Development of analytical and preparative chromatographic separations of novel growth hormone secretagogue compounds

Journal of Chromatography A

Volumn 872, Issue 1-2, 2000, Pages 75-84

  Kennedy, Joseph H ^a   Bowers, John L ^a   Dodge, Jeffrey A ^a   Lugar, Charles W ^a   Shepherd, Timothy A ^a   Sharp, V Scott ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Growth hormone secretagogue; Preparative chromatography

Indexed keywords

GROWTH HORMONE;

ARTICLE; CHIRALITY; CHROMATOGRAPHY; PRIORITY JOURNAL; PURIFICATION; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

GROWTH HORMONE; HETEROCYCLIC COMPOUNDS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033999560     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(99)01286-8     Document Type: Article

References (5)

1. Yang L., Morriello G., Pan Y., Nargund P., Barakat K., Prendegast K., Cheng K., Chan W.W.S., Smith R.G., Patchett A.A. Bioorg. Med. Chem. Lett. 8:1998;759-764.
2. DeVita R.J., Bochis R., Frontier A.J., Kotlair A., Fisher M.H., Schoen W.R., Wyvrantt M.J., Cheng K., Chan W.W.S., Butler B., Jacks T.M., Hickey G.J., Schleim K.D., Leung K., Chen Z., Lee Chiu S.H., Feeney W.P., Cunningham P.K., Smith R.G. J. Med. Chem. 41:1998;1716-1728.
3. Tata J.R., Nargund R.P., Murphy M.M., Johnson D.B.R., Patchett A.A., Cheng K., Wei L., Chan W.W.S., Butler B., Jacks T.M., Hickey G., Smith R. Bioorg. Med. Chem. Lett. 6:1997;663-668.
4. Constanzer M.J., Chavez-Eng C.M., Matuszewski B.K. J. Chromatogr. B. 693:1997;131-137.
5. Kromasil Chiral Phases for HPLC, SFC and SMB, Application Guide, Akzo Nobel.