Loss of heterozygosity on chromosome 17q in epithelial ovarian tumors: Association with carcinomas with serous differentiation

International Journal of Gynecological Pathology

Volumn 19, Issue 2, 2000, Pages 152-157

  Garcia, Arnald ^b   Bussaglia, Elena ^b   Machin, Pilar ^b   Matias Guiu, Xavier ^a   Prat, Jaime ^b  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b NONE

Author keywords

17q; BRCA 1; Loss of heterozygosity; Mixed endometrioid serous carcinomas; Ovarian tumors; Serous carcinomas; Sporadic ovarian cancers

Indexed keywords

DNA;

ARTICLE; CARCINOGENESIS; CHROMOSOME 17Q; DNA DETERMINATION; GENE AMPLIFICATION; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; OVARY CARCINOMA; OVARY TUMOR; PRIORITY JOURNAL;

EID: 0034001772     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004347-200004000-00009     Document Type: Article

References (35)

1. Russell SEH, Hickey GI, Lowry WS, White P, Atkinson RJ. Allele loss from chromosome 17 in ovarian cancer. Oncogene 1990;5: 1581-3.
2. Eccles DM, Cranston G, Steel CM, Nakamura Y, Leonard RCF. Allele losses on chromosome 17 in human epithelial ovarian carcinoma. Oncogene 1990;5:1599-1601.
3. Foulkes W, Black D, Solomon E, Trowsdale J. Allele loss on chromosome 17q in sporadic ovarian cancer. Lancet 1991;338: 444-5.
4. Sato T, Saito H, Morita R, Koi S, Lee JH, Nakamura Y. Allelotype of human ovarian cancer. Cancer Res 1991;51:5118-22.
5. Lee JH, Kavanagh JJ, Wildrick DM, Wharton JT, Blick M. Frequent loss of heterozygosity on chromosomes 6q, 11 and 17 in human ovarian carcinomas. Cancer Res 1990;50:2724-8.
6. Phillips N, Ziegler M, Saha B, Xynos F. Allelic loss on chromosome 17 in human ovarian cancer. Int J Cancer 1993;54:85-91.
7. Dodson MK, Hartmann LC, Cliby WA. Comparison of loss of heterozygosity patterns in invasive low-grade and high-grade epithelial ovarian carcinomas. Cancer Res 1993;53:4456-60.
8. Saito H, Inazawa J, Saito S, et al. Detailed deletion mapping of chromosome 17q in ovarian and breast cancers: 2-cM region in 17q21-3 often and commonly deleted in tumors. Cancer Res 1993; 53:3382-5.
9. Jacobs IJ, Smith SA, Wiseman RW, et al. A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus. Cancer Res 1993;53:1218-21.
10. Pieretti M, Powell D, Gallion HH, Caze E, Conway PS, Turker MS. Genetic alterations on chromosome 17 distinguish types of epithelial ovarian tumors. Hum Pathol 1995;26:393-7.
11. Cornelis RS, Neuhausen SL, Johansson O, et al. High allele loss rates at 17q 12-q21 in breast and ovarian tumors from BRCA-1-linked families. Genes Chromosomes Cancer 1995;13:203-10.
12. Miki Y, Swesen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA-1. Science 1994;266:66-71.
13. Friedman LS, Ostermeyer EA, Szabo C, Dowd P, Lynch ED, Rowell SE, King MC. Confirmation of BRCA-1 by analysis of germ-line mutations linked to breast and ovarian cancer in ten families. Nat Genet 1994; 8:399-404.
14. Shattuck-Eidens D, McClure M, Simard J, et al. A collaborative survey of 80 mutations in the BRCA-1 breast and ovarian cancer susceptibility gene. JAMA 1995;273:535-41.
15. Castilla LH, Couch FJ, Endos MR, et al. Mutations in the BRCA-1 gene in families with early breast and ovarian cancer. Nat Genet 1994;8:387-91.
16. Takahashi H, Behbakht K, McGovern PE, et al. Mutation analysis of the BRCA-1 gene in ovarian cancers. Cancer Res 1995;55: 2998-3002.
17. Futreal PA, Liu Q, Shattuck-Eidens D, et al. BRCA-1 mutations in primary breast and ovarian carcinomas. Science 1994;266:120-2.
18. Hosking L, Trowsdale J, Nicolai H, et al. A somatic BRCA-1 mutation in an ovarian tumor. Nat Genet 1995;9:343-4.
19. Merajner SD, Pham TM, Caduff RF, et al. Somatic mutations in the BRCA-1 gene in sporadic ovarian tumors. Nat Genet 1995;9: 439-40.
20. Rubin SC, Benjamin I, Behbakht K, et al. Clinical and pathological features of ovarian cancer in women with germ-line mutations of BRCA-1. N Engl J Med 1996;335:1413-6.
21. Dobrovic A, Simpfendorfer D. Methylation of the BRCA-1 gene in sporadic breast cancer. Cancer Res 1997;57:3347-50.
22. Mancini DN, Rodenhiser DI, Ainsworth PJ, O'Malley FP, Singh SM, Xing W, Archer TK. CpG methylation within the 5′ regulatory region of the BRCA-1 gene is tumor specific and includes a putative CREB binding site. Oncogene 1998;16:1161-9.
23. Rice JC, Massey-Brown KS, Futscher BW. Aberrant methylation of the BRCA-1 CpG island promoter is associated with decreased BRCA-1 mRNA in sporadic breast cancer cells. Oncogene 1998; 17:1807-12.
24. Johannsson OT, Idvall I, Anderson C. Tumor biological features of BRCA-1-induced breast and ovarian cancer. Eur J Cancer 1997; 33:362-71.
25. Marcus JN, Watson P, Page DL. BRCA2 and BRCA1 breast cancer phenotypes [Abstract]. Lab Invest 1997;76:110.
26. Karp SE, Tonin PN, Begin LR. Influence of BRCA1 mutations on nuclear grade and estrogen receptor status of breast carcinoma in Ashkenazi Jewish women. Cancer 1997;80:435-41.
27. Marcus JN, Page DL, Watson P. BRCA-1 and BRCA-2 hereditary breast carcinoma phenotypes. Cancer 1997;80:543-56.
28. Marcus JN, Watson P, Page DL. Hereditary breast-cancer-pathobiology, prognosis, and BRCA-1 and BRCA-2 gene linkage. Cancer 1996;77:697-709.
29. Powell DE, Puls LE, van Nagell JR. Current concepts in epithelial ovarian tumors: does benign to malignant transformation occur? Hum Pathol 1992;23:846-7.
30. Puls LE, Powell DE, De Priest PD, Gallion HH, Hunter JE, Kryscio RJ. Transition from benign to malignant epithelium in mucinous and serous ovarian cystadenocarcinoma. Gynecol Oncol 1992;47:53-7.
31. Tornos C, Silva EG, Khorana SM, Burke TW. High-stage endometrioid carcinoma of the ovary: prognostic significance of pure versus mixed histologic types. Am J Surg Pathol 1994;18:687-93.
32. Obata K, Morland SJ, Watson RH, Hitchcock A. Chenevix-Trench G, Thomas EJ, Campbell IG. Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors. Cancer Res 1998;58:2095-7.
33. Palacios J, Gamallo C. Mutations in the beta-catenin gene (CTNNB1) in endometrioid ovarian carcinomas. Cancer Res 1998; 58:1344-7.
34. Pieretti M, Turker MS. Mutation, ageing and ovarian cancer. Lancet 1997;349:700-1.
35. Fanthalla MF. Incessant ovulation: a factor in ovarian neoplasia? Lancet 1971;ii:163.