′-cyclic monophosphate (cyclic AMP) and germ tube formation in Candida albicans. Mycopathologia 1992; 119: 147-156.
31. Niimi M. Dibutyryl cyclic AMP-enhanced germ tube formation in exponentially growing Candida albicans cells. Fungal Genet Biol 1996; 20: 79-83.
32. Blacketer MJ, Koehler CM. Coats SG, Myers AM, Madaule P. Regulation of dimorphism in Saccharomyces cerevisiae; involvement of the novel protein kinase homolog Elm 1 p and protein phosphatase 2A. Mol Cell Biol 1993; 13: 5567-5581.
33. Blacketer MJ, Madaule P, Myers AM. Mutational analysis of morphologic differentiation in Saccharomyces cerevisiae. Genetics 1995; 140: 1259-1275.
34. Csank C, Makris C, Meloche S, et al. Derepressed hyphal growth and redued virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans. Mol Biol Cell 1997; 8: 2539-2551.