Differential effects of ethanol on signal transduction

Alcoholism: Clinical and Experimental Research

Volumn 24, Issue 1, 2000, Pages 93-101

  Levine, Gail H ^a   Maglio, Jeff J ^a   Horwitz, Joel ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Chronic Ethanol; MAP Kinase; Neuronal Cells; Phospholipase D; Tyrosine Kinase

Indexed keywords

ALCOHOL; BRADYKININ; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PHOSPHOLIPASE D; PROTEIN TYROSINE KINASE;

ALCOHOL ABUSE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0033985586     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000374-200001000-00014     Document Type: Article

References (61)

1. Allan AM, Harris RA (1987) Acute and chronic ethanol treatments alter GABA receptor-operated chloride channels. Pharmacol Biochem Behav 27:665-670.
2. Aragon CM, Spivak K, Amit Z (1991) Effect of 3-amino-1,2,4-triazole on ethanol-induced narcosis, lethality and hypothermia in rats. Pharm Biochem Behavior 39:55-59.
3. Asaoka Y, Kikkawa U, Sekiguchi K, Shearman MS, Kosaka Y, Nakano Y, Satoh T, Nishizuka Y (1988) Activation of brain-specific protein kinase C subspecies in the presence of phosphatidylethanol. FEBS Lett 231: 221-224.
4. Aspberg A, Soderback M, Tottmar O (1993) Increase in catalase activity in developing rat brain cell reaggregation cultures in the presence of ethanol. Biochem Pharm 46:1873-1876.
5. Charness ME, Querimit LA, Henteleff M (1988) Ethanol differentially regulates G proteins in neural cells. Biochem Biophys Res Commun 155:138-143.
6. Chen J, Ishac EJN, Dent P, Kunos G, Gao B (1998) Effects of ethanol on mitogen-activated protein kinase and stress-activated protein kinase cascades in normal and regenerating liver. Biochem J 334:669-676.
7. Coe IR, Yao L, Diamond I, Gordon AS (1996) The role of protein kinase C in cellular tolerance to ethanol. J Biol Chem 271:29468-29472.
8. Colley WC, Sung T, Roll R, Jenco J, Hammond SM, Altshuller Y, Bar-Sagi D, Morris AJ, Frohman MA (1997) Phospholipase D2, a distinct phospholipaser D isoform with novel regulatory properties that provokes cytoskeletal reorganization. Curr Biol 7:191-201.
9. Davis LL, Maglio JJ, Horwitz J (1998) Phospholipase D hydrolyzes short-chain analogs of phosphatidylcholine in the absence of detergent. Lipids 33:223-227.
10. Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J (1996) A role for Pyk2 and Src in linking G-protein-coupled receptors with Map kinase activation. Nature 383:547-550.
11. Gill K, Menez JF, Lucas D, Deitrich RA (1992) Enzymatic production of acetaldehyde from ethanol in rat brain tissue. Alcohol Clin Exp Res 16:910-915.
12. Gomez-Cambronero J (1995) Immunoprecipitation of a phospholipase D activity with antiphosphotyrosine antibodies J Interferon Cytokine Res 15:877-885.
13. Gordon AS, Collier K, Diamond I (1986) Ethanol regulation of adenosine receptor-stimulated cAMP levels in a clonal neural cell line: An in vitro model of cellular tolerance to ethanol. Proc Natl Acad Sci USA 83: 2105-2108.
14. Greene, LA, Tischler AS (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which responds to nerve growth factor. Proc Natl Acad Sci USA 73:2424-2428.
15. Hammond SM, Altshuller YM, Sung T, Rudge SA, Rose K, Engebrecht J, Morris AJ, Frohman MA (1995) Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family J Biol Chem 270:29640-29643.
16. Hammond SM, Jenco JM, Nakashima S, Cadwallader K, Gu Q, Cook S, Nozawa Y, Prestwich GD, Frohman MA, Morris AJ (1997) Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha. J Biol Chem 272:3860-3868.
17. Hattori H, Kanfer JN (1985) Synaptosomal phospholipase D potential role in providing choline for acetylcholine synthesis. J Neurochem 45:1578-1594.
18. Hoek JB, Thomas AP, Rooney TA, Higashi K, Rubin E (1992) Thanol and signal transduction in the liver. FASEB J 6:2386-2396.
19. Horwitz J (1990) Carbachol and bradykinin increase the production of diacylglycerol from sources other than inositol-containing phospholipids in PC12 cells. J Neurochem 54:983-991.
20. Horwitz J (1991) Bradykinin activates a phospholipase D that hydrolyzes phosphatidylcholine in PC12 cells. J Neurochem 56:509-517.
21. Horwitz J, Davis L (1993) The substrate specificity of brain microsomal phospholipase D. Biochem J 295:793-798.
22. Horwitz J, Perlman RL (1987) Measurement of inositol phospholipid metabolism in PC12 pheochromocytoma cells, in Methods in Enzymology (AR Means, PM Conn eds), vol 141; pp 169-175, Academic Press, Orlando, FL.
23. Houle MG, Bourgoin S (1999) Regulation of phospholipase D by phosphorylation dependent mechanisms. Biochim Biophys Acta 1439:135-149.
24. Imagawa W, Bandyopadhyay GK, Wallace D, Nandi S (1989) Phospholipids containing polyunsaturated fatty acyl groups are mitogenic for normal mouse mammary epithelial cells in serum-free primary culture. Proc Natl Acad Sci USA 86:4122-4126.
25. 2+-dependent protein phosphorylation in carbachol-induced phospholipase D activation in rat pheochromocytoma PC12 cells. J Neurochem 68:419-425.
26. 2+-dependent protein kinase. J Neurochem 69:729-736.
27. 2+ mobilizing stimulus for fibroblasts. Evidence for an extracellular action. J Biol Chem 265: 12232-12239.
28. Kim W-K, Hawthorn M, Rabin R (1993) Differential effects of chronic ethanol exposure on ATP-and bradykinin-induced increases in intracellular calcium levels in PC12 cells. Mol Pharmacol 44:405-411.
29. Kobayashi M, Kanfer JN (1987) Phosphatidylethanol formation via transphosphatidylation by rat brain synaptosomal phospholipase D. J Neurochem 48:1597-1603.
30. Liscovitch M (1989) Phosphatidylethanol biosynthesis in ethanol-exposed NG108-15 neuroblastoma x glioma hybrid cells. J Biol Chem 264:1450-1456.
31. Lovinger DM, White G, Weight FF (1989) Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science (Wash. DC) 243:1721-1724.
32. Lundqvist C, Rodriguez FD, Simonsson P, Alling C, Gustavsson L (1993) Phosphatidylethanol affects inositol 1,4,5-trisphosphate level in NG108-15 neuroblastoma x glioma hybrid cells) J Neurochem 60:738-744.
33. Marcil J, Harbour D, Naccache PH, Bourgoin S (1997) Human phospholipase D1 can be tyrosine-phosphorylated in HL-60 granulocytes. J Biol Chem 272:20660-20664.
34. Messing RO, Carpenter CL, Diamond I, Greenberg DA (1986) Ethanol regulates calcium channels in clonal neural cells. Proc Natl Acad Sci USA 83:6213-6215.
35. Messing RO, Diamond I (1997) Molecular biology of alcohol dependence, in The Molecular and Generic Basis of Neurological Disease (R Rosenberg, S Prusiner, S DiMauro, and R Barchi eds), p. 1109-1126. Butterworth-Heinemann, Boston.
36. Messing RO, Peterson PJ, Henrich CJ (1991) Chronic ethanol exposure increases levels of protein kinase C and protein kinase C-mediated phosphorylation in cultured neural cells. J Biol Chem 266:23428-23432.
37. Min DS, Kim E-G, Exton JH (1998) Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in swiss 3T3 fibroblasts. J Biol Chem 273:29986-29994.
38. Montoliu C, Valles S, Renau-Piqueras J, Guerri C (1994) Ethanol-induced oxygen radical formation and lipid peroxidation in rat brain: Effect of chronic alcohol consumption. J Neurochem 63:1855-1862.
39. Moolenaar WH, Kruijer W, Tilly BC, Verlaan I, Bierman AJ, de Laat SW (1986) Growth factor-like action of phosphatidic acid. Nature 323:171-173.
40. - uptake in cerebral cortical synaptoneurosomes. J Pharmacol Exp Ther 246:158-164.
41. Nagy LE (1996) Alcohol and tyrosine kinase/phosphatase mediated processes. Alcohol Clin Exp Res 20:106A-108A.
42. 2-induced activation of endothelial cell phospholipase D. Am J Physio L:400-408.
43. Omodeo-Sale F, Lindi C, Palestini P, Masserini M (1991) Role of phosphatidylethanol in membranes. Effects on membrane fluidity, tolerance to ethanol, and activity of membrane bound enzymes. Biochemistry 30:2477-2482.
44. Pantazis NJ, Dohrman DP, Luo J, Goodlett CR, West JR (1992) Alcohol reduces the number of pheochromocytoma (PC12) cells in culture. Alcohol 9:171-180.
45. Patel BC, D'Arville C, Iwahashi M, Simon FR (1991) Impairment of hepatic insulin receptors during chronic ethanol administration. Am J Physiol 261:G199-G205.
46. Peoples RW, Li C, Weight FF (1996) Lipid vs protein theories of alcohol action in the nervous system. Annu Rev Pharmacol Toxicol 36:185-201.
47. Pittman RN, Wang S, DiBenedetto AJ, Mills JC (1993) A system for characterizing cellular and molecular events in programmed neuronal cell death. J Neurosci 13:3669-3380.
48. Pittner RA, Fain JN (1992) Ethanol is potent stimulator of phosphatidylcholine breakdown in cultured rat hepatocytes. Biochim Biophys Acta 1133:316-320.
49. Reddy MA, Shukla SD (1996) Potentiation of mitogen-activated protein kinase by ethanol in embryonic liver cells. Biochem Pharm 51:661-668.
50. Resnicoff M, Rubin M, Baserga, R, Rubin R (1994) Ethanol inhibits insulin-like growth factor-1-mediated signaling and proliferation of C6 rat glioblastoma cells. Lab Invest 71:657-662.
51. Rodriguez FD, Simonsson P, Gustavsson L, Alling C (1992) Mechanism of adaptation to the effects of ethanol on phospholipase C activation in NG 108-15 cells. Neuropharmacology 31:1157-1164.
52. Roivainen R, Hundle B, Messing RO (1994) Protein kinase C and adaptation to ethanol. EXS 71:29-38.
53. Roivainen R, Hundle B, Messing RO (1995) Ethanol enhances growth factor activation of MAP kinases by a protein kinase C-dependent mechanism. Proc Natl Acad Sci USA 92:1891-1895.
54. Simonsson P, Sun GY, Vecsei L, Alling C (1989) Ethanol effects on bradykinin-stimulated phosphoinositide hydrolysis in NG 108-15 neuroblastoma x glioma hybrid cells. Alcohol 6:475-479.
55. 2+ uptake in synaptosomes and in PC12 cells. Biochem Pharmacol 36:2227-2229.
56. Snell LD, Tabakoff B, Hoffman PL (1993) Radioligand binding to the N-methyl-D-aspartate receptor/ionophore complex: Alterations by ethanol in vitro and by chronic in vivo ethanol ingestion. Brain Res 602:91-98.
57. Sun GY, Navidi M, Yoa FG, Lin T (1991) Effects of acute and chronic ethanol administration on phosphoinositide metabolism in mouse brain. Alcohol Alcohol Suppl 1:215-219.
58. Traynor AE, Schubert D, Allen WR (1982) Alterations of lipid metabolism in response to nerve growth factor. J Neurochem 39:1677-1683.
59. Tuma DJ, Todero SL, Barak-Bernhagen M, Casey CA (1998) Chronic ethanol ingestion impairs TGF-alpha-stimulated receptor autophosphorylation. Alcohol 15:233-238.
60. Wand GS, Diehl AM, Levine MA, Wolfgang D, Samy S (1993) Chronic ethanol treatment increases expression of inhibitory G-proteins and reduces adenylylcyclase activity in the central nervous system of two lines of ethanol-sensitive mice. J Biol Chem 268:2595-2601.
61. Zwick E, Daub H, Aoki N, Yamaguchi-Aoki Y, Tinhofer I, Maly K, Ullrich A (1997) Critical role of calcium-dependent epidermal growth factor transactivation in PC12 cell membrane depolarization and bradykinin signaling. J Biol Chem 272:24767-24770.