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Volumn 59, Issue 2, 2000, Pages 161-165

Inter-species variation in the metabolism and inhibition of N-[(2'-dimethylamino)ethyl]acridine-4-carboxamide (DACA) by aldehyde oxidase

Author keywords

Acridine carboxamide; Aldehyde oxidase; Species

Indexed keywords

ACRIDINE DERIVATIVE; ALDEHYDE OXIDASE; AMSACRINE; ANTINEOPLASTIC AGENT; LIVER ENZYME; MENADIONE;

EID: 0033990931     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00323-8     Document Type: Article
Times cited : (36)

References (18)
  • 1
    • 0024589187 scopus 로고
    • Selectivity of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide towards Lewis lung carcinoma and human tumour cell lines in vitro
    • Finlay G.J., Baguley B. Selectivity of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide towards Lewis lung carcinoma and human tumour cell lines in vitro. Eur J Cancer Clin Oncol. 25:1989;271-277.
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 271-277
    • Finlay, G.J.1    Baguley, B.2
  • 2
    • 0027284902 scopus 로고
    • Metabolism of the experimental antitumor agent acridine carboxamide in the mouse
    • Robertson I.G.C., Palmer B.D., Paxton J.W., Bland T.J. Metabolism of the experimental antitumor agent acridine carboxamide in the mouse. Drug Metab Dispos. 21:1993;530-536.
    • (1993) Drug Metab Dispos , vol.21 , pp. 530-536
    • Robertson, I.G.C.1    Palmer, B.D.2    Paxton, J.W.3    Bland, T.J.4
  • 3
    • 0025933915 scopus 로고
    • Cytosol mediated metabolism of the experimental antitumour agent acridine carboxamide to the 9-acridone derivative
    • Robertson I.G.C., Palmer B.D., Officer M., Siegers D.J., Paxton J.W., Shaw G.J. Cytosol mediated metabolism of the experimental antitumour agent acridine carboxamide to the 9-acridone derivative. Biochem Pharmacol. 42:1991;1879-1884.
    • (1991) Biochem Pharmacol , vol.42 , pp. 1879-1884
    • Robertson, I.G.C.1    Palmer, B.D.2    Officer, M.3    Siegers, D.J.4    Paxton, J.W.5    Shaw, G.J.6
  • 4
    • 0027195014 scopus 로고
    • Rat hepatocyte-mediated metabolism of the experimental anti-tumour agent N-[2′-(dimethylamino)ethyl]acridine-4-carboxamide
    • Schlemper B., Siegers D.J., Paxton J.W., Robertson I.G.C. Rat hepatocyte-mediated metabolism of the experimental anti-tumour agent N-[2′-(dimethylamino)ethyl]acridine-4-carboxamide. Xenobiotica. 23:1993;361-371.
    • (1993) Xenobiotica , vol.23 , pp. 361-371
    • Schlemper, B.1    Siegers, D.J.2    Paxton, J.W.3    Robertson, I.G.C.4
  • 8
    • 0026495982 scopus 로고
    • Role of guinea pig and rabbit hepatic aldehyde oxidase in oxidative in vitro metabolism of cinchona antimalarials
    • Beedham C., Al-Tayib Y., Smith J.A. Role of guinea pig and rabbit hepatic aldehyde oxidase in oxidative in vitro metabolism of cinchona antimalarials. Drug Metab Dispos. 20:1992;1-6.
    • (1992) Drug Metab Dispos , vol.20 , pp. 1-6
    • Beedham, C.1    Al-Tayib, Y.2    Smith, J.A.3
  • 9
    • 0028945438 scopus 로고
    • Structural and catalytic properties of the mammalian flavin-containing monooxygenase
    • Cashman J.R. Structural and catalytic properties of the mammalian flavin-containing monooxygenase. Chem Res Toxicol. 8:1995;165-182.
    • (1995) Chem Res Toxicol , vol.8 , pp. 165-182
    • Cashman, J.R.1
  • 10
    • 0027198768 scopus 로고
    • Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide
    • Robertson I.G.C., Bland T.J. Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide. Biochem Pharmacol. 45:1993;2159-2162.
    • (1993) Biochem Pharmacol , vol.45 , pp. 2159-2162
    • Robertson, I.G.C.1    Bland, T.J.2
  • 11
    • 0028256155 scopus 로고
    • Methadone: A potent inhibitor of rat aldehyde oxidase
    • Robertson I.G.C., Gamage R.S.K.A. Methadone A potent inhibitor of rat aldehyde oxidase . Biochem Pharmacol. 47:1993;584-587.
    • (1993) Biochem Pharmacol , vol.47 , pp. 584-587
    • Robertson, I.G.C.1    Gamage, R.S.K.A.2
  • 13
    • 0002805556 scopus 로고
    • MKMODEL: A modelling tool for microcomputers. Pharmacokinetic evaluation and comparison with standard computer programs
    • Holford N.H.G. MKMODEL A modelling tool for microcomputers. Pharmacokinetic evaluation and comparison with standard computer programs . Clin Exp Pharmacol Physiol. 12:(Suppl 9):1985;95.
    • (1985) Clin Exp Pharmacol Physiol , vol.12 , Issue.SUPPL. 9 , pp. 95
    • Holford, N.H.G.1
  • 14
    • 0028059953 scopus 로고
    • Comparison of levels of aldehyde oxidase with cytochrome P450 activities in human liver in vitro
    • Rodrigues A.D. Comparison of levels of aldehyde oxidase with cytochrome P450 activities in human liver in vitro. Biochem Pharmacol. 48:1994;197-200.
    • (1994) Biochem Pharmacol , vol.48 , pp. 197-200
    • Rodrigues, A.D.1
  • 15
    • 0029553627 scopus 로고
    • Strain differences in liver aldehyde oxidase activity in rats
    • Sugihara K., Kitamura S., Tatsumi K. Strain differences in liver aldehyde oxidase activity in rats. Biochem Mol Biol Int. 37:1995;861-869.
    • (1995) Biochem Mol Biol Int , vol.37 , pp. 861-869
    • Sugihara, K.1    Kitamura, S.2    Tatsumi, K.3
  • 16
    • 0031009348 scopus 로고    scopus 로고
    • Differences in aldehyde oxidase activity in cytosolic preparations of human and monkey liver
    • Sugihara K., Kitamura S., Tatsumi K., Asahara T., Dohi K. Differences in aldehyde oxidase activity in cytosolic preparations of human and monkey liver. Biochem Mol Biol Int. 41:1997;1153-1160.
    • (1997) Biochem Mol Biol Int , vol.41 , pp. 1153-1160
    • Sugihara, K.1    Kitamura, S.2    Tatsumi, K.3    Asahara, T.4    Dohi, K.5
  • 17
    • 0031007825 scopus 로고    scopus 로고
    • Purification and characterization of hepatic aldehyde oxidase in male and female mice
    • Yoshihara S., Tatsumi K. Purification and characterization of hepatic aldehyde oxidase in male and female mice. Arch Biochem Biophys. 338:1997;29-34.
    • (1997) Arch Biochem Biophys , vol.338 , pp. 29-34
    • Yoshihara, S.1    Tatsumi, K.2
  • 18
    • 0029025709 scopus 로고
    • Substrate specificity of human liver aldehyde oxidase toward substituted quinazolines and phthalazines: A comparison with hepatic enzyme from guinea pig, rabbit and baboon
    • Beedham C., Critchley D.J.P., Rance D.J. Substrate specificity of human liver aldehyde oxidase toward substituted quinazolines and phthalazines A comparison with hepatic enzyme from guinea pig, rabbit and baboon . Arch Biochem Biophys. 319:1995;481-490.
    • (1995) Arch Biochem Biophys , vol.319 , pp. 481-490
    • Beedham, C.1    Critchley, D.J.P.2    Rance, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.