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Volumn 11, Issue 1, 2000, Pages 37-45

From genotype to phenotype: Behavior of the transgenic rat TGR(mRen2)27 as an example

Author keywords

Anxiety; Behavior; Microdialysis; Phenotype; TGR(mRen2)27; Transgenic rat

Indexed keywords

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; SEROTONIN;

EID: 0033988188     PISSN: 03341763     EISSN: None     Source Type: Journal    
DOI: 10.1515/REVNEURO.2000.11.1.37     Document Type: Conference Paper
Times cited : (4)

References (44)
  • 1
    • 0030735649 scopus 로고    scopus 로고
    • Ethopharmacological analysis of behaviour of rats using variations of the elevated plus-maze
    • Anseloni VZ, Brandao ML. Ethopharmacological analysis of behaviour of rats using variations of the elevated plus-maze. Behav Pharmacol 1997; 8: 533-540.
    • (1997) Behav Pharmacol , vol.8 , pp. 533-540
    • Anseloni, V.Z.1    Brandao, M.L.2
  • 2
    • 0031041560 scopus 로고    scopus 로고
    • Behavioral effects of angiotensin II microinjected into CA1 hippocampal area
    • Belcheva I, Georgiev V, Chobanova M, Hadjiivanova C. Behavioral effects of angiotensin II microinjected into CA1 hippocampal area. Neuropeptides 1997; 31: 60-64.
    • (1997) Neuropeptides , vol.31 , pp. 60-64
    • Belcheva, I.1    Georgiev, V.2    Chobanova, M.3    Hadjiivanova, C.4
  • 3
    • 0024423121 scopus 로고
    • Effects of angiotensin II and its fragments: Angiotensin II(3-8)-hexapeptide and angiotensin II(4-8)-pentapeptide on retrieval in passive avoidance situation in rats chronically treated with ethanol
    • Borawska M, Kupryszewski G, Witczuk B, Wisniewski K. Effects of angiotensin II and its fragments: angiotensin II(3-8)-hexapeptide and angiotensin II(4-8)-pentapeptide on retrieval in passive avoidance situation in rats chronically treated with ethanol. Pol J Pharmacol Pharm 1989; 41: 227-230.
    • (1989) Pol J Pharmacol Pharm , vol.41 , pp. 227-230
    • Borawska, M.1    Kupryszewski, G.2    Witczuk, B.3    Wisniewski, K.4
  • 4
    • 0028305932 scopus 로고
    • Social interaction increases 5-HT release and cAMP efflux in the rat ventral hippocampus in vivo
    • Cadogan AK, Kendall DA, Fink H, Marsden CA. Social interaction increases 5-HT release and cAMP efflux in the rat ventral hippocampus in vivo. Behav Pharmacol 1994; 5: 299-305.
    • (1994) Behav Pharmacol , vol.5 , pp. 299-305
    • Cadogan, A.K.1    Kendall, D.A.2    Fink, H.3    Marsden, C.A.4
  • 6
    • 0029925695 scopus 로고    scopus 로고
    • Unusual behavioral phenotypes of inbred mouse strains
    • Crawley J. Unusual behavioral phenotypes of inbred mouse strains. Trends Neurosci 1996; 19: 181-182.
    • (1996) Trends Neurosci , vol.19 , pp. 181-182
    • Crawley, J.1
  • 7
    • 0030012143 scopus 로고    scopus 로고
    • Gene-targeting studies: New methods, old problems
    • Crusio WE. Gene-targeting studies: new methods, old problems. Trends Neurosci 1996; 19: 186-187.
    • (1996) Trends Neurosci , vol.19 , pp. 186-187
    • Crusio, W.E.1
  • 8
    • 0027932914 scopus 로고
    • Ethopharmacological analysis of rat behavior on the elevated plus-maze
    • Cruz APM, Frei F, Graeff FG. Ethopharmacological analysis of rat behavior on the elevated plus-maze. Pharmacol Biochem Behav 1994; 49: 171-176.
    • (1994) Pharmacol Biochem Behav , vol.49 , pp. 171-176
    • Cruz, A.P.M.1    Frei, F.2    Graeff, F.G.3
  • 9
    • 0017885962 scopus 로고
    • Hydrolysis of enkephalin by cultured human endothelian cells and by purified peptidyl dipeptidase
    • Erdös EG, Johnson AR, Boyden NT. Hydrolysis of enkephalin by cultured human endothelian cells and by purified peptidyl dipeptidase. Biochem Pharmacol 1978; 27: 843-848.
    • (1978) Biochem Pharmacol , vol.27 , pp. 843-848
    • Erdös, E.G.1    Johnson, A.R.2    Boyden, N.T.3
  • 10
    • 0003143197 scopus 로고
    • Behavioural detection of anxiolytic action
    • Elliot JM, Heal DJ, Marsden CA, eds. New York: John Wiley & Sons
    • File SE. Behavioural detection of anxiolytic action. In: Elliot JM, Heal DJ, Marsden CA, eds. Experimental Approaches to Anxiety and Depression. New York: John Wiley & Sons, 1992; 25-43.
    • (1992) Experimental Approaches to Anxiety and Depression , pp. 25-43
    • File, S.E.1
  • 11
    • 0027729919 scopus 로고
    • The interplay between learning and anxiety in the elevated plus-maze
    • File SE. The interplay between learning and anxiety in the elevated plus-maze. Behav Brain Res 1993; 58: 199-102.
    • (1993) Behav Brain Res , vol.58 , pp. 199-1102
    • File, S.E.1
  • 13
    • 0029940557 scopus 로고    scopus 로고
    • Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?
    • Gerlai R. Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci 1996; 19: 177-181.
    • (1996) Trends Neurosci , vol.19 , pp. 177-181
    • Gerlai, R.1
  • 14
    • 0029940557 scopus 로고    scopus 로고
    • Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype? Reply
    • Gerlai R. Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Reply. Trends Neurosci 1996; 19: 472.
    • (1996) Trends Neurosci , vol.19 , pp. 472
    • Gerlai, R.1
  • 15
    • 0025072060 scopus 로고
    • Effect of angiotensin II on the Vogel conflict paradigm and on the content of dopamine and noradrenaline in rat brain
    • Georgiev V, Stancheva S, Kambourova T, Getova D. Effect of angiotensin II on the Vogel conflict paradigm and on the content of dopamine and noradrenaline in rat brain. Acta Physiol Pharmacol Bulg 1990; 16: 32-37.
    • (1990) Acta Physiol Pharmacol Bulg , vol.16 , pp. 32-37
    • Georgiev, V.1    Stancheva, S.2    Kambourova, T.3    Getova, D.4
  • 17
    • 0026767755 scopus 로고
    • Antianxiety properties of the angiotensin II antagonist, DUP 753, in the rat using the elevated plus-maze
    • Kaiser FC, Palmer GC, Wallace AV, Carr RD, Fraser Rae L, Hallam C. Antianxiety properties of the angiotensin II antagonist, DUP 753, in the rat using the elevated plus-maze. NeuroReport 1992; 3: 922-924.
    • (1992) NeuroReport , vol.3 , pp. 922-924
    • Kaiser, F.C.1    Palmer, G.C.2    Wallace, A.V.3    Carr, R.D.4    Fraser Rae, L.5    Hallam, C.6
  • 18
    • 0030995485 scopus 로고    scopus 로고
    • Central serotonergic systems in the spontaneously hypertensive and Lewis rat strains that differ in the elevated plus-maze test of anxiety
    • Kulikov A, Aguerre S, Berton O, Ramos A, Mormede P, Chaouloff F. Central serotonergic systems in the spontaneously hypertensive and Lewis rat strains that differ in the elevated plus-maze test of anxiety. J Pharmacol Exp Ther 1997; 281: 775-784.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 775-784
    • Kulikov, A.1    Aguerre, S.2    Berton, O.3    Ramos, A.4    Mormede, P.5    Chaouloff, F.6
  • 19
    • 0029950077 scopus 로고    scopus 로고
    • The hypertensive Ren-2 transgenic rat TGR (mREN2)27 in hypertension research. Characteristics and functional aspects
    • Langheinrich M, Lee MA, Böhm M, Pinto YM, Ganten D, Paul M. The hypertensive Ren-2 transgenic rat TGR (mREN2)27 in hypertension research. Characteristics and functional aspects. Am J Hypertens 1996; 9: 506-512.
    • (1996) Am J Hypertens , vol.9 , pp. 506-512
    • Langheinrich, M.1    Lee, M.A.2    Böhm, M.3    Pinto, Y.M.4    Ganten, D.5    Paul, M.6
  • 20
    • 0030011889 scopus 로고    scopus 로고
    • Mice, gene targeting and behavior: More than just genetic background
    • Lathe R. Mice, gene targeting and behavior: more than just genetic background. Trends Neurosci 1996; 19: 183-186.
    • (1996) Trends Neurosci , vol.19 , pp. 183-186
    • Lathe, R.1
  • 21
    • 0000561070 scopus 로고    scopus 로고
    • Physiological characterization of the hypertensive transgenic rat TGR(mREN2)27
    • Lee MA, Böhm M, Paul M, Bader M, Ganten U, Ganten D. Physiological characterization of the hypertensive transgenic rat TGR(mREN2)27. Am J Physiol 1996; 270: E919-929.
    • (1996) Am J Physiol , vol.270
    • Lee, M.A.1    Böhm, M.2    Paul, M.3    Bader, M.4    Ganten, U.5    Ganten, D.6
  • 22
    • 0023255981 scopus 로고
    • The use of a plus-maze to measure anxiety in the mouse
    • Lister RG. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology 1987; 92: 180-185.
    • (1987) Psychopharmacology , vol.92 , pp. 180-185
    • Lister, R.G.1
  • 25
    • 0025239301 scopus 로고
    • Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene
    • Mullins JJ, Peters J, Ganten D. Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature 1990; 344: 541-544.
    • (1990) Nature , vol.344 , pp. 541-544
    • Mullins, J.J.1    Peters, J.2    Ganten, D.3
  • 26
    • 0022374863 scopus 로고
    • Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
    • Fellow S, Chopin Ph, File SE, Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Meth 1985; 14: 149-167.
    • (1985) J Neurosci Meth , vol.14 , pp. 149-167
    • Fellow, S.1    Chopin, Ph.2    File, S.E.3    Briley, M.4
  • 27
    • 0023161147 scopus 로고
    • Functions of angiotensin in the central nervous system
    • Phillips MI Functions of angiotensin in the central nervous system. Ann Rev Physiol 1987; 49: 413-435.
    • (1987) Ann Rev Physiol , vol.49 , pp. 413-435
    • Phillips, M.I.1
  • 28
    • 0027389222 scopus 로고
    • Effect of diazepam on cortical 5-HT release and behaviour in the guinea-pig on exposure to the elevated plus maze
    • Rex A, Marsden CA, Fink H. Effect of diazepam on cortical 5-HT release and behaviour in the guinea-pig on exposure to the elevated plus maze. Psychopharmacology 1993; 110: 490-496.
    • (1993) Psychopharmacology , vol.110 , pp. 490-496
    • Rex, A.1    Marsden, C.A.2    Fink, H.3
  • 29
    • 0002358097 scopus 로고
    • The elevated plus-maze: Pharmacology, methodology and ethology
    • Cooper SJ, Hendrie CA, eds. New York: John Wiley & Sons Ltd.
    • Rodgers RJ, Cole JC. The elevated plus-maze: Pharmacology, methodology and ethology. In: Cooper SJ, Hendrie CA, eds. Ethology and Pharmacology. New York: John Wiley & Sons Ltd., 1994; 9-44.
    • (1994) Ethology and Pharmacology , pp. 9-44
    • Rodgers, R.J.1    Cole, J.C.2
  • 31
    • 0029947917 scopus 로고    scopus 로고
    • Effects of the selective angiotensin II receptor antagonists losartan and PD 123177 in animal models of anxiety and memory
    • Shepherd J, Bill DJ, Dourish CT, Grewal SS, McLenachan A, Stanhope KJ. Effects of the selective angiotensin II receptor antagonists losartan and PD 123177 in animal models of anxiety and memory. Psychopharmacology 1996; 126: 206-218.
    • (1996) Psychopharmacology , vol.126 , pp. 206-218
    • Shepherd, J.1    Bill, D.J.2    Dourish, C.T.3    Grewal, S.S.4    McLenachan, A.5    Stanhope, K.J.6
  • 33
    • 0024840099 scopus 로고
    • The SHR exhibits less "anxiety" but increased sensitivity to the anticonflict effect of clonidine compared to normotensive controls
    • Söderpalm B. The SHR exhibits less "anxiety" but increased sensitivity to the anticonflict effect of clonidine compared to normotensive controls. Pharmacol Toxicol 1989; 65: 381-386.
    • (1989) Pharmacol Toxicol , vol.65 , pp. 381-386
    • Söderpalm, B.1
  • 34
    • 0025912598 scopus 로고
    • Characterization and development of angiotensin II receptor subtypes (AT1 and AT2) in rat brain
    • Tsutsumi K, Saavedra JM. Characterization and development of angiotensin II receptor subtypes (AT1 and AT2) in rat brain. Am J Physiol 1991; 261: R209-R216.
    • (1991) Am J Physiol , vol.261
    • Tsutsumi, K.1    Saavedra, J.M.2
  • 36
    • 0033152535 scopus 로고    scopus 로고
    • Hippocampal 5-HT and NE release in the transgenic rat TGR(mRen2)27 related to behavior on the elevated plus maze
    • Voigt JP, Rex A, Sohr R, Fink H. Hippocampal 5-HT and NE release in the transgenic rat TGR(mRen2)27 related to behavior on the elevated plus maze. Eur Neuropsychopharmacol 1999; 9: 279-285.
    • (1999) Eur Neuropsychopharmacol , vol.9 , pp. 279-285
    • Voigt, J.P.1    Rex, A.2    Sohr, R.3    Fink, H.4
  • 39
    • 0026440925 scopus 로고
    • Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze
    • Wright IK, Upton N, Marsden CA. Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze. Psychopharmacology 1992; 109: 338-346.
    • (1992) Psychopharmacology , vol.109 , pp. 338-346
    • Wright, I.K.1    Upton, N.2    Marsden, C.A.3
  • 41
    • 0028894823 scopus 로고
    • Brain angiotensin receptor subtypes AT-1, AT-2, and AT-4 and their functions
    • Wright JW, Harding JW. Brain angiotensin receptor subtypes AT-1, AT-2, and AT-4 and their functions. Regul Peptides 1995; 59: 269-295.
    • (1995) Regul Peptides , vol.59 , pp. 269-295
    • Wright, J.W.1    Harding, J.W.2
  • 42
    • 0026674166 scopus 로고
    • Impaired learning and memory in mature hypertensive rats
    • Wyss JM, Fisk G, van Groen T. Impaired learning and memory in mature hypertensive rats. Brain Res 1992; 592: 135-140.
    • (1992) Brain Res , vol.592 , pp. 135-140
    • Wyss, J.M.1    Fisk, G.2    Van Groen, T.3
  • 43
    • 0021043072 scopus 로고
    • A new feature of angiotensin-converting enzyme in the brain: Hydrolysis of substance P
    • Yokosawa H, Endo S, Ogura Y, Ishii S. A new feature of angiotensin-converting enzyme in the brain: hydrolysis of substance P. Biochem Biophys Res Comm 1983; 116: 735-742.
    • (1983) Biochem Biophys Res Comm , vol.116 , pp. 735-742
    • Yokosawa, H.1    Endo, S.2    Ogura, Y.3    Ishii, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.