Effect of proton pump inhibitor alone or in combination with clarithromycin on mycobacterial growth in human alveolar macrophages

FEMS Microbiology Letters

Volumn 182, Issue 1, 2000, Pages 69-72

  Suzuki, Katsuhiro ^a   Tsuyuguchi, Kazunari ^a   Matsumoto, Hisako ^a   Niimi, Akio ^a   Tanaka, Eisaku ^a   Amitani, Ryoichi ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Acidic phagosome; Clarithromycin; Human alveolar macrophage; Mycobacterium tuberculosis; Proton pump inhibitor

Indexed keywords

CLARITHROMYCIN; OMEPRAZOLE; PROTON PUMP INHIBITOR;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BIOLOGICAL MODEL; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; MYCOBACTERIOSIS; MYCOBACTERIUM; MYCOBACTERIUM AVIUM; MYCOBACTERIUM INTRACELLULARE; MYCOBACTERIUM TUBERCULOSIS; PHAGOSOME; PRIORITY JOURNAL; TUBERCULOSIS;

ADULT; ANTI-BACTERIAL AGENTS; CELL SURVIVAL; CELLS, CULTURED; CLARITHROMYCIN; HUMANS; HYDROGEN-ION CONCENTRATION; MACROPHAGES, ALVEOLAR; MIDDLE AGED; MYCOBACTERIUM; OMEPRAZOLE; PHAGOSOMES; PROTON PUMPS;

MYCOBACTERIUM; MYCOBACTERIUM AVIUM; MYCOBACTERIUM INTRACELLULARE; MYCOBACTERIUM TUBERCULOSIS;

EID: 0033989837     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(99)00571-6     Document Type: Article

References (21)

1. Bhardawaj V.C., Colston P.D. The processing and presentation of mycobacterial antigens by human monocytes. Eur. J. Immunol. 18:1988;691-696.
2. Armstrong J.A., Hart P.D. Response of cultured macrophages to Mycobacterium tuberculosis with observations on fusion of lysosomes with phagosomes. J. Exp. Med. 134:1971;713-740.
3. Crowle A.J., May M.H. Inhibition of tubercle bacilli in cultured human macrophages by chloroquin used alone and in combination with streptomycin, isoniazid, pyrazinamide, and two metabolites of vitamin D3. Infect. Immun. 34:1990;2217-2222.
4. Crowle A.J., Dahl R., Ross E., May M.H. Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic. Infect. Immun. 59:1991;1823-1831.
5. Gordon A.H., Hart P.D., Young M.R. Ammonia inhibits phagosome-lysosome fusion in macrophages. Nature (London). 286:1980;79-80.
6. Sturgill-Koszycki S., Schlesinger P.H., Chakraborty P., Haddix P.L., Collins H.L., Fok A.G., Allen R.D., Gluck S.L., Heuser J., Russel D.G. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science. 263:1994;678-681.
7. Forgac M. Structure and function of vacuolar class of ATP-driven proton pumps. Physiol. Rev. 69:1989;765-796.
8. +)-ATPase from clathrin-coated vesicles. Eur. J. Cell Biol. 56:1991;19-33.
9. Mellman I. The importance of being acid: the role of acidification in intracellular membrane traffic. J. Exp. Biol. 172:1992;39-45.
10. Maton P.N. Omeprazole. New. Engl. J. Med. 324:1991;965-975.
11. Truffot-Pernot C., Ji B., Grosset J.H. Effect of pH on the in vitro potency of clarithromycin against Mycobacterium avium complex. Antimicrob. Agents Chemother. 35:1991;1677-1678.
12. Truffot-Pernot C., Lounis N., Grosset J.H., Ji B. Clarithromycin is inactive against Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 39:1995;2827-2828.
13. Suzuki K., Yamamoto T., Sato A., Murayama T., Amitani R., Yamamoto K., Kuze F. Lipopolysaccharide primes human alveolar macrophages for enhanced release of superoxide anion and leukotrien B4: Self-limitations of the priming response with protein synthesis. Am. J. Respir. Cell. Mol. Biol. 8:1993;500-508.
14. Suzuki K., Tsuyuguchi K., Matsumoto H., Yamamoto T., Hashimoto T., Tanaka E., Amitani R., Kuze F. Activity of KRM1648 or rifabutin alone or in combination with clarithromycin against Mycobacterium avium complex in human alveolar macrophages. Int. J. Tuberc. Lung Dis. 1:1997;460-467.
15. Wroblewski F., LaDue J.S. Lactic dehydrogenase activity in blood. Proc. Soc. Exp. Biol. Med. 90:1955;210-213.
16. Mackaness G.B. The action of drugs on intracellular tubercle bacilli. J. Pathol. Bacteriol. 64:1952;429-446.
17. Mackaness G.B. The intracellular activation of pyrazinamide and nicotinamide. Am. Rev. Tuberc. Pulm. Dis. 74:1956;718-726.
18. McDermott W., Tompsett R. Activation of pyrazinamide and nicotinamide in acidic environments in vitro. Am. Rev. Tuberc. 70:1954;748-754.
19. Cavalieri S.J., Biehle J.R., Sanders W.E.Jr. Synergistic activities of clarithromycin and antituberculous drugs against multidrug-resistant Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 39:1995;1542-1545.
20. Luna-Herrera J., Reddy V.M., Daneluzzi D., Gangadharam P.R.J. Antituberculosis activity of clarithromycin. Antimicrob. Agents Chemother. 39:1995;2692-2695.
21. Mor N., Esfandiari A. Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages. Antimicrob. Agents Chemother. 41:1997;2035-2036.