Gut epithelial apoptosis after severe burn: Effects of gut hypoperfusion

Journal of the American College of Surgeons

Volumn 190, Issue 3, 2000, Pages 281-287

  Ramzy, Peter I ^a   Wolf, Steven E ^a   Irtun, Oivind ^a   Hart, David W ^a   Thompson, James C ^a   Herndon, David N ^a  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD FLOW; BURN; CELL DEATH; CONTROLLED STUDY; INTESTINE EPITHELIUM CELL; INTESTINE PERFUSION; LASER FLOWMETER; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; REGRESSION ANALYSIS; SUPERIOR MESENTERIC ARTERY;

ANIMALS; BURNS; CELL DEATH; EPITHELIUM; INTESTINES; LINEAR MODELS; MESENTERY; RATS; RATS, INBRED F344; REGIONAL BLOOD FLOW;

EID: 0033995428     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1072-7515(99)00269-0     Document Type: Article

References (16)

1. Jones WG, Minei JP, Barber AE, et al. Splanchnic vasoconstriction and bacterial translocation after thermal injury. Am J Physiol 1991;261:H1190-H1196.
2. Carter EA, Gonnella A, Tompkins RG. Increased transcellular permeability of rat small intestine after thermal injury. Burns 1992;18:117-120.
3. LeVoyer T, Cioffi WG Jr, Pratt L, et al. Alterations in intestinal permeability after thermal injury. Arch Surg 1992;127: 26-30.
4. Deitch EA, Ma L, Ma JW, Berg RD. Lethal burn induced bacterial translocation: role of genetic resistance. J Trauma 1989;29: 1480-1487.
5. Ryan CM, Yarmush ML, Burke JF, Tompkins RG. Increased gut permeability early after burns correlates with the extent of burn injury. Crit Care Med 1992;20:1508-1512.
6. Wolf SE, Ikeda H, Matin S, et al. Cutaneous burn increases apoptosis in the gut epithelium of mice. J Am Coll Surg 1999; 188:10-16.
7. Lightfoot E, Horton JW, Maass DL, et al. Major burn trauma in rats promotes cardiac and gastrointestinal apoptosis. Shock 1999;11;129-134.
8. Herndon DN, Wilmore DW, Mason AD. Development and analysis of a small animal model simulating the human postburn hypermetabolic response. J Surg Res 1978;25:394-403.
9. Jones BA, Gores GJ. Physiology and pathophysiology of apoptosis in epithelial cells of the liver, pancreas, and intestine. Am J Physiol 1997;273:G1174-G1188.
10. Xu YX, Ayala A, Monfils B, et al. Mechanism of intestinal mucosal immune dysfunction following trauma-hemorrhage: increased apoptosis associated with elevated Fas expression in Peyer's patches. J Surg Res 1997;70:55-60.
11. Saydjari R, Beerthuizen GI, Townsend CM Jr, et al. Bacterial translocation and its relationship to visceral blood flow, gut mucosal ornithine decarboxylase activity, and DNA in pigs. J Trauma 1991;31:639-644.
12. Herndon DN, Morris SE, Coffey JA, et al. The effect of mucosal integrity and mesenteric blood flow on enteric translocation of microorganisms in cutaneous thermal injury. Second Vienna Shock Forum 1989;377-382.
13. Myers SI, Minei JP, Casteneda A, Hernandez R. Differential effects of acute thermal injury on rat splanchnic and renal blood flow and prostanoid release. Prostaglandins Leukot Essent Fatty Acids 1995;53:439-444.
14. Atiles L, Mileski W, Spann K, et al. Early assessment of pediatric burn wounds by laser doppler flowmetry. J Burn Care Rehabil 1995;16:596-601.
15. Saydjari R, Tokyay R, Zeigler ST, et al. Post burn gastrointestinal vasoconstriction increases bacterial and endoroxin translocation. J Appl Physiol 1993;74:1521-1527.
16. Noda T, Iwakiri R, Fujimoto K, et al. Programmed cell death induced by ischemia-reperfusion in rat intestinal mucosa. Am J Physiol 1998;274:G270-G276.