Management of heparin-associated thrombocytopenia in pregnancy with subcutaneous r-hirudin

Gynecologic and Obstetric Investigation

Volumn 49, Issue 1, 2000, Pages 67-69

  Huhle, G ^a   Geberth, M ^b   Hoffmann, U ^b   Heene, D L ^b   Harenberg, J ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NONE

Author keywords

Heparin induced thrombocytopenia; Hirudin; Pregnancy

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; DALTEPARIN; DANAPAROID; HEPARIN; LEPIRUDIN; RECOMBINANT HIRUDIN;

ADULT; ARTICLE; CASE REPORT; CROSS REACTION; DRUG EFFICACY; DRUG SAFETY; FEMALE; HEPARINIZATION; HUMAN; PREGNANCY; PRIORITY JOURNAL; RECURRENT DISEASE; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTOPENIA; VEIN THROMBOSIS;

EID: 0033985671     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000010216     Document Type: Article

References (5)

1. Warkentin TE, Levine MN, Hirsh J, Horsewood P, Gent RRS, Kelton JG: Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995;332: 1330-1135.
2. Greinacher A, Michels I, Kiefel V, Mueller-Eckhardt C: A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia. Thromb Haemost 1991;66:734-736.
3. Greinacher A, Eckhardt T, Mussmann J, Mueller-Eckhardt C: Pregnancy complicated by heparin associated thrombocytopenia: Management by a prospectively in vitro selected heparinoid (Org 101729). Thromb Res 1993; 71:123-126.
4. Markwardt F, Fink G, Kaiser B, Kloecking HP, Nowak G, Richter M, et al: Pharmacological survey of recombinant hirudin. Pharmazie 1988;43:202-207.
5. Eriksson BI, Ekman S, Kaläbo P, Zachrisson B, Bach D, Close P: Prevention of deep-vein thrombosis after total hip replacement: Direct thrombin inhibition with recombinant hirudin, CGP 39393. Lancet 1996;347:635-639.