Regulated exocytosis in immune function: Are SNARE-proteins involved?

Respiratory Medicine

Volumn 94, Issue 1, 2000, Pages 10-17

  Shukla, A ^a   Berglund, L ^b   Nielsen, L P ^b   Nielsen, S ^b   Hoffmann, H J ^a   Dahl, R ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; CELL SURFACE RECEPTOR; RAB PROTEIN; SNARE PROTEIN; SYNAPTOBREVIN; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN; SYNTAXIN;

B LYMPHOCYTE; BASOPHIL; CELL INFILTRATION; CHRONIC LUNG DISEASE; DENDRITIC CELL; EOSINOPHIL; EXOCYTOSIS; GRANULOCYTE; HUMAN; HUMAN CELL; IMMUNE SYSTEM; INFLAMMATORY CELL; INTRACELLULAR TRANSPORT; MACROPHAGE; MAST CELL; MEDIATOR RELEASE; MEMBRANE FUSION; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN SECRETION; REVIEW; T LYMPHOCYTE;

EID: 0033997225     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1053/rmed.1999.0700     Document Type: Article

References (72)

1. Holgate ST. Asthma: a dynamic disease of inflammation and repair. Ciba Found Symp 1997; 206: 5-28.
2. Seminario MC, Gleich GJ. The role of eosinophils in the pathogenesis of asthma. Curr Opin Immunol 1994; 6: 860-864.
3. Palade G. Intracellular aspects of the process of protein synthesis. Science 1975; 189: 347-358.
4. Burgess TL, Kelly RB. Constitutive and regulated secretion of proteins. Annu Rev Cell Bio! 1987; 3: 243-293.
5. Miller SG, Moore HP. Regulated secretion. Curr Opin Cell Biol 1990; 2: 642-647.
6. Rothman JE. Mechanism of intracellular protein transport. Nature 1994; 372: 55-63.
7. Sollner T, Bennett MK, Whiteheart Sw, Scheller RH, Rothman JE. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 1993; 75: 409-418.
8. Calakos N, Scheller RH. Synaptic vesicle biogenesis, docking, and fusion: a molecular description. Physiol Rev 1996; 76: 1-29.
9. Sudhof TC. The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 1995; 375: 645-653.
10. Blasi J, Binz T, Yamasaki S, Link E, Niemann H, Jahn R. Inhibition of neurotransmitter release by clostridial neurotoxins correlates with specific proteolysis of synaptosomal proteins. J Physiol Paris 1994; 88: 235-241.
11. Schiavo G, Stenbeck G, Rothman JE, Sollner TH. Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proc Natl Acad Sci USA 1997; 94: 997-1001.
12. McMahon HT, Sudhof TC. Synaptic core complex of synaptobrevin, syntaxin, and SNAP25 forms high affinity alpha-SNAP binding site. J Biol Chem 1995; 270:2213-2217.
13. Whiteheart SW, Rossnagel K, Buhrow SA, Brunner M, Jaenicke M, Rothman JE. N-ethymaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion. J Cell Biol 1994; 126: 945-954.
14. Cremona O, De Camilli P. Synaptic vesicle endocytosis. Curr Opin Neurobiol 1997; 7: 323-330.
15. Bennett MK, Garcia-Arraras JE, Elferink LA, et al. The syntaxin family of vesicular transport receptors. Cell 1993; 74: 863-873.
16. Fujita H, Tuma PL, Finnegan CM, Locco L, Hubbard AL. Endogenous syntaxins 2, 3 and 4 exhibit distinct but overlapping patterns of expression at the hepatocyte plasma membrane. Biochem J 1998; 329: 527-538.
17. Bark IC, Wilson MC. Human cDNA clones encoding two different isoforms of the nerve terminal protein SNAP-25. Gene 1994; 139: 291-292.
18. Hess DT, Slater TM, Wilson MC, Skene JH. The 25 kDa synaptosomal-associated protein SNAP-25 is the major methionine-rich polypeptide in rapid axonal transport and a major substrate for palmitoylation in adult CNS. J Neurosci 1992; 12: 4634-4641.
19. Fasshauer D, Otto H, Eliason WK, Jahn R, Brunger AT. Structural changes are associated with soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor formation. J Biol Chem 1997; 272: 28036-28041.
20. Ravichandran V, Chawla A, Roche PA. Identification of a novel syntaxin- and synaptobrevin/VAMP-binding protein, SNAP-23, expressed in non-neuronal tissues. J Biol Chem 1996; 271: 13300-13303.
21. Advani RJ, Bae HR, Bock JB, et al. Seven novel mammalian SNARE proteins localize to distinct membrane compartments. J Biol Chem 1998; 273: 10317-10324.
22. 2+ -induced insulin exocytosis. EMBO J 1996; 15: 6951-6959.
23. Ferro-Novick S, Jahn R. Vesicle fusion from yeast to man. Nature 1994; 370: 191-193.
24. Hay JC, Scheller RH. SNAREs and NSF in targeted membrane fusion. Curr Opin Cell Biol 1997; 9: 505-512.
25. Sudhof TC, Rizo J. Synaptotagmins: C2-domain proteins that regulate membrane traffic. Neuron 1996; 17: 379-388.
26. Butz S, Fernandez-Chacon R, Schmitz F, Jahn R, Sudhof TC. The subcellular localizations of atypical synaptotagmins III and VI. Synaptotagmin iii is enriched in synapses and synaptic plasma membranes but not in synaptic vesicles. J Biol Chem 1999; 274: 18290-18296.
27. 2+-binding domain. J Biol Chem 1998; 273: 15879-15882.
28. Fisher vM, Stahl B, Li C, Sudhof TC, Jahn R. Rab proteins in regulated exocytosis. Trends Biochem Sci 1994; 19: 164-168.
29. Zahraoui, A, Touchot N, Chardin P, Tavitian A. The human Rab genes encode a family of GTP-binding proteins related to yeast YPTI and SEC4 products involved in secretion. J Biol Chem 1998; 264: 12394-12401.
30. Balch WE. Small GTP-binding proteins in vesicular transport. Trends Biochem Sci 1990; 15: 473-477.
31. Klengel R, Paper A, Pittelkow S, Zeuzem S. Differential expression of Rab3 isoforms during differentiation of pancreatic acinar cell line AR42J. Biochem Biophys Res Commun 1997; 236: 719-722.
32. Geppert M, Bolshakov VY, Siegelbaum SA, et al. The role of Rab3A in neurotransmitter release. Nature 1994; 369: 493-497.
33. Geppert M, Goda Y, Stevens CF, Sudhof TC. The small GTP-binding protein Rab3 regulates a late step in synaptic vesicle fusion. Nature 1997; 387: 810-814.
34. Bean AJ, Seifert R, Chen YA, Sacks R, Scheller RH. Hrs-2 is an ATPase implicated in calcium-regulated secretion. Nature 1997; 385: 826-829.
35. Edelmann L, Hanson PI, Chapman ER, Jahn R. Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine. EMBO J 1995; 14: 224-231.
36. Pevsner J, Hsu SC, Scheller RH. N-Secl: a neural-specific syntaxin-binding protein. Proc Natl Acad Sci USA 1994; 91: 1445-1449.
37. Sengelov H, Kjeldsen L, Borregaard N. Control of exocytosis in early neutrophil activation. J Immunol 1993; 150: 1535-1543.
38. Sjolin C, Stendahl O, Dahlgren C. Calcium-induced translocation of annexins to subcellular organelles of human neutrophils. Biochem J 1994; 300: 325-330.
39. Brumell JH, Volchuk A, Sengelov H, et al. Subcellular distribution of docking/fusion proteins in neutrophils, secretory cells with multiple exocytic compartments. J Immunol 1995; 155: 5750-5759.
40. Nobokina S, Egea G, Blasi J, Mollinedo F. Intracellular location of SNAP-25 in human neutrophils. Biochem Biophys Res Commun 1997; 239: 592-597.
41. Mollinedo F, Lazo PA. Identification of two isoforms of the vesicle-membrane fusion protein SNAP-23 in human neutrophils and HL-60 cells. Biochem Biophys Res Commun 1997; 231: 808-812.
42. Abraham SN, Arock M. Mast cells and basophils in innate immunity. Semin Immunol 1998; 10: 373-381.
43. 2+ and guanine nucleotides: an all-or-none event. J Cell Biol 1993; 123: 585-593.
44. Guo Z, Turner C, Castle D. Relocation of the t-SNARE SNAP-23 from lamellipodia-like cell surface projections regulates compound exocytosis in mast cells. Cell 1998; 94: 537-548.
45. 2+ sensor, synaptotagmin I. J Immunol 1998; 161: 5120-5123.
46. Cembrzynaska-Nowak M, Szklarz E, Inglot AD, Teodorczyk-Ingeyan JA. Elevated release of tumor necrosis factor-alpha and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma. Am Rev Respir Dis 1993; 147: 291-295.
47. Hackam DJ, Rotstein OD, Bennett Mk, Klip A, Grinstein S, Manolson MF. Characterization and subcellular localization of target membrane soluble NSF attachment protein receptors (t-SNAREs) in
48. macrophages. Syntaxins 2, 3, and 4 are present on phagosomal membranes. J Immunol 1996; 156: 4377-4383.
49. Pitzurra L, Rossetto O, Chimienti AR, Blasi E, Bistoni F. Tetanus toxin-sensitive VAMP-related proteins are present in murine macrophages. Cell Immunol 1996; 169: 113-116.
50. Alvarez-Dominguez C, Roberts R, Stahl PD. Internalized Listeria monocytogenes modulates intracellular trafficking and delays maturation of the phagosome. J Cell Sei 1997; 110: 731-743.
51. Galli SJ, Dvorak AM, Dovrak HF. Basophils and mast cells: morphologic insights into their biology, secretory patterns, and function. Prog Allergy 1984; 34: 1-141.
52. Nusse O, Lindau M, Cromwell O, Kay AB, Gomperts BD. Intracellular application of guanosine-5′-O-(3-thiotriphosphate) induces exocytotic granule fusion in guinea pig eosinophils. J Exp Med 1990; 171: 775-786.
53. Bjerke T, Hoffmann HJH, Karawajczyk M, Dahl R, Knepper M, Nielsen S. Tetanus toxin light chain cleaves a vesicle associated membrane protein (VAMP) isoform 2 in human blood eosinophils and inhibits the release of granule protein. J Exp Med 1999; submitted.
54. Sacca R, Cuff CA, Ruddle NH. Mediators of inflammation. Cur Opin Immunol 1997; 9: 851-857.
55. Darsow T, Reider SE, Emr SD. A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J Ceil Biol 1997; 138: 517-529.
56. Broadie K, Prokop A, Bellen HJ, O'Kane CJ, Schulze KL, Sweeney ST. Syntaxin and synaptobrevin function downstream of vesicle docking in Drosophila. Neuron 1995; 15: 663-673.
57. Kretzschmar S, Volknandt W, Zimmermann H. Colocalization on the same synaptic vesicles of syntaxin and SNAP-25 with synaptic vesicles proteins: a reevaluation of functional models required? Neurosci Res 1996; 26: 141-148.
58. 2+ sensitivity. J Cell Biol 1998; 143: 1845-1857.
59. Hong RM, Mori H, Fukui T, et al. Association of N-ethylmaleimide-sensitive factor with synaptic vesicles. FEBS Lett 1994; 350: 253-257.
60. Otto H, Hanson PI, Jahn R. Assembly and disassembly of a ternary complex of synaptobrevin, syntaxin, and SNAP-25 in the membrane of synaptic vesicles. Proc Natl Acad Sei USA 1997; 94: 6197-6201.
61. Hanson PI, Otto H, Barton N, Jahn R. The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin. J Biol Chem 1995; 270: 16955-16961.
62. Bennett MK, Calakos N, Scheller RH. Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. Science 1992; 257: 255-259.
63. Oyler GA, Higgins GA, Hart RA, et al. The identification of a novel synaptosomal-associated
64. protein, SNAP-25, differentially expressed by neuronal subpopulations. J Cell Biol 1989; 109: 3039-3052.
65. Wong PP, Daneman N, Volchuk A, et al. Tissue distribution of SNAP-23 and its subcellular localization in 3T3-L1 cells. Biochem Biophys Res Commun 1997; 230: 64-68.
66. Baumert M, Maycox PR, Navone F, De CP, Jahn R. Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain. EMBO J 1989; 8: 379-384.
67. Chilcote TJ, Galli T, Mundigl O, et al. Cellubrevin and synaptobrevins: similar subcellular localization and biochemical properties in PC12 cells. J Cell Biol 1995; 129: 219-231.
68. Trimble WS, Cowan DM, Scheller RH. VAMP-1: a synaptic vesicle-associated integral membrane protein. Proc Nad Acad Sci USA 1998; 85: 4538-4542.
69. Whiteheart SW, Griff IC, Brunner M, et al. SNAP family of NSF attachment proteins includes a brain-specific isoform. Nature 1993; 362: 353-355.
70. Brose N, Petrenko AG, Sudhof TC, Jahn R. Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science 1992; 256: 1021-1025.
71. Washbourne P, Schiavo G, Montecucco C. Vesicle-associated membrane protein-2 (synaptobrevin-2) forms a complex with synaptophysin. Biochem J 1995; 305: 721-724.
72. Wiedenmann B, Franke WW. Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell 1985; 41: 1017-1028.