Comparative cytogenetic study of spindle cell and pleomorphic leiomyosarcomas of soft tissues: A report from the CHAMP study group

Cancer Genetics and Cytogenetics

Volumn 116, Issue 1, 2000, Pages 66-73

  Mandahl, Nils ^a   Fletcher, Christopher D M ^b   Dal Cin, Paola ^b,c   De Wever, Ivo ^c   Mertens, Fredrik ^a   Mitelman, Felix ^a   Rosai, Juan ^d   Rydholm, Anders ^a   Sciot, Raf ^c   Tallini, Giovanni ^e   Van Den Berghe, Herman ^c   Vanni, Roberta ^c,f   Willén, Helena ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Dip Scienze Applicate Ai Biosistemi   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME LOSS; CLINICAL TRIAL; CYTOGENETICS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KARYOTYPE; LEIOMYOSARCOMA; MAJOR CLINICAL STUDY; MALE; METASTASIS; PLEOMORPHIC ADENOMA; PRIORITY JOURNAL; SPINDLE CELL;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOME ABERRATIONS; CHROMOSOME BREAKAGE; FEMALE; GENE AMPLIFICATION; HUMANS; KARYOTYPING; LEIOMYOSARCOMA; MALE; MIDDLE AGED; NEOPLASM METASTASIS; PLOIDIES;

EID: 0033990929     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(99)00114-4     Document Type: Article

References (16)

1. Mertens F., Rydholm A., Bauer H.F.C., Limon J., Nedoszytko B., Szadowska A., Willén H., Heim S., Mitelman F., Mandahl N. Cytogenetic findings in malignant peripheral nerve sheath tumors. Int J Cancer. 61:1995;793-798.
2. Mandahl N. Cytogenetics and molecular genetics of bone and soft tissue tumors. Adv Cancer Res. 69:1996;63-99.
3. Sreekantaiah C. The cytogenetic and molecular characterization of benign and malignant soft tissue tumors. Cytogenet Cell Genet. 82:1998;13-29.
4. Mertens F., Fletcher C.D.M., Dal Cin P., De Wever I., Mandahl N., Mitelman F., Rosai J., Rydholm A., Sciot R., Tallini G., Van den Berghe H., Vanni R., Willén H. Cytogenetic analysis of 46 pleomorphic soft tissue sarcomas and correlation with morphologic and clinical features. a report of the CHAMP study group Genes Chromosom Cancer. 22:1998;16-25.
5. Fletcher C.D.M., Dal Cin P., De Wever I., Mandahl N., Mertens F., Mitelman F., Rosai J., Rydholm A., Sciot R., Tallini G., van den Berghe H., Vanni R., Willén H. Correlation between clinicopathological features and karyotype in spindle cell sarcomas. a report of 130 cases from the CHAMP study group Am J Pathol. 154:1999;1841-1847.
6. Nilbert M., Mandahl N., Heim S., Rydholm A., Willén H., Åkerman M., Mitelman F. Chromosome abnormalities in leiomyosarcomas. Cancer Genet Cytogenet. 34:1988;209-218.
7. Örndal C., Rydholm A., Willén H., Mitelman F., Mandahl N. Cytogenetic intratumor heterogeneity in soft tissue tumors. Cancer Genet Cytogenet. 78:1994;127-137.
8. Dal Cin P., Sciot R., Fletcher C.D.M., Samson I., de Vos R., Mandahl N., Willén H., Larsson O., Van den Berghe H. Inflammatory leiomyosarcoma may be characterized by specific near-haploid chromosome changes. J Pathol. 185:1998;112-115.
9. Limon J., Dal Cin P., Sandberg A.A. Application of long term collagenase disaggregation for the cytogenetic analysis of human solid tumors. Cancer Genet Cytogenet. 23:1986;305-313.
10. Mandahl N., Heim S., Arheden K., Rydholm A., Willén H., Mitelman F. Three major cytogenetic subgroups can be identified among chromosomally abnormal solitary lipomas. Hum Genet. 79:1988;203-208.
11. ISCN (1995): An International System for Human Cytogenetic Nomenclature. F Mitelman, ed. S. Karger, Basel.
12. Mandahl N., Baldetorp B., Fernö M., Åkerman M., Rydholm A., Heim S., Willén H., Killander D., Mitelman F. Comparative cytogenetic and DNA flow cytometric analysis of 150 bone and soft-tissue tumors. Int J Cancer. 53:1993;358-364.
13. Mitelman F. Catalog of Chromosome Aberrations in Cancer. 6th Ed:1998;John Wiley & Sons, New York.
14. El-Rifai W., Sarlomo-Rikala M., Knuutila S., Miettinen M. DNA copy number changes in development and progression in leiomyosarcomas of soft tissues. Am J Pathol. 153:1998;985-990.
15. Boghosian L., Dal Cin P., Turc-Carel C., Rao U., Karakousis C., Jani Sait S., Sandberg A.A. Three possible cytogenetic subgroups of leiomyosarcoma. Cancer Genet Cytogenet. 43:1989;39-49.
16. Bardi G., Johansson B., Pandis N., Heim S., Mandahl N., Bak-Jensen E., Fredriksen H., Andrén-Sandberg Å, Mitelman F. Recurrent chromosome aberrations in abdominal smooth muscle tumors. Cancer Genet Cytogenet. 62:1992;43-46.