Persistence of infectious herpes simplex virus type 2 in the nervous system in mice after antiviral chemotherapy

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 1, 2000, Pages 97-102

  Thackray, Alana M ^a   Field, Hugh J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FAMCICLOVIR; VALACICLOVIR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; FEMALE; HERPES SIMPLEX VIRUS 2; HERPES VIRUS INFECTION; MOUSE; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL;

EID: 0033989896     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.1.97-102.2000     Document Type: Article

References (30)

1. Awan, A. R., J. Harmenberg, O. Flink, and H. J. Field. 1998. Combinations of antiviral and anti-inflammatory preparations for the topical treatment of herpes simplex virus assessed using a murine zosteriform infection model. Antivir. Chem. Chemother. 9:19-24.
2. Beauchamp, L. M., G. F. Orr, P. de Miranda, T. Burnette, H. J. Schaeffer, and T. A. Krenitsky. 1992. Amino acid ester prodrugs of acyclovir. Antivir. Chem. Chemother. 3:157-163.
3. Bernstein, D. I., M. A. Lovett, and Y. J. Bryson. 1984. The effects of acyclovir on antibody response to herpes simplex virus in primary genital herpetic infections. J. Infect. Dis. 150:7-13.
4. Cabrera, C. V., C. Wohlenberg, H. Openshaw, M. Rey-Mendez, A. Puga, and A. L. Notkins. 1980. Herpes simplex virus DNA sequences in the CNS of latently infected mice. Nature 288:288-290.
5. Cook, M. L., V. B. Bastone, and J. G. Stevens. 1974. Evidence that neurons harbor latent herpes simplex virus. Infect. Immun. 9:946-951.
6. Erlich, K. S., L. Hauer, and J. Mills. 1988. Effects of long-term acyclovir chemosuppression on serum IgG antibody to herpes simplex virus. J. Med. Virol. 26:33-39.
7. Field, H. J., D. Tewari, D. Sutton, and A. M. Thackray. 1995. Comparison of efficacies of famciclovir and valaciclovir against herpes simplex virus type 1 in a murine immunosuppression model. Antimicrob. Agents Chemother. 39: 1114-1119.
8. Field, H. J., and A. M. Thackray. 1995. The effects of delayed-onset chemotherapy using famciclovir or valaciclovir in a murine immunosuppression model for HSV-1. Antivir. Chem. Chemother. 6:210-216.
9. Field, H. J., and P. Wildy. 1978. The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice. J. Hyg. Camb. 81:267-277.
10. Harnden, M. R., R. L. Jarvest, M. R. Boyd, D. Sutton, and R. A. Vere Hodge. 1989. Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved absorption properties. J. Med. Chem. 32:1738-1743.
11. Hill, T. J., H. J. Field, and W. A. Blyth. 1975. Acute and recurrent infection with herpes simplex virus in the mouse: a model for studying latency and recurrent disease. J. Gen. Virol. 28:341-353.
12. Kawana, T., M. Hashido and Y. Koizumi. 1995. Class-specific antibody response in acyclovir-treated and adenine arabinoside-treated patients with primary genital herpes simplex virus infection. Microbiol. Immunol. 39:795-799.
13. King, D. P., Y. Zhao, A. M. Sangoram, L. D. Wilsbacher, M. Tanaka, M. P. Antoch, T. D. L. Steeves, M. H. Vitaterna, J. M. Kornhauser, P. L. Lowrey, F. W. Turek, and J. S. Takahashi. 1997. Positional cloning of the mouse circadian clock gene. Cell 89:641-653.
14. Kraft, M., and R. J. Martin. 1995. Chronobiology and chronotherapy in medicine. Dis. Monogr. 41:501-575.
15. Kristensson, K., E. Lycke, and J. Sjöstrand. 1974. Spread of herpes simplex virus in peripheral nerves. Acta Neuropathol. 17:44-53.
16. Li, Z., H. Sato, Y. Fukuda, M. Kurokawa, S. Kageyama, T. Kawana, and K. Shiraki. 1999. Acyclovir treatment of skin lesions results in immune deviation in mice infected cutaneously with herpes simplex virus. Antivir. Chem. Chemother. 10:251-257.
17. McLennan, J. L., and G. Darby. 1980. Herpes simplex virus latency: the cellular location of virus in dorsal root ganglia and the fate of the infected cell following virus activation. J. Gen. Virol. 51:233-243.
18. Sawtell, N. M., and R. L. Thompson. 1992. Rapid in vivo reactivation of herpes simplex virus in latently infected murine ganglionic neurons after transient hyperthermia. J. Virol. 66:2150-2156.
19. Scheck, A. C., B. Wigdahl, E. DeClereq, and F. Rapp. 1986. Prolonged herpes simplex virus latency in vitro after treatment of infected cells with acyclovir and human leukocyte interferon. Antimicrob. Agents Chemother. 29:589-593.
20. Stanberry, L. R. 1992. Pathogenesis of herpes simplex virus infection and animal models for its study. Curr. Top. Microbiol. Immunol. 179:15-30.
21. Steiner, I., and P. G. E. Kennedy. 1995. Herpes simplex virus latent infection in the nervous system. J. Neurovirol. 1:19-29.
22. Stevens, J. G., and M. L. Cook. 1971. Latent herpes simplex virus in spinal ganglia of mice. Science 173:843-845.
23. Thackray, A. M., and H. J. Field. 1996. Differential effects of famciclovir and valaciclovir on the pathogenesis of herpes simplex virus in a murine infection model including reactivation from latency. J. Infect. Dis. 173:291-299.
24. Thackray, A. M., and H. J. Field. 1996. Comparison of effects of famciclovir and valaciclovir on pathogenesis of herpes simplex virus type 2 in a murine infection model. Antimicrob. Agents Chemother. 40:846-851.
25. Thackray, A. M., and H. J. Field. 1997. The influence of cyclosporin immunosuppression on the efficacy of famciclovir or valaciclovir chemotherapy studied in a murine herpes simplex virus type 1 infection model. Antivir. Chem. Chemother. 8:317-326.
26. Thackray, A. M., and H. J. Field. 1998. Famciclovir and valaciclovir differ in the prevention of herpes simplex virus type 1 latency in mice: a quantitative study. Antimicrob. Agents Chemother. 42:1555-1562.
27. Thouless, M. E. 1972. Serological properties of thymidine kinase produced in cells infected with type 1 or type 2 herpes virus. J. Gen. Virol. 71:307-315.
28. Wagner, E. K., and D. C. Bloom. 1997. Experimental investigation of herpes simplex virus latency. Clin. Microbiol. Rev. 10:419-443.
29. Wigdahl, B. L., A. C. Scheck, E. DeClercq, and F. Rapp. 1982. High efficiency latency and activation of herpes simplex virus in human cells. Science 217: 1145-1146.
30. Wildy, P., H. J. Field, and A. A. Nash. 1982. Classical herpes latency revisited, p. 133-167. In B. W. J. Mahy, A. C. Minson, and G. K. Darby (ed.), Virus persistence. Society for General Microbiology Symposium 33. Cambridge University Press, Cambridge, United Kingdom.