Receptor-binding conformation of the 'ELR' motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 Å resolution

Proteins: Structure, Function and Genetics

Volumn 38, Issue 4, 2000, Pages 361-367

  Gerber, Nancy ^a   Lowman, Henry ^a   Artis, Dean R ^a   Eigenbrot, Charles ^a  

^a GENENTECH INC   (United States)

Author keywords

Design; Inhibitor; Intermolecular; Minimization; Proline; Rational

Indexed keywords

INTERLEUKIN 8;

AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR BINDING;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENS, CD; CRYSTALLOGRAPHY, X-RAY; HUMANS; INTERLEUKIN-8; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, CYTOKINE; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-8A;

EID: 0033997142     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(20000301)38:4<361::AID-PROT2>3.0.CO;2-0     Document Type: Article

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