The isolation and characterization of a peptide that alters sodium channels from Buthus martensii Karsch

Toxicon

Volumn 38, Issue 5, 2000, Pages 645-660

  Hahin, Richard ^a   Chen, Ziyi ^a   Reddy, Giridher ^b  

^a NORTHERN ILLINOIS UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTOXIN; SCORPION VENOM; SODIUM CHANNEL;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN ISOLATION; PROTEIN PURIFICATION; SCORPION; SEQUENCE HOMOLOGY;

ACTION POTENTIALS; AMINO ACID SEQUENCE; ANIMALS; ANURA; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NEUROTOXINS; PEPTIDES; SCIATIC NERVE; SCORPION VENOMS; SCORPIONS; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM CHANNELS;

ANIMALIA; ANURA; BUTHUS; INSECTA; MESOBUTHUS MARTENSII; SCORPIONES;

EID: 0033986920     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(99)00180-4     Document Type: Article

References (19)

1. Catterall W.A. Neurotoxins that act on voltage-sensitive sodium channel in excitable membranes. Annu. Rev. Pharmacol. Toxicol. 20:1980;15-43.
2. Catterall W.A. Molecular properties of voltage sensitive sodium channels. Annu. Rev. Biochem. 55:1986;953-985.
3. Catterall W.A., Beress L. Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophore. J. Biol. Chem. 253:1978;7393-7396.
4. + ionophore in neuroblastoma cells. Biochem. Biophys. Res. Commun. 83:1978;1525-1530.
5. Fontecilla-Camps J.C., Almassy R.J., Suddath F.L., Watt D.D., Bugg C.E. Three-dimensional structure of a protein from scorpion venom: A new structural class of neurotoxins. Proc. Natl Acad. Sci. 77:1980;6496-6500.
6. Hahin R., Strichartz G. Effects of duterium oxide on the rate and dissociation constants for saxotoxin and tetrototoxin action. J. Gen. Physiol. 78:1981;113-139.
7. Kessler H., Matter H., Gemmecker G., Diehl H.J., Isernia C., Mronga S. The pseudo-beta I-turn. A new structural motif with cis peptide bond in cyclic hexapeptides. Int. J. Pepp. Protein Res. 43:1994;47-61.
8. Kopeyan C., Martinez G., Rochat H. Amino acid sequence of neurotoxin V from the scorpion Leiurus quinquestriatus quinquestriatusrm. FEBS Lett. 89:1978;54-58.
9. Martin M.F., Rochat H. Purification of 13 toxins active on mice from the venom of the north African scorpion Buthus occitanus tumetanus. Toxicon. 22:1984;279-291.
10. Martin A.C., Toda K., Stirk H.J., Thornton J.M. Long loops in proteins. Protein Eng. 8:1995;1093-1101.
11. Martin-Eauclaire M.S., Courard S. Scorpion Neurotoxins: Effects and Mechanisms. Chang L.W., Dyer R.S. Handbook of Neurotoxicology. 1995;683-716 Dekker, New York.
12. Miranda F., Kopeyan C., Rochat H., Rochat C., Lissitzky S. Purification of animal neurotoxins. Isolation and characterization of 11 neurotoxins from the venoms of the scorpion Androctonus australis Hector, Buthus occitanus tunetanus, and Leiurus quinquestriatus quinquestriatus. European J. Biochem. 16:1970;514-523.
13. Muller G., Gurrath N., Kurz M., Kessler H. Beta VI turns in peptides and proteins, a model peptide mimicry. Proteins. 15:1993;235-251.
14. Rochat H., Rochat C., Sampieri F., Miranda F., Lissitzky S. The amino acid sequence of neurotoxin II of Androctonus australis Hector. Eur. J. Biochem. 28:1972;381-388.
15. Rogers J.C., Qu Y., Tanada T.M., Scheuer T., Catterall W.A. Molecular determinants of high affinity binding of alpha scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain 4IV of the sodium channel alpha subunit. J. Biol. Chem. 271:1996;15950-15962.
16. Rosso J.P., Rochat H. Characterization of 10 proteins from the venom of the Moroccan scorpion Androctonus mauretanicus mauretanicus, six of which are toxic to the mouse. Toxicon. 23:1985;113-125.
17. Segalas I., Thai R., Menez R., Zita Z. A particularly labile Asp-Pro bond in the green mamba muscarinic toxin MTX2. Effect of protein confirmation on the rate of cleavage. FEBS Lett. 371:1995;171-175.
18. Vargas O., Gregoire J., Martin M-F., Bechis G., Rochat H. Toxicon. 20:1982;79-79.
19. Volkova T.M., Garsia A.F., Telezhinskaia I.M., Potapenko N.A., Grishin E.V. Neurotoxins from the venom of the central Asian scorpion Buthus eupeus. Bioorg. Khim. 11:1985;1445-1456.