Prevalence of TT virus infection in blood donors with elevated ALT in the absence of known hepatitis markers

American Journal of Gastroenterology

Volumn 95, Issue 3, 2000, Pages 772-776

  Cleavinger, Peter J ^a   Persing, David H ^a   Li, Haijing ^a   Moore, S Breanndan ^a   Charlton, Michael R ^a   Sievers, Corey ^a   Therneau, Terry M ^a   Zein, Nizar N ^b  

^a MAYO CLINIC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; VIRUS DNA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; BLOOD DONOR; BLOOD TRANSFUSION; CONTROLLED STUDY; DISEASE MARKER; HEPATITIS; HUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; TORQUE TENO VIRUS;

ALANINE TRANSAMINASE; BASE SEQUENCE; BLOOD DONORS; CIRCOVIRIDAE INFECTIONS; CIRCOVIRUS; CROSS-SECTIONAL STUDIES; DNA, VIRAL; HEPATITIS, VIRAL, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION;

EID: 0033999989     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9270(99)00879-5     Document Type: Article

References (18)

1. Nishizawa T., Okamoto H., Konishi K., et al. A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology. Biochem Biophys Res Commun. 241:1997;92-97.
2. Okamoto H., Nishizawa T., Kato N., et al. Molecular cloning and characterization of a novel DNA virus (TTV) associated with posttransfusion hepatitis of unknown etiology. Hepatol Res. 10:1998;1-16.
3. Charlton M., Adjei P., Poterucha J., et al. TT-virus infection in North American blood donors, patients with fulminant hepatic failure, and cryptogenic cirrhosis. Hepatology. 28:1998;839-842.
4. Okamoto H., Akahane Y., Ukita M., et al. Fecal excretion of a non-enveloped DNA virus (TTV) associated with posttransfusion non-A to G hepatitis. J Med Virol. 56:1998;128-132.
5. Alter H.J. Posttransfusion hepatitis in the United States. Nishioka K., Suzuki H., Mishiro S., et al. Viral hepatitis and liver disease. 1994;551-553 Springer-Verlag, Tokyo.
6. Schreiber G.B., Busch M.P., Kleinman S.H., et al. The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study [see comments]. N Engl J Med. 334:1996;1685-1690.
7. Alter H.J., Bradley D.W. Non-A, non-B hepatitis unrelated to the hepatitis C virus (non-ABC). Semin Liver Dis. 15:1995;110-120.
8. Mason A.L., Perrillo R.P. The A to Z of new hepatotropic agents Human hepatitis viruses and monkey business . Liver Transplant Surg. 2:1996;395-405.
9. Linnen J., Wages J. Jr, Zhang-Keck Z.Y., et al. Molecular cloning and disease association of hepatitis G virus A transfusion-transmissible agent . Science. 271:1996;505-508.
10. Alter M.J., Gallagher M., Morris T.T., et al. Acute non-A-E hepatitis in the United States and the role of hepatitis G virus infection. Sentinel Counties Viral Hepatitis Study Team [see comments]. N Engl J Med. 336:1997;741-746.
11. Alter H.J., Nakatsuji Y., Melpolder J., et al. The incidence of transfusion-associated hepatitis G virus infection and its relation to liver disease [see comments]. N Engl J Med. 336:1997;747-754.
12. Genetic computer group program manual for GCG package. Madison, WI, April, 1991.
13. Kodali V.P., Gordon S.C., Silverman A.L., et al. Cryptogenic liver disease in the United States Further evidence for non-A, non-B, and non-C hepatitis . Am J Gastroenterol. 89:1994;1836-1839.
14. Wright T.L. Etiology of fulminant hepatic failure Is another virus involved? Gastroenterology. 104:1993;640-643.
15. Ferraz M.L., Silva A.E., Macdonald G.A., et al. Fulminant hepatitis in patients undergoing liver transplantation Evidence for a non-A, non-B, non-C, non-D, and non-E syndrome . Liver Transplant Surg. 2:1996;60-66.
16. Takahashi K., Hoshino H., Ohta Y., et al. Very high prevalence of TT virus (TTV) infection in general population of Japan revealed by a new set of PCR primers. Hepatol Res. 12:1998;233-239.
17. Zein N.N., Rakela J., Krawitt E.L., et al. Hepatitis C virus genotypes in the United States Epidemiology, pathogenicity, and response to interferon therapy. Collaborative Study Group . Ann Intern Med. 125:1996;634-639.
18. Miyata H., Tsunoda H. Identification of a novel GC rich 113 nucleatide region to complete the circular, single stranded DNA genome of TT virus, the first human circovirus. J Virol. 73:1999;3582-3586.