Hyperglycaemia-induced subcellular redistribution of GLUT1 glucose transporters in cultured human term placental trophoblast cells

Diabetologia

Volumn 43, Issue 2, 2000, Pages 173-180

  Hahn, T ^a   Hahn, D ^a   Blaschitz, A ^a   Korgun, E T ^a   Desoye, G ^a   Dohr, G ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

Diabetes; Electron microscopy; Glucose; GLUT1; Hyperglycaemia; Pla centa; Pregnancy; Translocation; Transport; Trophoblast

Indexed keywords

ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; CHROMOSOME TRANSLOCATION; DOWN REGULATION; ELECTRON MICROSCOPY; GLUCOSE METABOLISM; HEXOSE TRANSPORT; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOBLOTTING; IMMUNOGOLD STAINING; PRIORITY JOURNAL; TROPHOBLAST;

CELL SURVIVAL; CELLS, CULTURED; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HUMANS; HYPERGLYCEMIA; KINETICS; MICROVILLI; MONOSACCHARIDE TRANSPORT PROTEINS; PLACENTA; PREGNANCY; SUBCELLULAR FRACTIONS; TROPHOBLASTS;

EID: 0034002141     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050026     Document Type: Article

References (50)

1. 1. Kalhan SC, D'Angelo LJ, Savin SM, Adam PAJ (1979) Glucose production in pregnant women at term gestation. J Clin Invest 63: 388-394
2. 2. Sibley CP, Boyd RDH (1992) Mechanisms of transfer across the human placenta. In: Polin RA, Fox WW (eds) Fetal and neonatal physiology, vol 1. Saunders, Philadelphia, pp 62-74
3. 3. Stein WD (1967) The movement of molecules across cell membranes. Academic Press, New York
4. 4. Mueckler M (1994) Facilitative glucose transporters. Eur J Biochem 219: 713-725
5. 5. Waddell ID, Scott HM, Grant A, Burchell A (1991) Identification and characterization of a hepatic microsomal glucose transport protein. Biochem J 275: 363-367
6. 6. Hahn T, Hartmann M, Blaschitz A et al. (1995) Localization of the high affinity facilitative glucose transporter protein GLUT1 in the human, marmoset-monkey (Callithrix jacchus) and rat placentae at different developmental stages. Cell Tissue Res 280: 49-57
7. 7. Schneider H (1996) Ontogenic changes in the nutritive function of the placenta. Placenta 17: 15-26
8. 8. Hahn T, Barth S, Graf R et al. (1999) Placental glucose transporter expression is regulated by glucocorticoids. J Clin Endocrinol Metab 84: 1445-1452
9. 9. Testar X, Lasuncion MA, Chieri R, Herrera E (1985) Effects of exogenous insulin on placental transfer of maternal glucose to the rat fetus. Diabetologia 28: 743-748
10. 10. Challier JC, Hauguel S, Desmaizieres V (1986) Effect of insulin on glucose uptake and metabolism in the human placenta. J Clin Endocrinol Metab 62: 803-807
11. 11. Hahn T, Barth S, Weiss U, Mosgoeller W, Desoye G (1998) Sustained hyperglycaemia in vitro downregulates the GLUT1 glucose transport system of cultured human term placental trophoblast. A mechanism to protect fetal development? FASEB J 12: 1221-1231
12. 12. Illsley NP, Sellers MC, Wright RL (1998) Glycaemic regulation of glucose transporter expression and activity in the human placenta. Placenta 19: 517-524
13. 13. Hahn T, Barth S, Hofmann W, Reich O, Lang I, Desoye G (1998) Hyperglycaemia regulates the glucose transport system of clonal choriocarcinoma cells in vitro. A potential molecular mechanism contributing to the adjunct effect of glucose in tumor therapy. Int J Cancer 78: 353-360
14. 14. Schmon B, Hartmann M, Jones CJ, Desoye G (1991) Insulin and glucose do not affect the glycogen content in isolated and cultured cells of human term placentae. J Clin Endocrinol Metab 73: 888-893
15. 15. Shorter SC, Starkey PM, Ferry BL, Clover LM, Sargent IL, Redman CWG (1993) Antigenic heterogeneity of human cytotrophoblast and evidence for the transient expression of MHC class I antigens distinct from HLA-G. Placenta 14: 571-582
16. 16. Beham A, Denk H, Desoye G (1988) The distribution of intermediate filament proteins, actin and desmoplakins in human placental tissue as revealed by polyclonal and monoclonal antibodies. Placenta 9: 479-492
17. 17. Lang I, Hartmann M, Blaschitz A, Dohr G, Skofitsch G, Desoye G (1993) Immunohistochemical evidence for the heterogeneity of maternal and fetal vascular endothelial cells in human full-term placenta. Cell Tissue Res 274: 211-218
18. 18. Birnbaum MJ, Haspel HC, Rosen OM (1986) Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein. Proc Natl Acad Sci USA 83: 5784-5788
19. 19. Haspel HC, Rosenfeld MG, Rosen OM (1988) Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein. J Biol Chem 263: 398-403
20. 20. Haney PM, Slot JW, Piper RC, James DE, Mueckler M (1991) Intracellular targeting of the insulin-regulatable glucose transporter (GLUT4) is isoform specific and independent of cell type. J Cell Biol 114: 689-699
21. 21. Harris DS, Slot JW, Geuze HJ, James DE (1992) Polarized distribution of glucose transporter isoforms in Caco-2 cells. Proc Natl Acad Sci USA 89: 7556-7560
22. 22. Blok J, Gibbs EM, Lienhard GE, Slot JW, Geuze HJ (1988) Insulin-induced translocation of glucose transporters from post-Golgi compartments to the plasma membrane of 3T3-L1 adipocytes. J Cell Biol 106: 69-76
23. 23. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275
24. 24. Buchanan TA, Kjos SL (1994) Diabetes and pregnancy. Curr Ther Endocrinol Metab 5: 278-283
25. 25. Eriksson UJ (1996) Lifelong consequences of metabolic adaptations in utero? Diabetologia 39: 1123-1125
26. 26. Freinkel N (1980) The Banting Lecture 1980: of pregnancy and progeny. Diabetes 29: 1023-1035
27. 27. Desoye G, Shafrir E (1994) Placental metabolism and its regulation in health and diabetes. Mol Aspects Med 15: 505-682
28. 28. Das UG, Sadiq HF, Soares MJ, Hay WW Jr, Devaskar SU (1998) Time-dependent physiological regulation of rodent and ovine placental glucose transporter (GLUT-1) protein. Am J Physiol 274:R339-R347
29. 29. Benirschke K, Kaufmann P (1995) Pathology of the human placenta. 3rd edn. Springer, Berlin Heidelberg New York
30. 30. Cervar M, Blaschitz A, Dohr G, Desoye G (1999) Paracrine regulation of distinct trophoblast functions in vitro by placental macrophages. Cell Tissue Res 295: 297-305
31. 31. Haspel HC, Birnbaum MJ, Wilk EW, Rosen EM (1985) Biosynthetic precursors and in vitro translation products of the glucose transporter of human hepatocarcinoma cells, human fibroblasts, and murine preadipocytes. J Biol Chem 260: 7219-7225
32. 32. Boileau P, Mrejen C, Girard J, Hauguel-de Mouzon S (1995) Overexpression of GLUT3 placental glucose transporter in diabetic rats. J Clin Invest 96: 309-317
33. 33. Barros LF, Yudilevich DL, Jarvis SM, Beaumont N, Baldwin SA (1995) Quantitation and immunolocalization of glucose transporters in the human placenta. Placenta 16: 623-633
34. 34. Malide D, Cushman SW (1997) Morphological effects of wortmannin on the endosomal system and GLUT4-containing compartments in rat adipose cells. J Cell Sci 110: 2795-2806
35. 35. Slot JW, Geuze HJ, Gigengack S, Lienhard GE, James DE (1991) Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat. J Cell Biol 113: 123-135
36. 36. Guillet-Deniau I, Leturque A, Girard J (1994) Expression and cellular localization of glucose transporters (GLUT1, GLUT3, GLUT4) during differentiation of myogenic cells isolated from rat foetuses. J Cell Sci 107: 487-496
37. 37. Kozka IJ, Clark AE, Reckless JP, Cushman SW, Gould GW, Holman GD (1995) The effects of insulin on the level and activity of the GLUT4 present in human adipose cells. Diabetologia 38: 661-666
38. 38. Zierath JR, He L, Guma A, Odegoard-Wahlstrom E, Klip A, Wallberg-Henriksson H (1996) Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM. Diabetologia 39: 1180-1189
39. 39. Zorzano A, Sevilla L, Camps M et al. (1997) Regulation of glucose transport, and glucose transporters expression and trafficking in the heart: studies in cardiac myocytes. Am J Cardiol 80: 65A-76A
40. 40. Galante P, Maerker E, Scholz R et al. (1994) Insulin-induced translocation of GLUT 4 in skeletal muscle of insulin-resistant Zucker rats. Diabetologia 37: 3-9
41. 41. Zorzano A, Wilkinson W, Kotliar N et al. (1989) Insulin-regulated glucose uptake in rat adipocytes is mediated by two transporter isoforms present in at least two vesicle populations. J Biol Chem 264: 12358-12363
42. 42. Clancy BM, Czech MP (1990) Hexose transport stimulation and membrane redistribution of glucose transporter isoforms in response to cholera toxin, dibutyryl cyclic AMP, and insulin in 3T3-L1 adipocytes. J Biol Chem 265: 12434-12443
43. 43. Klip A, Ramlal T, Bilan PJ, Marette A, Liu Z, Mitsumoto Y (1993) What signals are involved in the stimulation of glucose transport by insulin in muscle cells? Cell Signal 5: 519-529
44. 44. Holman GD, Cushman SW (1994) Subcellular localization and trafficking of the GLUT4 glucose transporter isoform in insulin-responsive cells. Bioessays 16: 753-759
45. 45. Rea S, James DE (1997) Moving GLUT4: the biogenesis and trafficking of GLUT4 storage vesicles. Diabetes 46: 1667-1677
46. 46. Greco-Perotto R, Wertheimer E, Jeanrenaud B, Cerasi E, Sasson S (1992) Glucose regulates its transport in L8 myocytes by modulating cellular trafficking of the transporter GLUT-1. Biochem J 286: 157-163
47. 47. Piper RC, Hess LJ, James DE (1991) Differential sorting of two glucose transporters expressed in nsulin-sensitive cells. Am J Physiol 260: C570-C580
48. 48. Asano T, Takata K, Katagiri H et al. (1992) Domains responsible for the differential targeting of glucose transporter isoforms. J Biol Chem 267: 19636-19641
49. 49. Shibasaki Y, Asano T, Lin JL et al. (1992) Two glucose transporter isoforms are sorted differentially and are expressed in distinct cellular compartments. Biochem J 281: 829-834
50. 50. Takata K, Kasahara M, Oka Y, Hirano H (1993) Mammalian sugar transporters: Their localization and link to cellular functions. Acta Histochem Cytochem 26: 165-178