Rapid, real-time sampling of R-84760 in blood by in vivo microdialysis with tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 21, Issue 6, 2000, Pages 1233-1242

  Kobayashi, Nobuhiro ^a   Kazui, Miho ^a   Ikeda, Toshihiko ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Microdialysis tandem mass spectrometry; R 84760, in vivo protein binding; Rat whole blood; Real time analysis

Indexed keywords

ANALGESIC AGENT; R 84760; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG PROTEIN BINDING; FLOW INJECTION ANALYSIS; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SAMPLING; TANDEM MASS SPECTROMETRY;

ANALGESICS; ANIMALS; CALIBRATION; INFUSIONS, INTRAVENOUS; MASS SPECTROMETRY; MICRODIALYSIS; PYRROLIDINES; RATS; THIAZINES;

EID: 0033988677     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(99)00242-3     Document Type: Article

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