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Volumn 63, Issue 3, 2000, Pages 125-130

Cyclophosphamide, etoposide, vincristine, adriamycin, and dexamethasone (CEVAD) regimen in refractory multiple myeloma: An International Oncology Study Group (IOSG) Phase II protocol

Author keywords

Adriamycin; Cyclophosphamide; Dexamethasone; Etoposide; Myeloma; Vincristine

Indexed keywords

ALLOPURINOL; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE H2 RECEPTOR ANTAGONIST; VINCRISTINE;

EID: 0033997659     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8652(200003)63:3<125::AID-AJH3>3.0.CO;2-S     Document Type: Article
Times cited : (20)

References (35)
  • 1
    • 0029098733 scopus 로고
    • Current therapy of refractory multiple myeloma
    • Giles FJ. Current therapy of refractory multiple myeloma. Stem Cells (Dayton) 1995:13(Suppl 2):88-105.
    • (1995) Stem Cells (Dayton) , vol.13 , Issue.SUPPL. 2 , pp. 88-105
    • Giles, F.J.1
  • 2
    • 0028793829 scopus 로고
    • Refractory multiple myeloma: Recent advances in therapy
    • Giles FJ. Refractory multiple myeloma: recent advances in therapy. Hematol Pathol 1995;9:121-140.
    • (1995) Hematol Pathol , vol.9 , pp. 121-140
    • Giles, F.J.1
  • 3
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome
    • Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996;335:91-97.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 4
    • 0027991184 scopus 로고
    • Salvage therapy for multiple myeloma: The University of Arkansas experience
    • Barlogie B, Vesole DH, Jagannath S. Salvage therapy for multiple myeloma: the University of Arkansas experience. Mayo Clin Proc 1994;69:787-795.
    • (1994) Mayo Clin Proc , vol.69 , pp. 787-795
    • Barlogie, B.1    Vesole, D.H.2    Jagannath, S.3
  • 5
    • 0021322023 scopus 로고
    • Effective treatment of advanced multiple myeloma refractory to alkylating agents
    • Barlogie B, Smith L, Alexanian R. Effective treatment of advanced multiple myeloma refractory to alkylating agents. N Engl J Med 1984; 310:1353-1356.
    • (1984) N Engl J Med , vol.310 , pp. 1353-1356
    • Barlogie, B.1    Smith, L.2    Alexanian, R.3
  • 6
    • 0028651892 scopus 로고
    • Treatment of refractory multiple myeloma with vincristine, adriamycin, dexamethasone, and with repeated application of cyclophosphamide (C-VAD)
    • Adam Z, Elbl L, Vorlicek J, et al. Treatment of refractory multiple myeloma with vincristine, adriamycin, dexamethasone, and with repeated application of cyclophosphamide (C-VAD). Acta Med Austriaca 1994;21:111-115.
    • (1994) Acta Med Austriaca , vol.21 , pp. 111-115
    • Adam, Z.1    Elbl, L.2    Vorlicek, J.3
  • 7
    • 85173596158 scopus 로고
    • Treatment of melphalan-resistant multiple myeloma with vincristine. BCNU, doxorubicin, and high-dose dexamethasone (VBAD)
    • Blade J, San Miguel J, Sanz-Sanz MA, et al. Treatment of melphalan-resistant multiple myeloma with vincristine. BCNU, doxorubicin, and high-dose dexamethasone (VBAD). Eur J Cancer 1992;1:57-60.
    • (1992) Eur J Cancer , vol.1 , pp. 57-60
    • Blade, J.1    San Miguel, J.2    Sanz-Sanz, M.A.3
  • 8
    • 0026498135 scopus 로고
    • Modified adriamycin-vincristine-dexamethasone (m-VAD) in primary refractory and relapsed plasma cell myeloma: An NCI (Canada) pilot study. The National Cancer Institute of Canada Clinical Trials Group
    • Browman GP, Belch A, Skillings J, et al. Modified adriamycin-vincristine-dexamethasone (m-VAD) in primary refractory and relapsed plasma cell myeloma: an NCI (Canada) pilot study. The National Cancer Institute of Canada Clinical Trials Group. Br J Haematol 1992;82:555-559.
    • (1992) Br J Haematol , vol.82 , pp. 555-559
    • Browman, G.P.1    Belch, A.2    Skillings, J.3
  • 9
    • 0029942953 scopus 로고    scopus 로고
    • A Phase I/II trial of Z-Dex (oral idarubicin and dexamethasone), an oral equivalent of VAD, as initial therapy at diagnosis or progression in multiple myeloma
    • Cook G, Sharp RA, Tansey P, Franklin IM. A Phase I/II trial of Z-Dex (oral idarubicin and dexamethasone), an oral equivalent of VAD, as initial therapy at diagnosis or progression in multiple myeloma. Br J Haematol 1996;93:931-934.
    • (1996) Br J Haematol , vol.93 , pp. 931-934
    • Cook, G.1    Sharp, R.A.2    Tansey, P.3    Franklin, I.M.4
  • 10
    • 0028816350 scopus 로고
    • A Phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma. A Southwest Oncology Group study
    • Dalton WS, Crowley JJ, Salmon SS, et al. A Phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma. A Southwest Oncology Group study. Cancer 1995;75:815-820.
    • (1995) Cancer , vol.75 , pp. 815-820
    • Dalton, W.S.1    Crowley, J.J.2    Salmon, S.S.3
  • 11
    • 0023699971 scopus 로고
    • Infused vincristine and adriamycin with high-dose methylprednisolone (VAMP) in advanced previously treated multiple myeloma patients
    • Forgeson GV, Selby P, Lakhuni S, et al. Infused vincristine and adriamycin with high-dose methylprednisolone (VAMP) in advanced previously treated multiple myeloma patients. Br J Cancer 1988;58:469-473.
    • (1988) Br J Cancer , vol.58 , pp. 469-473
    • Forgeson, G.V.1    Selby, P.2    Lakhuni, S.3
  • 12
    • 0026032469 scopus 로고
    • Refractory myelomatosis treated with mitoxantrone in combination with vincristine and prednisone (NOP-regimen): A Phase II study. The Nordic Myeloma Study Group (NMSG)
    • Gimsing P, Bjerrum OW, Brandt E, et al. Refractory myelomatosis treated with mitoxantrone in combination with vincristine and prednisone (NOP-regimen): a Phase II study. The Nordic Myeloma Study Group (NMSG). Br J Haematol 1991;77:73-79.
    • (1991) Br J Haematol , vol.77 , pp. 73-79
    • Gimsing, P.1    Bjerrum, O.W.2    Brandt, E.3
  • 13
    • 0031440654 scopus 로고    scopus 로고
    • Oral idarubicin, dexamethasone and vincristine (VID) in the treatment of multiple myeloma
    • Glasmacher A, Halerlach T, Gorschluter M, et al. Oral idarubicin, dexamethasone and vincristine (VID) in the treatment of multiple myeloma. Leukemia 1997;11(Suppl 5):S22-26.
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 5
    • Glasmacher, A.1    Halerlach, T.2    Gorschluter, M.3
  • 14
    • 0027199752 scopus 로고
    • VAD regimen in the treatment of resistant multiple myeloma: Slow or fast infusion?
    • Koskela K, Pelliniemi TT, Remes K. VAD regimen in the treatment of resistant multiple myeloma: slow or fast infusion? Leuk Lymphoma 1993;10:347-351.
    • (1993) Leuk Lymphoma , vol.10 , pp. 347-351
    • Koskela, K.1    Pelliniemi, T.T.2    Remes, K.3
  • 16
    • 7844241230 scopus 로고    scopus 로고
    • VAD or VMBCP in multiple myeloma refractory to or relapsing after cyclophosphamide-prednisone therapy (protocol MY 85)
    • Mineur P, Menard JF, Le Loet X, et al. VAD or VMBCP in multiple myeloma refractory to or relapsing after cyclophosphamide-prednisone therapy (protocol MY 85). Br J Haematol 1998;103:512-517.
    • (1998) Br J Haematol , vol.103 , pp. 512-517
    • Mineur, P.1    Menard, J.F.2    Le Loet, X.3
  • 17
    • 0026533910 scopus 로고
    • VAD or VMBCP in severe multiple myeloma. The Groupe d'Etudes et de Recherche sur le Myelome (GERM)
    • Monconduit M, Menard JF, Michaux JL, et al. VAD or VMBCP in severe multiple myeloma. The Groupe d'Etudes et de Recherche sur le Myelome (GERM). Br J Haematol 1992;80:199-204.
    • (1992) Br J Haematol , vol.80 , pp. 199-204
    • Monconduit, M.1    Menard, J.F.2    Michaux, J.L.3
  • 18
    • 0029056875 scopus 로고
    • A randomized study of MOD versus VAD in the treatment of relapsed and resistant multiple myeloma
    • Phillips JK, Sherlaw-Johnson C, Pearce R, et al. A randomized study of MOD versus VAD in the treatment of relapsed and resistant multiple myeloma. Leuk Lymphoma 1995;17:465-472.
    • (1995) Leuk Lymphoma , vol.17 , pp. 465-472
    • Phillips, J.K.1    Sherlaw-Johnson, C.2    Pearce, R.3
  • 19
  • 20
    • 0022888235 scopus 로고
    • The efficacy and toxicity of VAD in the treatment of myeloma and related disorders
    • Sheehan T, Judge M, Parker AC. The efficacy and toxicity of VAD in the treatment of myeloma and related disorders. Scand J Haematol 1986;37:425-428.
    • (1986) Scand J Haematol , vol.37 , pp. 425-428
    • Sheehan, T.1    Judge, M.2    Parker, A.C.3
  • 22
    • 0027182362 scopus 로고
    • EPOCH chemotherapy: Toxicity and efficacy in relapsed and refractory non-Hodgkin's lymphoma
    • Wilson WH, Bryant G, Bates S, et al. EPOCH chemotherapy: toxicity and efficacy in relapsed and refractory non-Hodgkin's lymphoma. J Clin Oncol 1993;11:1573-1582.
    • (1993) J Clin Oncol , vol.11 , pp. 1573-1582
    • Wilson, W.H.1    Bryant, G.2    Bates, S.3
  • 23
    • 0029027893 scopus 로고
    • Controlled trial of dexverapamil, a modulator of multidrug resistance, in lymphomas refractory to EPOCH chemotherapy
    • Wilson WH, Bates SE, Fojo A, et al. Controlled trial of dexverapamil, a modulator of multidrug resistance, in lymphomas refractory to EPOCH chemotherapy. J Clin Oncol 1995;13:1995-2004.
    • (1995) J Clin Oncol , vol.13 , pp. 1995-2004
    • Wilson, W.H.1    Bates, S.E.2    Fojo, A.3
  • 24
    • 0028938612 scopus 로고
    • Infusional chemotherapy (EPOCH) in patients with refractory or relapsed lymphoma
    • Carrion JR, Garcia Arroyo FR, Salinas P. Infusional chemotherapy (EPOCH) in patients with refractory or relapsed lymphoma. Am J Clin Oncol 1995;18:44-46.
    • (1995) Am J Clin Oncol , vol.18 , pp. 44-46
    • Carrion, J.R.1    Garcia Arroyo, F.R.2    Salinas, P.3
  • 25
    • 18844470988 scopus 로고    scopus 로고
    • Prospective randomized placebo-controlled study of granulocyte-macrophage colony-stimulating factor without stem-cell transplantation after high-dose melphalan in patients with multiple myeloma
    • Moreau P, Fiere D, Bezwoda WR, et al. Prospective randomized placebo-controlled study of granulocyte-macrophage colony-stimulating factor without stem-cell transplantation after high-dose melphalan in patients with multiple myeloma. J Clin Oncol 1997;15:660-666.
    • (1997) J Clin Oncol , vol.15 , pp. 660-666
    • Moreau, P.1    Fiere, D.2    Bezwoda, W.R.3
  • 26
    • 0028957805 scopus 로고
    • Human recombinant granulocyte-macrophage colony stimulating factor (hrGM-CSF) improves double hemibody irradiation (DHBI) tolerance in patients with stage III multiple myeloma: A pilot study
    • Troussard X, Macro M, Vie B, et al. Human recombinant granulocyte-macrophage colony stimulating factor (hrGM-CSF) improves double hemibody irradiation (DHBI) tolerance in patients with stage III multiple myeloma: a pilot study. Br J Haematol 1995;89:191-195.
    • (1995) Br J Haematol , vol.89 , pp. 191-195
    • Troussard, X.1    Macro, M.2    Vie, B.3
  • 27
    • 9544257388 scopus 로고    scopus 로고
    • A randomized study of VAD therapy with either concurrent or maintenance interferon in patients with newly diagnosed multiple myeloma
    • Abrahamson GM, Bird JM, Newland AC, et al. A randomized study of VAD therapy with either concurrent or maintenance interferon in patients with newly diagnosed multiple myeloma. Br J Haematol 1996; 94:659-664.
    • (1996) Br J Haematol , vol.94 , pp. 659-664
    • Abrahamson, G.M.1    Bird, J.M.2    Newland, A.C.3
  • 28
    • 0025064260 scopus 로고
    • VAD-based regimens as primary treatment for multiple myeloma
    • Alexanian R, Barlogie B, Tucker S. VAD-based regimens as primary treatment for multiple myeloma. Am J Hematol 1990;33:86-89.
    • (1990) Am J Hematol , vol.33 , pp. 86-89
    • Alexanian, R.1    Barlogie, B.2    Tucker, S.3
  • 29
    • 8544242686 scopus 로고    scopus 로고
    • Maintenance therapy with α-interferon following first-line VAD in multiple myeloma
    • Kars A, Celik I, Kansu E, et al. Maintenance therapy with α-interferon following first-line VAD in multiple myeloma. Eur J Haematol 1997; 59:100-104.
    • (1997) Eur J Haematol , vol.59 , pp. 100-104
    • Kars, A.1    Celik, I.2    Kansu, E.3
  • 30
    • 0024357763 scopus 로고
    • Infusion of vincristine and doxorubicin with oral dexamethasone as first-line therapy for multiple myeloma
    • Samson D, Gaminara E, Newland A, et al. Infusion of vincristine and doxorubicin with oral dexamethasone as first-line therapy for multiple myeloma. Lancet 1989;2:882-885.
    • (1989) Lancet , vol.2 , pp. 882-885
    • Samson, D.1    Gaminara, E.2    Newland, A.3
  • 31
    • 0027423954 scopus 로고
    • Etoposide, doxorubicin, cyclophosphamide and high-dose betamethasone (EACB) as outpatient salvage therapy for refractory multiple myeloma
    • Ohrling M, Bjorkholm M, Osterborg A, et al. Etoposide, doxorubicin, cyclophosphamide and high-dose betamethasone (EACB) as outpatient salvage therapy for refractory multiple myeloma. Eur J Haematol 1993;51:45-49.
    • (1993) Eur J Haematol , vol.51 , pp. 45-49
    • Ohrling, M.1    Bjorkholm, M.2    Osterborg, A.3
  • 32
    • 8044225314 scopus 로고    scopus 로고
    • Dexamethasone, cyclophosphamide, idarubicin and etoposide (DC-IE): A novel, intensive induction chemotherapy regimen for patients with high-risk multiple myeloma
    • Ballester OF, Moscinski LC, Fields KK, et al. Dexamethasone, cyclophosphamide, idarubicin and etoposide (DC-IE): a novel, intensive induction chemotherapy regimen for patients with high-risk multiple myeloma. Br J Haematol 1997;96:746-748.
    • (1997) Br J Haematol , vol.96 , pp. 746-748
    • Ballester, O.F.1    Moscinski, L.C.2    Fields, K.K.3
  • 33
    • 0027410742 scopus 로고
    • Cyclophosphamide and etoposide therapy with GM-CSF for VAD-resistant multiple myeloma
    • Dimopoulos MA, Delasalle KB, Champlin R, Alexanian R. Cyclophosphamide and etoposide therapy with GM-CSF for VAD-resistant multiple myeloma. Br J Haematol 1993;83:240-244.
    • (1993) Br J Haematol , vol.83 , pp. 240-244
    • Dimopoulos, M.A.1    Delasalle, K.B.2    Champlin, R.3    Alexanian, R.4
  • 35
    • 0032434667 scopus 로고    scopus 로고
    • Liposomal daunorubicin: In vitro and in vivo efficacy in multiple myeloma
    • Pratt G, Wiles ME, Rawstron AC, et al. Liposomal daunorubicin: in vitro and in vivo efficacy in multiple myeloma. Hematol Oncol 1998; 16:47-55.
    • (1998) Hematol Oncol , vol.16 , pp. 47-55
    • Pratt, G.1    Wiles, M.E.2    Rawstron, A.C.3


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