The stability region of the large virulence plasmid of Shigella flexneri encodes an efficient postsegregational killing system

Journal of Bacteriology

Volumn 182, Issue 9, 2000, Pages 2416-2421

  Sayeed, Sameera ^b   Reaves, Lucretia ^b   Radnedge, Lyndsay ^a,b   Austin, Stuart ^b  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIN; PROTEIN DERIVATIVE;

ARTICLE; BACTERIAL VIRULENCE; CELL GROWTH; CELL KILLING; CELL SURVIVAL; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE REPLICATION; GENETIC STABILITY; NONHUMAN; OPEN READING FRAME; PHENOTYPE; PLASMID; PRIORITY JOURNAL; SHIGELLA FLEXNERI;

DNA, BACTERIAL; MUTAGENESIS; PHENOTYPE; PLASMIDS; SHIGELLA FLEXNERI; VIRULENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; SHIGELLA FLEXNERI;

EID: 0033998991     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.182.9.2416-2421.2000     Document Type: Article

References (20)

1. Abeles, A. 1986. P1 plasmid replication. Purification and DNA-binding activity of the replication protein RepA. J. Biol. Chem. 261:3548-3555.
2. Bachmann, B. J. 1972. Pedigrees of some mutant strains of Escherichia coli K-12. Bacteriol. Rev. 36:525-557.
3. Beaucage, S. L., C. A. Miller, and S. N. Cohen. 1991. Gyrase-dependent stabilization of pSC101 plasmid inheritance by transcriptionally active promoters. EMBO J. 10:2583-2588.
4. Billington, S. J., M. Sinistaj, B. F. Cheetham, A. Ayres, E. K. Moses, M. E. Katz, and J. I. Rood. 1996. Identification of a native Dichelobacter nodosus plasmid and implications for the evolution of the vap regions. Gene 172: 111-116.
5. Bugge-Jensen, R., and K. Gerdes. 1995. Programmed cell death in bacteria: proteic plasmid stabilization systems. Mol. Microbiol. 17:205-210.
6. Churchward, G., D. Belin, and Y. Nagamine. 1984. A pSC101-derived plasmid which shows no sequence homology to other commonly used cloning vectors. Gene 31:165-171.
7. Friedman, S. A., and S. J. Austin. 1988. The P1 plasmid-partition system synthesizes two essential proteins from an autoregulated operon. Plasmid 19:103-112.
8. Hanahan, D. 1983. Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol. 166:557-580.
9. Hashimoto-Gotoh, T., F. C. Franklin, A. Nordheim, and K. N. Timmis. 1981. Specific-purpose plasmid cloning vectors. I. Low copy number, temperature sensitive, mobilization-defective pSC101-derived containment vectors. Gene 16:227-235.
10. Lehnherr, H., E. Maguin, S. Jafri, and M. B. Yarmolinsky. 1993. Plasmid addiction genes of bacteriophage P1: doc, which causes cell death on curing of prophage, and phd, which prevents host death when prophage is retained. J. Mol. Biol. 233:414-428.
11. Makino, S.-I., C. Sasakawa, and M. Yoshikawa. 1988. Genetic relatedness of the basic replicon of the virulence plasmid in shigellae and enteroinvasive Escherichia coli. Microb. Pathog. 5:267-274.
12. Maneewannakul, K., and K. Ippen-Ihler. 1993. Construction and analysis of F plasmid traR, trbJ, and trbH mutants. J. Bacteriol. 175:1528-1531.
13. Martin, K. A., M. A. Davis, and S. Austin. 1991. Fine-structure analysis of the P1 plasmid partition site. J. Bacteriol. 173:3630-3634.
14. Nordstrom, K., and S. J. Austin. 1989. Mechanisms that contribute to the stable segregation of plasmids. Annu. Rev. Genet. 23:37-69.
15. Pullinger, G. D., and A. J. Lax. 1992. A Salmonella dublin virulence plasmid locus that affects bacterial growth under nutrient-limited conditions. Mol. Microbiol. 6:1631-1643.
16. Radnedge, L., M. A. Davis, and S. J. Austin. 1996. P1 and P7 plasmid partition: ParB protein hound to its partition site makes a separate discriminator contact with the DNA that determines species specificity. EMBO J. 15:1155-1162.
17. Radnedge, L., M. A. Davis, B. Youngren, and S. J. Austin. 1997. Plasmid maintenance functions of the large virulence plasmid of Shigella flexneri. J. Bacteriol. 179:3670-3675.
18. Rawlings, D. 1999. Proteic toxin-antitoxin bacterial plasmid addiction systems and their evolution with special reference to the pas system of pTF-FC2. FEMS Microbiol. Lett. 176:269-277.
19. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
20. Yarmolinsky, M. B. 1995. Programmed cell death in bacterial populations. Science 267:836-837.