Primary response of naive CD4+ T cells to amino acid-substituted analogs of an antigenic peptide can show distinct activation patterns: Th1- and Th2-type cytokine secretion, and helper activity for antibody production without apparent cytokine secretion

FEBS Letters

Volumn 465, Issue 1, 2000, Pages 28-33

  Ise, Wataru ^a   Totsuka, Mamoru ^a   Takato, Rumi ^a   Hachimura, Satoshi ^a   Sato, Takehito ^b   Ametani, Akio ^a   Kumagai, Yoshihiro ^c   Habu, Sonoko ^b   Kaminogawa, Shuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Altered peptide ligand; Antibody production; Cytokine production; Naive CD4+ T cell; Primary response; Th1 Th2

Indexed keywords

OVALBUMIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL DIFFERENTIATION; CELL STIMULATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; IMMUNE RESPONSE; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; T LYMPHOCYTE; TH1 CELL; TH2 CELL; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; ANTIGENS; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; COCULTURE TECHNIQUES; HISTOCOMPATIBILITY ANTIGENS CLASS II; INTERLEUKIN-2; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; TH1 CELLS; TH2 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

MUS MUSCULUS;

EID: 0033989930     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01716-0     Document Type: Article

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