Increased cerebral blood flow in MELAS shown by Tc-99m HMPAO brain SPECT

Neuroradiology

Volumn 42, Issue 1, 2000, Pages 26-29

  Peng, N J ^b   Liu, R S ^a   Li, J Y ^b   Tsay, D G ^b   Kong, K W ^b   Kwok, C G ^c   Strauss, H W ^c  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

MELAS; Single photon emission computed tomography Cerebral blood flow

Indexed keywords

ANTICONVULSIVE AGENT; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; LACTIC ACID;

ADULT; ARTICLE; BLOOD PH; BRAIN BLOOD FLOW; BRAIN DISEASE; CASE REPORT; FEMALE; FOLLOW UP; GINGIVITIS; HUMAN; HUMAN TISSUE; LACTIC ACIDOSIS; MALE; MITOCHONDRIAL MYOPATHY; PRIORITY JOURNAL; SIBLING; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STROKE;

ADULT; BRAIN; CEREBRAL CORTEX; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MELAS SYNDROME; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M EXAMETAZIME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0034000525     PISSN: 00283940     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002340050005     Document Type: Article

References (11)

1. Lassen NA (1966) The luxury perfusion syndrome and its possible relation to acute metabolic acidosis localised within the brain. Lancet ii: 1113-1115
2. Yarnell P, Burdick D, Sanders B (1974) The "hot stroke" a clinical, radio-isotopic, angiographic correlation of increased relative perfusion to the area of cerebral infarction. Arch Neurol 30: 65-69
3. Spreafico G, Cammelli F, Gadola G, et al (1987) Luxury perfusion syndrome in cerebral vascular disease evaluated with technetium-99m HM-PAO. Clin Nucl Med 12: 217-218
4. Grunwald F, Zierz S, Broich K, et al (1990) HMPAO-SPECT imaging resembling Alzheimer-type dementia in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS). J Nucl Med 31: 1740-1742
5. Engel AG (1992) Diseases of muscle (myopathies) and neuromuscular junction. In: Wyngaarden JB, Smith LH Jr, Bennet JC (eds) Cecil's textbook of medicine. 19th ed. Saunders, Philadelphia, pp 2250-2268
6. Morita K, Ono S, Fukunaga M, et al (1989) Increased accumulation of N-isopropyl-p-(I-123)-iodoamphetamine in two cases with mitochondrial encephalomyopathy with lactic acidosis and strokelike episodes (MELAS). Neuroradiology 31: 358-361
7. Lewis DH, Longstreth WT, Wilkus R, et al (1993) Hyperemic receptive aphasia on neuroSPECT. CHn Nucl Med 18: 409-412
8. Tamgac F, Moretti JL, Defer G, et al (1994) Non-matched images with I-123 IMP and Tc-99m bicisate single-photon emission tomography in the demonstration of focal hyperemia during the subacute phase of an ischemic stroke. Eur J Nucl Med 21: 254-257
9. Lassen NA, Sperling B (1994) Tc-99m bicisate reliably images CBF in chronic brain diseases but fails to show reflow hyperemia in subacute stroke: report of a multicenter trial of 105 cases comparing Xe-133 and Tc-99m bicisate (ECD, neurolite) measured by SPECT on same day. J Cereb Blood Flow Metab 14 [Suppl 1]: 44-48
10. Bushnell DL, Gupta S, Mlcoch AG, et al (1987) Demonstration of focal hyperemia in acute cerebral infarction with iodine-123 iodoamphetamine. J Nucl Med 28: 1920-1923
11. Kuhl DE, Phelps ME, Kowell AP, et al (1980) Effects of stroke on local cerebral metabolism and perfusion: mapping by emission computed tomography of FDG-18 and NH3-13. Ann Neurol 8: 47-60