Mechanism of thrombospondin-1 anti-HIV-1 activity

AIDS Patient Care and STDs

Volumn 14, Issue 4, 2000, Pages 211-214

  Crombie, René ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THROMBOSPONDIN 1;

ANTIVIRAL ACTIVITY; CONFERENCE PAPER; DRUG ACTIVITY; DRUG EFFECT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; VIRUS INFECTIVITY;

HIV INFECTIONS; HIV-1; HUMANS; MICROBIAL SENSITIVITY TESTS; SENSITIVITY AND SPECIFICITY; THROMBOSPONDIN 1;

EID: 0033996737     PISSN: 10872914     EISSN: None     Source Type: Journal    
DOI: 10.1089/108729100317821     Document Type: Conference Paper

References (9)

1. Lahav J. Thrombospondin. Boca Raton, FL: CRC Press, 1993.
2. Bornstein P. Thrombospondins: Structure and regulation of expression. FASEB 1992;6:3222-3229.
3. Pearce SFA, Wu J, Silverstein RL. Recombinant GST/CD36 fusion proteins define a thrombospondin binding domain: Evidence for a single calcium-dependent binding site on CD36. J Biol Chem 1995;270: 2981-2986.
4. Crombie R, Silverstein RL. Lysosomal integral membrane protein LIMPII binds tnrombospondin-1: Structure-function homology with the cell adhesion molecule CD36 defines a conserved recognition motif. J Biol Chem 1998;273:4855-4866.
5. Crombie R, Silverstein RL, MacLow C, Pearce SFA, Nachman RL, Laurence J. Identification of a CD36-related thrombospondin-1 binding domain in HIV-1 envelope glycoprotein gp120: Relationship to HIV-1-specific inhibitory factors in human saliva. J Exp Med 1998;187:25-35.
6. Arnory J, Martin N, Levy J, Wara D. The large molecular weight glycoprotein MG1, a component of human saliva, inhibits HIV-1 infectivity. Clin Res 1992;40:51A.
7. McNeely TB, Dealy M, Dripps DJ, Orenstein JM, Eisenberg SP, Wahl SM. Secretory leukocyte protease inhibitor: A human saliva protein exhibiting anti-human immunodeficiency virus-1 activity in vitro. J Clin Invest 1995;96:456-464.
8. Su HL, Boackle RJ. Interaction of the envelope glycoprotein of human immunodeficiency virus with C1q and fibronectin under conditions present in saliva. Mol Immunol 1991;28:811-817.
9. Lahav J. The functions of thrombospondin and its involvement in physiology and pathophysiology. Biochim Biophys Acta 1993;1182:1-14.