Longitudinal analysis of the segregation of mtDNA mutations in heteroplasmic individuals

Journal of the Neurological Sciences

Volumn 172, Issue 1, 2000, Pages 1-6

  Howell, Neil ^a   Ghosh, Soumitra S ^b   Fahy, Eoin ^b   Bindoff, Laurence A ^c  

^a Dept Hum Biol Chem Genet U ^*  (United States)

^b Migenix Inc   (United States)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Heteroplasmy; Leber hereditary optic neuropathy; Longitudinal analysis; Mitochondrial DNA; Mitochondrial genetics

Indexed keywords

MITOCHONDRIAL DNA;

ALLELE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; GENE MUTATION; GENE SEGREGATION; GENETIC POLYMORPHISM; GENETIC SELECTION; HEREDITARY OPTIC ATROPHY; HETEROZYGOSITY; HUMAN; HUMAN CELL; PEDIGREE; PRIORITY JOURNAL; SEGREGATION ANALYSIS;

DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; GENETIC HETEROGENEITY; HUMANS; LONGITUDINAL STUDIES; OPTIC ATROPHIES, HEREDITARY; POLYMORPHISM, GENETIC;

EID: 0033989668     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(99)00207-5     Document Type: Article

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