Formation of HDL-like complexes from apolipoprotein A-I(M) and DMPC

International Journal of Pharmaceutics

Volumn 194, Issue 1, 2000, Pages 21-38

  Suurkuusk, Malin ^a   Singh, Satish K ^a  

^a PFIZER INC   (United States)

Author keywords

Apolipoprotein A I(M); Circular dichroism; Differential scanning calorimetry; Phospholipid protein complex; Reconstituted lipoprotein; Titration calorimetry

Indexed keywords

APOLIPOPROTEIN A1; DIMYRISTOYLPHOSPHATIDYLCHOLINE; HIGH DENSITY LIPOPROTEIN;

ARTICLE; CIRCULAR DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG SYNTHESIS; PRIORITY JOURNAL; THERMODYNAMICS;

APOLIPOPROTEIN A-I; CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; DIMYRISTOYLPHOSPHATIDYLCHOLINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LEAST-SQUARES ANALYSIS; LIPOPROTEINS, HDL; PARTICLE SIZE; RECOMBINANT PROTEINS; TEMPERATURE; TITRIMETRY;

EID: 0033992178     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00312-9     Document Type: Article

References (36)

1. Andersson L.-O. Pharmacology of apolipoprotein A-I. Curr. Opin. Lipidol. 8:1997;225-228.
2. Badimon J., Badimon L., Fuster V. Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit. J. Clin. Invest. 85:1990;1234-1241.
3. Brewer Jr H.B., Fairwell T., LaRue A., Ronan R., Houser A., Bronzert T.J. The amino acid sequence of human apoA-I, an apolipoprotein isolated from high density lipoproteins. Biochem. Biophys. Res. Com. 80:1978;623-630.
4. Calabresi L., Vecchio G., Frigerio F., Vavassori L., Sirtori C.R., Franceschini G. Reconstituted high-density lipoproteins with a disulfide-linked apolipoprotein A-1 dimer: evidence for restricted particle size heterogeneity. Biochemistry. 36:1997;12428-12433.
5. Milano dimer. J. Biol. Chem. 269:1994;32168-32174.
6. Davidson W.S., Hazlett T., Mantulin W.W., Jonas A. The role of apolipoprotein AI domains in lipid binding. Proc. Natl. Acad. Sci. USA. 93:1996;13605-13610.
7. Derksen A., Gantz D., Small D.M. Calorimetry of apolipoprotein-A1 binding to phosphatidylcholine-triolein-cholesterol emulsions. Biophys. J. 70:1996;330-338.
8. Edwards W.L., Bush S.F., Mattingly T.W., Weisgraber K.H. Raman spectroscopic study of boundary lipid in 1,2-dipalmitoylphosphatidylcholine/apolipoprotein A-I recombinants. Spectrochim. Acta. 49:1993;2027-2038.
9. Fielding C.J., Fielding P.E. Molecular physiology of reverse cholesterol transport. J. Lip. Res. 36:1995;211-228.
10. Franceschini G., Apebe P., Calabresi L., Gualandri V., Sirtori C.R. Apolipoprotein A-I, Milano variant: genetic, clinical, and biochemical features. Atherosclerosis Rev. 16:1987;149-159.
11. Frank P.G., Bergeron J., Emmanuel F., Lavigne J.-P., Sparks D.L., Denèfle P., Rassart E., Marcel Y.L. Deletion of central α-helices in human apolipoprotein A-I: effect on phospholipid association. Biochemistry. 36:1997;1798-1806.
12. Glomset J.A. The plasma lecithin:cholesterol acyltransferase reaction. J. Lipid Res. 9:1968;155-162.
13. Gordon D.J., Rifkind B.M. High-density lipoprotein - the clinical implications of recent studies. N. Engl. J. Med. 321:1989;1311-1316.
14. Gursky O., Atkinson D. Thermal unfolding of human high-density apolipoprotein A-I: implications for a lipid-free molten globular state. Proc. Natl. Acad. Sci. USA. 93:1996;2991-2995.
15. Jonas A., Drengler S.M., Kaplan J.S. Interaction of apolipoprotein A-I with dimyristoylphosphatidylcholine particles of various sizes. J. Biol. Chem. 256:1981;2420-2426.
16. Jonas A., Drengler S.M., Patterson B.W. Two types of complexes formed by the interaction of apolipoprotein Aa-I with vesicles of l-α-dimyristoylphosphatidylcholine. J. Biol. Chem. 255:1980;2183-2189.
17. Kodama M., Miyata T., Takaichi Y. Calorimetric investigations of phase transitions of sonicated vesicles of dimyristoylphosphatidylcholine. Biochim. Biophys. Acta. 1169:1993;90-97.
18. Laccotripe M., Makrides S.C., Jonas A., Zannis V.I. The carboxyl-terminal hydrophobic residues of apolipoprotein A-I affects its rate of binding and its association with high density lipoprotein. J. Biol. Chem. 272:1997;17511-17522.
19. Lecompte M.-F., Bras A.-C., Dousset N., Portas I., Salvayre R., Ayrault-Jarrier M. Binding steps of apolipoprotein A-I with phospholipid monolayers: adsorption and penetration. Biochemistry. 37:1998;16165-16171.
20. Meng Q.-H., Calabresi L., Fruchart J.-C., Marcel Y.L. Apolipoprotein A-I domains involved in the activation of lecithin:cholesterol acyltransferase. J. Biol. Chem. 268:1993;16966-16973.
21. Palguanachari M.N., Mishra V.K., Lund-Katz S., Phillips M.C., Adeyeye S.O., Alluri S., Anantharamaiah G.M., Segrest J.P. Only the two end helixes of eigth tandem amphiphatic helical domains of human apo A-I have significant lipid affinity. Arterioscler. Thromb. Vasc. Biol. 16:1996;328-338.
22. Phillips J.C., Wriggers W., Li Z., Jonas A., Schulten K. Predicting the structure of apolipoprotein A-I in reconstituted high-density lipoprotein disks. Biophys. J. 73:1997;2337-2346.
23. Pownall H.J., Hsu F.J., Rosseneu M., Peeters H., Gotto A.M., Jackson R.L. Thermodynamics of lipid protein associations thermodynamics of helix formation in the association of high density apolipoprotein A-I (ApoA-I) to myristoyl phosphatidylcholine. Biochim. Biophys. Acta. 488:1977;190-197.
24. Rogers D.P., Brouillette C.G., Engler J.A., Tendian S.W., Roberts L., Mishra V.K., Anantharmaiah G.M., Lund-Katz S., Phillips M.C., Ray M.J. Truncation of the amino terminus of human apolipoprotein A-I substantially alters only the lipid-free conformation. Biochemistry. 36:1997;288-300.
25. Rogers D.P., Roberts L.M., Lebowitz J., Engler J.A., Brouillette C.G. Structural analysis of apolipoprotein A-I: effects of amino- and carboxy-terminal deletions on the lipid-free structure. Biochemistry. 37:1998;945-955.
26. Rosseneu M., Soetewey F., Middelhoff G., Peeters H., Brown W.V. Studies of the lipid binding characteristics of the apolipoproteins from human high density lipoprotein II. Calorimetry of the binding of Apo AI and Apo AII with phospholipids. Biochim. Biophys. Acta. 441:1976;68-80.
27. Rosseneu M.Y., Soetewey F., Blaton V., Lievens J., Peeters H. Microcalorimetric study of phospholipid binding to human Apo-HDL. Chem. Phys. Lipid. 13:1974;203-214.
28. Scholtz J.M., Marqusee S., Baldwin R.L., York E.J., Stewart J.M., Santoro M., Bolen D.W. Calorimetric determination of the enthapy change for the α-helix to coil transition of an alanine peptide in water. Proc. Natl. Acad. Sci. USA. 88:1991;2854-2858.
29. Seelig J. Titration calorimetry of lipid-peptide interactions. Biochim. Biophys. Acta. 1331:1997;103-116.
30. Segrest J.P., Jones M.K., DeLoof H., Brouillette C.G., Venkatachalapathi Y.V., Anantharamaiah G.M. The amphiphathic helix in the exchangeable apolipoproteins: a review of secondary structure and function. J. Lipid Res. 33:1992;141-166.
31. Suurkuusk M., Singh S.K. Microcalorimetric study of the interaction of 1-hexanol with dimyristoylphosphatidylcholine vesicles. Chem. Phys. Lipid. 94:1998;119-138.
32. Swaney J.B. Mechanisms of protein-lipid interaction. J. Biol. Chem. 255:1980;8791-8797.
33. Swaney J.B., Chang B.C. Thermal dependence of apolipoprotein A-I-phospholipid recombination. Biochemistry. 19:1980;5637-5644.
34. Tall A.R., Small D.M., Deckelbaum R.J., Shipley G.G. Structure and thermodynamic properties of high density lipoprotein recombinants. J. Biol. Chem. 252:1977;4701-4711.
35. Wald J.H., Krul E.S., Jonas A. Investigation of the lipid domains and apolipoprotein orientation in reconstituted high density lipoproteins by fluorescence and IR methods. J. Biol. Chem. 265:1990;20044-20050.
36. Milano. J. Biol. Chem. 258:1983;2508-2513.