A randomized, controlled trial comparing insulin lispro with human soluble insulin in patients with Type 1 diabetes on intensified insulin therapy

Diabetic Medicine

Volumn 17, Issue 3, 2000, Pages 209-214

  Gale, Edwin A M ^a  

^a SOUTHMEAD HOSPITAL   (United Kingdom)

Author keywords

Hypoglycaemia; Insulin analogues; Insulin therapy; Randomized controlled trial; Type 1 diabetes mellitus

Indexed keywords

HUMAN INSULIN; INSULIN LISPRO; ISOPHANE INSULIN; NEUTRAL INSULIN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; MAJOR CLINICAL STUDY; MALE; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADOLESCENT; ADULT; BLOOD GLUCOSE; CROSS-OVER STUDIES; DIABETES MELLITUS, TYPE 1; DIET; DOUBLE-BLIND METHOD; FEMALE; FOOD; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MIDDLE AGED; PATIENT SATISFACTION; PROSPECTIVE STUDIES; QUALITY OF LIFE;

EID: 0033995176     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.2000.00258.x     Document Type: Article

References (17)

1. 1 Kang S, Brange J, Burch A, Volund A, Owens D. Subcutaneous insulin absorption explained by insulin's physicochemical properties. Evidence from absorption studies of soluble human insulin and insulin analogues in humans. Diabetes Care 1991; 14: 942-948.
2. 2 Howey DC, Bowsher BR, Brunelle RL, Woodworth JR. [Lys (B28), Pro (B29)]-human insulin. A rapidly absorbed analog of human insulin Diabetes 1994; 43: 396-402.
3. 3 Zinman B, Tildesley H, Chiasson J-L, Tsui E, Strack T. Insulin lispro in CSII. Results of a double blind trial. Diabetes 1997; 46: 440-443.
4. 4 Zinman B, Ross S, Campos RV, Strack S, the Canadian Lispro Study Group. Effectiveness of human ultralente versus NPH insulin in providing basal insulin replacement for an insulin lispro multiple injection regimen. A double blind randomized prospective trial. Diabetes Care 1999; 22: 603-608.
5. 5 Lean MEJ, Ng LL, Tennison BR. Interval between insulin injection and eating in relation to blood glucose control in adult diabetics. Br Med Journal 1985; 290: 105-108.
6. 6 Heinemann L. Do insulin treated diabetic patients use an injection-meal interval in daily life? Diabetic Med 1995; 12: 449-450.
7. 7 Bradley C. Handbook of Psychology and Diabetes: A Guide to Psychological Measurement in Diabetes Research and Practice. Chur, Switzerland: Harwood Academic Publishers, 1994.
8. 8 Koch GG. The use of non-parametric methods in the statistical analysis of the two period changeover design. Biometrics 1972; 28: 577-584.
9. 9 Taulbee JD. A note on the use of non-parametric methods in the statistical analysis of the two-period changeover design. Biometrics 1982; 38: 1053-1055.
10. 10 Nagelkerke NJD, Hart AAM, Costing J. The two period binary-response cross-over trial. Biom J 1986; 28: 863-869.
11. 11 Holleman F, Hoekstra JBL. Insulin lispro. New England J Med 1997; 337: 176-183.
12. 12 Anderson JH, Brunelle RL, Koivisto VA, Pfutzner A, Trautmann ME, Vignati L et al. Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment. Diabetes 1997; 46: 265-270.
13. 13 Ahmed ABE, Home PD. The effect of the insulin analog lispro on nighttime blood glucose control in type 1 diabetic patients. Diabetes Care 1998; 21: 32-37.
14. 14 Brunelle RL, Llewelyn J, Anderson JH Jr, Gale EAM, Koivisto VA. Meta-analysis of the effect of insulin lispro on severe hypoglycemia in patients with type 1 diabetes. Diabetes Care 1998; 21: 1726-1731.
15. 15 The Diabetes Control and Complications Trial Research Group. Hypoglycemia in the diabetes control and complications trial. Diabetes 1997; 46: 271-286.
16. 16 Home PD, Lindholm A, Hylleberg B, Round P for the UK Insulin Aspart Study Group. Improved glycaemic control with insulin aspart. Diabetes Care 1998; 21: 1904-1909.
17. 17 Ebeling P, Lalli C, Jansson P-A, Bolli GB, Smith U, Koivisto VA. Strategies toward improved control during insulin lispro therapy in IDDM. Diabetes Care 1997; 20: 1287-1289.