Local injection of anti-cancer drugs bound to carbon particles for early gastric cancer - A pilot study

Hepato-Gastroenterology

Volumn 47, Issue 32, 2000, Pages 575-578

  Hagiwara, Akeo ^a   Torii, Tsuyoshi ^b   Sawai, Kiyoshi ^a   Sakakura, Chouhei ^a   Shirasu, Morio ^a   Ohgaki, Masaharu ^a   Imanishi, Tsutomu ^a   Yamasaki, Junya ^a   Takahashi, Toshio ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Torii Clinic   (Japan)

Author keywords

Activated carbon particles; Anti cancer drug; Clinical trials; Gastric cancer; Lymph node metastasis

Indexed keywords

AC 1500; ACTIVATED CARBON; METHOTREXATE; MITOMYCIN C; POVIDONE; PVP K 30R;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; EPIGASTRIC PAIN; FEMALE; FEVER; GASTROSCOPE; HISTOLOGY; HUMAN; LEUKOPENIA; LYMPH NODE METASTASIS; MALE; PRIORITY JOURNAL; STOMACH CANCER; ULCER;

AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHARCOAL; COMBINED MODALITY THERAPY; FEMALE; GASTRECTOMY; HUMANS; INJECTIONS, INTRALESIONAL; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MALE; METHOTREXATE; MIDDLE AGED; MITOMYCIN; NEOADJUVANT THERAPY; PILOT PROJECTS; STOMACH; STOMACH NEOPLASMS;

EID: 0033996502     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. 1 Moreaux J, Bougaran J: Early gastric cancer, a 25-year surgical experience. Ann Surg 1993; 217:347-355.
2. 2 Sano T, Kobori O, Muto T: Lymph node metastasis from early gastric cancer: endoscopic resection of tmour. Br J Surg 1992; 79:241-244.
3. 3 Takekoshi T, Takagi K, Kato: Radical endoscopic treatment of early gastric cancer. Jpn J Cancer Res 1990; 37:111-126.
4. 4 Sakita T, Koyama S, Ishii M, et al: Early cancer of the stomach treated successfully with an endoscopic neodymium-YAG laser. Am J 1981; 76:441-445.9
5. 5 Ballard BE: Biopharmaceutical considerations in subcutaneous and intramuscular drug administration. J Pharm Sciences 1968; 57:357-378.
6. 6 Hagiwara A, Takahashi T, Ueda T, et al: Activated carbon particles as anti-cancer drug carrier into regional lymph nodes. Anti-Cancer Drug Design 1987; 1:313-321.
7. 7 Hagiwara A, Takahashi T, Sawai K, et al: Methotrexate bound to carbon particles used for treating cancers with lymph node metastases in animal experiments and clinical pilot study. Cancer 1996; 78:199-209.
8. 8 Hagiwara A, Takahashi T, Ueda T, et al: The enhanced chemotherapeutic effect on lymphnodal metastasis by using charcoal particles adsorbing mitomycin C. Nisseki Igaku (Journal of Japanese Red Cross Hospitals) 1985; 37:119-124. (In Japanese)
9. 9 Hagiwara A, Takahashi T, Sawai K, et al: Lymph nodal vital staining with newer carbon particle suspensions compared with india ink. Lymphology 1992; 25:84-89.
10. 10 Rusznyak I, Foldi M, Szabo G: Absorption into lymph capillaries. In: Youlten L (Ed.). Lymphatics & lymph circulation, physiology & pathology. 2nd Edition. London: Pergamon Press, 1967; pp. 418-474.