-
1
-
-
0032514918
-
BAD enables ceramide to signal apoptosis via Ras and Raf-1
-
Basu S, Bayoumy S, Zhang Y, Lozano S, Kolesnick RJ. 1998. BAD enables ceramide to signal apoptosis via Ras and Raf-1, J Biol Chem 273:30419-30426.
-
(1998)
J Biol Chem
, vol.273
, pp. 30419-30426
-
-
Basu, S.1
Bayoumy, S.2
Zhang, Y.3
Lozano, S.4
Kolesnick, R.J.5
-
2
-
-
0021443856
-
Inositol triphosphate and diacylglycerol as second messenger
-
Berridge MJ. 1986. Inositol triphosphate and diacylglycerol as second messenger. Biochem J 220:345-360.
-
(1986)
Biochem J
, vol.220
, pp. 345-360
-
-
Berridge, M.J.1
-
3
-
-
0022270868
-
5]enkephalin-induced supersensitivity to 5-hydroxytryptamine in a neurotumor X brain hybrid cell line (NCB-20)
-
5]enkephalin-induced supersensitivity to 5-hydroxytryptamine in a neurotumor X brain hybrid cell line (NCB-20). J Neurochem 45:1731-1738.
-
(1985)
J Neurochem
, vol.45
, pp. 1731-1738
-
-
Berry-Kravis, E.1
Dawson, G.2
-
4
-
-
0032500730
-
Bifurcation of lipid and protein kinase signals of PI3Kγ to the protein kinases PKB and MAPK
-
Bondeva T, Pirola L, Bulgarelli-Leva G, Rubio I, Wetzker R, Wymann MP. 1998. Bifurcation of lipid and protein kinase signals of PI3Kγ to the protein kinases PKB and MAPK Science 282: 293-296.
-
(1998)
Science
, vol.282
, pp. 293-296
-
-
Bondeva, T.1
Pirola, L.2
Bulgarelli-Leva, G.3
Rubio, I.4
Wetzker, R.5
Wymann, M.P.6
-
5
-
-
0023837788
-
Effects of opioid compounds on basal and muscarinic induced accumulation of inositol phosphates in cultured bovine chromaffin cells
-
Bunn SJ, Marley PD, Livett BG. 1988. Effects of opioid compounds on basal and muscarinic induced accumulation of inositol phosphates in cultured bovine chromaffin cells. Biochem Pharmacol 37:395-399.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 395-399
-
-
Bunn, S.J.1
Marley, P.D.2
Livett, B.G.3
-
6
-
-
0029055483
-
2+ increase by bradykinin or ATP in NG108-15 cells
-
2+ increase by bradykinin or ATP in NG108-15 cells. J Biol Chem 270:16630-16637.
-
(1995)
J Biol Chem
, vol.270
, pp. 16630-16637
-
-
Chueh, S.H.1
Song, S.L.2
Liu, T.Y.3
-
7
-
-
0032189381
-
Protein kinase B (c-Akt): A multi-functional mediator of phosphatidylinositol 3-kinase activation
-
Coffer PJ, Jin J, Woodgett JR. 1998. Protein kinase B (c-Akt): a multi-functional mediator of phosphatidylinositol 3-kinase activation Biochem J 335:1-13.
-
(1998)
Biochem J
, vol.335
, pp. 1-13
-
-
Coffer, P.J.1
Jin, J.2
Woodgett, J.R.3
-
8
-
-
0029957393
-
Modulatory effects of Gs-coupled excitatory opioid receptor functions on opioid analgesia, tolerance, and dependence
-
Crain SM, Shen KF. 1996. Modulatory effects of Gs-coupled excitatory opioid receptor functions on opioid analgesia, tolerance, and dependence. Neurochem Res 21:1347-1351.
-
(1996)
Neurochem Res
, vol.21
, pp. 1347-1351
-
-
Crain, S.M.1
Shen, K.F.2
-
9
-
-
0028973270
-
Dual effect of β-adrenergic receptors on mitogen-activated protein kinase
-
Crespo P, Cachero TG, Xu N, Gutkind JS. 1995. Dual effect of β-adrenergic receptors on mitogen-activated protein kinase. J Biol Chem 270:25259-25265.
-
(1995)
J Biol Chem
, vol.270
, pp. 25259-25265
-
-
Crespo, P.1
Cachero, T.G.2
Xu, N.3
Gutkind, J.S.4
-
10
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91: 231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
11
-
-
0030983782
-
Chronic exposure to kappa opioids enhances the susceptibility of immortalized neurons (F-11k7) to apoptosis-inducing drugs by a mechanism that involves ceramide
-
Dawson G, Dawson SA, Goswami R. 1997. Chronic exposure to kappa opioids enhances the susceptibility of immortalized neurons (F-11k7) to apoptosis-inducing drugs by a mechanism that involves ceramide. J Neurochem 68:2363-2370.
-
(1997)
J Neurochem
, vol.68
, pp. 2363-2370
-
-
Dawson, G.1
Dawson, S.A.2
Goswami, R.3
-
12
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase akt
-
del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. 1997. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687-689.
-
(1997)
Science
, vol.278
, pp. 687-689
-
-
Peso, L.1
Gonzalez-Garcia, M.2
Page, C.3
Herrera, R.4
Nunez, G.5
-
13
-
-
0030786202
-
Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin
-
Duckworth BC, Cantley LC. 1997. Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. J Biol Chem 272:27665-27670.
-
(1997)
J Biol Chem
, vol.272
, pp. 27665-27670
-
-
Duckworth, B.C.1
Cantley, L.C.2
-
14
-
-
0022525480
-
Bradykinin induces a rapid release of inositol triphosphate from a neuroblastoma hybrid cell line NCB-20 that is not antagonized by enkephalin
-
Francel P, Dawson G. 1986. Bradykinin induces a rapid release of inositol triphosphate from a neuroblastoma hybrid cell line NCB-20 that is not antagonized by enkephalin. Biochem Biophys Res Commun 135:507-514.
-
(1986)
Biochem Biophys Res Commun
, vol.135
, pp. 507-514
-
-
Francel, P.1
Dawson, G.2
-
15
-
-
0023196344
-
Neurochemical characteristics of a novel dorsal root ganglion neuroblastoma hybrid cell line, F-11
-
Francel PC, Harris K, Smith M, Fishman MC, Dawson G, Miller RJ. 1987a. Neurochemical characteristics of a novel dorsal root ganglion neuroblastoma hybrid cell line, F-11. J Neurochem 48:1624-1631.
-
(1987)
J Neurochem
, vol.48
, pp. 1624-1631
-
-
Francel, P.C.1
Harris, K.2
Smith, M.3
Fishman, M.C.4
Dawson, G.5
Miller, R.J.6
-
16
-
-
0023197189
-
Modulation of bradykinin-induced inositol triphosphate release in a novel neuroblastoma X dorsal root ganglion sensory neuron cell line (F-11)
-
Francel PC, Miller RJ, Dawson G. 1987b. Modulation of bradykinin-induced inositol triphosphate release in a novel neuroblastoma X dorsal root ganglion sensory neuron cell line (F-11). J Neurochem 48:1632-1639.
-
(1987)
J Neurochem
, vol.48
, pp. 1632-1639
-
-
Francel, P.C.1
Miller, R.J.2
Dawson, G.3
-
17
-
-
0031566693
-
A Bad kinase makes good
-
Franke TF, Cantley LC. 1997. A Bad kinase makes good. Nature 390:116-117.
-
(1997)
Nature
, vol.390
, pp. 116-117
-
-
Franke, T.F.1
Cantley, L.C.2
-
19
-
-
0031882017
-
Cyclic AMP protects against staurosporine and wortmannin-induced apoptosis and opioid-enhanced apoptosis in both embryonic and immortalized (F-11K7) neurons
-
Goswami R, Dawson SA, Dawson G. 1998. Cyclic AMP protects against staurosporine and wortmannin-induced apoptosis and opioid-enhanced apoptosis in both embryonic and immortalized (F-11K7) neurons. J Neurochem 70:1376-1382.
-
(1998)
J Neurochem
, vol.70
, pp. 1376-1382
-
-
Goswami, R.1
Dawson, S.A.2
Dawson, G.3
-
20
-
-
0032404536
-
The central executioners of apoptosis: Caspases or mitochondria?
-
Green D, Kroemer G. 1998. The central executioners of apoptosis: caspases or mitochondria? Trends Cell Biol 8:267-271.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 267-271
-
-
Green, D.1
Kroemer, G.2
-
21
-
-
0024595042
-
Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
-
Hansen M, Nielsen S, Berg K. 1989. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 119:203-210.
-
(1989)
J Immunol Methods
, vol.119
, pp. 203-210
-
-
Hansen, M.1
Nielsen, S.2
Berg, K.3
-
22
-
-
0028782769
-
The ins and outs of programmed cell death during C. elegans development
-
Hengartner MO, Horvitz HR. 1994. The ins and outs of programmed cell death during C. elegans development. Philos Trans R Soc Lond B Biol Sci 345:243-246.
-
(1994)
Philos Trans R Soc Lond B Biol Sci
, vol.345
, pp. 243-246
-
-
Hengartner, M.O.1
Horvitz, H.R.2
-
23
-
-
0027087472
-
Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma X glioma hybrid NG108-15 cells
-
Jin W, Lee NM, Loh HH, Thayer SA. 1992. Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma X glioma hybrid NG108-15 cells. Molec Pharmacol 42: 1083-1089.
-
(1992)
Molec Pharmacol
, vol.42
, pp. 1083-1089
-
-
Jin, W.1
Lee, N.M.2
Loh, H.H.3
Thayer, S.A.4
-
24
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
-
Kennedy SG, Wagner AJ, Conzen SD, Jordan J, Bellacosa A, Tsichlis PN, Hay N. 1997. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev 11:701-713.
-
(1997)
Genes Dev
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
Wagner, A.J.2
Conzen, S.D.3
Jordan, J.4
Bellacosa, A.5
Tsichlis, P.N.6
Hay, N.7
-
25
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
-
Kuida K, Haydar TF, Kuan C, Gu Y, Taya C, Karasuyama H, Su M S-S, Rakic P, Flavell RA. 1998. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 94:325-337.
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.3
Gu, Y.4
Taya, C.5
Karasuyama, H.6
Su, M.S.-S.7
Rakic, P.8
Flavell, R.A.9
-
26
-
-
0027403710
-
μ and δ-opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells
-
Laugwitz K-L, Offermanns S, Spicher K, Schultz G. 1993. μ and δ-opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells. Neuron 10:233-242.
-
(1993)
Neuron
, vol.10
, pp. 233-242
-
-
Laugwitz, K.-L.1
Offermanns, S.2
Spicher, K.3
Schultz, G.4
-
27
-
-
0032431028
-
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells
-
Li DM, Sun H. 1998. PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. Proc Natl Acad Sci USA 95:15406-15411.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15406-15411
-
-
Li, D.M.1
Sun, H.2
-
28
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon J. 1998. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273:13375-13378.
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.2
-
29
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers MP, Stolarov JP, Eng C, Li J, Wang SI, Wigler MH, Parsons R, Tonks NK. 1997. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci USA 94:9052-9057.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, N.K.8
-
30
-
-
0027499863
-
2+ system through cross-talk between opioid receptors and p2-purinergic or bradykinin receptors in NG108-15 cells
-
2+ system through cross-talk between opioid receptors and p2-purinergic or bradykinin receptors in NG108-15 cells. Biochem J 290:241-247.
-
(1993)
Biochem J
, vol.290
, pp. 241-247
-
-
Okajima, F.1
Tomura, H.2
Kondo, Y.3
-
31
-
-
0028006303
-
Pharmacological characterization of the cloned K-, δ-, and μ-opioid receptors
-
Raynor K, Kong H, Chen Y, Yasuda K, Yu L, Bell G, Reisine T. 1993. Pharmacological characterization of the cloned K-, δ-, and μ-opioid receptors. Mol Pharmacol 45:330-334.
-
(1993)
Mol Pharmacol
, vol.45
, pp. 330-334
-
-
Raynor, K.1
Kong, H.2
Chen, Y.3
Yasuda, K.4
Yu, L.5
Bell, G.6
Reisine, T.7
-
32
-
-
0032560514
-
Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/Akt: Involvement of MEK upstream of Bad phosphorylation
-
Scheid M, Duronio V. 1998. Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/Akt: involvement of MEK upstream of Bad phosphorylation. Proc Natl Acad Sci USA 95 :7439-7444.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7439-7444
-
-
Scheid, M.1
Duronio, V.2
-
33
-
-
0028181464
-
Mu-opioid receptor stimulation of (1,4,5)-triphosphate formation via a pertussis toxin-sensitive G protein
-
Smart D, Smith G, Lambert DG. 1994a. Mu-opioid receptor stimulation of (1,4,5)-triphosphate formation via a pertussis toxin-sensitive G protein. J Neurochem 62:1009-1014.
-
(1994)
J Neurochem
, vol.62
, pp. 1009-1014
-
-
Smart, D.1
Smith, G.2
Lambert, D.G.3
-
34
-
-
0028329417
-
Halothane and isoflurane enhance basal and carbachol-stimulated inositol (1,4,5)-triphosphate formation in SH-SY5Y human neuroblastoma cells
-
Smart D, Smith G, Lambert DG. 1994b. Halothane and isoflurane enhance basal and carbachol-stimulated inositol (1,4,5)-triphosphate formation in SH-SY5Y human neuroblastoma cells. Biochem Pharmacol 47:939-945.
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 939-945
-
-
Smart, D.1
Smith, G.2
Lambert, D.G.3
-
35
-
-
0028979661
-
Mu-opioids activate phospholipase C in SH-SY5Y human neuroblastoma cells via calcium-channel opening
-
Smart D, Smith G, Lambert DG. 1995. Mu-opioids activate phospholipase C in SH-SY5Y human neuroblastoma cells via calcium-channel opening. Biochem J 305:577-582.
-
(1995)
Biochem J
, vol.305
, pp. 577-582
-
-
Smart, D.1
Smith, G.2
Lambert, D.G.3
-
36
-
-
0031812221
-
Contribution of phospholipase C-b3 phosphorylation to the rapid attenuation of opioid-activated phosphoinositide response
-
Strassheim D, Law P-Y, Loh HH. 1999. Contribution of phospholipase C-b3 phosphorylation to the rapid attenuation of opioid-activated phosphoinositide response. Molec Pharmacol 53:1047-1053.
-
(1999)
Molec Pharmacol
, vol.53
, pp. 1047-1053
-
-
Strassheim, D.1
Law, P.-Y.2
Loh, H.H.3
-
37
-
-
13044305289
-
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/ protein kinase B signaling pathway
-
Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J, Gavrilova N, Mueller B, Liu X, Wu H. 1999. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/ protein kinase B signaling pathway. Proc Natl Acad Sci USA 96:6199-6204.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6199-6204
-
-
Sun, H.1
Lesche, R.2
Li, D.M.3
Liliental, J.4
Zhang, H.5
Gao, J.6
Gavrilova, N.7
Mueller, B.8
Liu, X.9
Wu, H.10
-
38
-
-
0342720387
-
Regulation of N-type calcium channels by opioid receptors in a sensory neuronal cell line
-
Toth P, Dawson G, Goswami R, Jastrow A, Miller RJ. 1996. Regulation of N-type calcium channels by opioid receptors in a sensory neuronal cell line. J Neurosci 21:514.
-
(1996)
J Neurosci
, vol.21
, pp. 514
-
-
Toth, P.1
Dawson, G.2
Goswami, R.3
Jastrow, A.4
Miller, R.J.5
-
39
-
-
0347537940
-
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
-
Verheij M, Bose R, Lin X H, Yao B, Jarvis WD, Grant S, Birrer MJ, Szabo E, Zon LI, Dyriakis J M, Halmovity-Friedman A, Fuks Z, Kolesnick RN. 1996. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 380:75-79.
-
(1996)
Nature
, vol.380
, pp. 75-79
-
-
Verheij, M.1
Bose, R.2
Lin, X.H.3
Yao, B.4
Jarvis, W.D.5
Grant, S.6
Birrer, M.J.7
Szabo, E.8
Zon, L.I.9
Dyriakis, J.M.10
Halmovity-Friedman, A.11
Fuks, Z.12
Kolesnick, R.N.13
-
40
-
-
0033081893
-
Atypical PKC zeta is activated by ceramide, resulting in coactivation of NF-kappaB/JNK kinase and cell survival
-
Wang YM, Seibenhener ML, Vandenplas ML, Wooten MW. 1999 Atypical PKC zeta is activated by ceramide, resulting in coactivation of NF-kappaB/JNK kinase and cell survival. J Neurosci Res 55:293-302.
-
(1999)
J Neurosci Res
, vol.55
, pp. 293-302
-
-
Wang, Y.M.1
Seibenhener, M.L.2
Vandenplas, M.L.3
Wooten, M.W.4
-
41
-
-
0029987190
-
Staurosporine induces programmed cell death in embryonic neurons and activation of the ceramide pathway
-
Wiesner DA, Dawson G. 1996a. Staurosporine induces programmed cell death in embryonic neurons and activation of the ceramide pathway. J Neurochem 66:1418-1425.
-
(1996)
J Neurochem
, vol.66
, pp. 1418-1425
-
-
Wiesner, D.A.1
Dawson, G.2
-
42
-
-
0029981990
-
Programmed cell death in neurotumor cells involves the generation of ceramide
-
Wiesner DA, Dawson G. 1996b. Programmed cell death in neurotumor cells involves the generation of ceramide. Glycoconjugate J 13:327-333.
-
(1996)
Glycoconjugate J
, vol.13
, pp. 327-333
-
-
Wiesner, D.A.1
Dawson, G.2
-
43
-
-
0030950234
-
Anti-immunoglobulin-induced apoptosis in WEHI-231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-xL
-
Wiesner DA, Kilkus JP, Gottschalk AR, Quintans J, Dawson G. 1997. Anti-immunoglobulin-induced apoptosis in WEHI-231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-xL. J Biol Chem 272:9868-9876.
-
(1997)
J Biol Chem
, vol.272
, pp. 9868-9876
-
-
Wiesner, D.A.1
Kilkus, J.P.2
Gottschalk, A.R.3
Quintans, J.4
Dawson, G.5
-
44
-
-
0029906828
-
Bax-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases
-
Xiang L, Chao DT, Korsmeyer SJ. 1996. Bax-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc Natl Acad Sci USA 93:14559-14563.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14559-14563
-
-
Xiang, L.1
Chao, D.T.2
Korsmeyer, S.J.3
-
46
-
-
0343742670
-
Kinase suppressor of Ras is ceramide-activated protein kinase
-
Zhang Y, Yao B, Delikat S, Bayoumy S, Lin XH, Basu S, McGinley M, Chan-Hui PY, Lichenstein H, Kolesnick R. 1997. Kinase suppressor of Ras is ceramide-activated protein kinase. Cell 89:63-72.
-
(1997)
Cell
, vol.89
, pp. 63-72
-
-
Zhang, Y.1
Yao, B.2
Delikat, S.3
Bayoumy, S.4
Lin, X.H.5
Basu, S.6
McGinley, M.7
Chan-Hui, P.Y.8
Lichenstein, H.9
Kolesnick, R.10
-
47
-
-
0032569026
-
Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis
-
Zhou H, Summers S A, Birnbaum MJ, Pittman R. 1998. Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis. J Biol Chem 273:16568-16575.
-
(1998)
J Biol Chem
, vol.273
, pp. 16568-16575
-
-
Zhou, H.1
Summers, S.A.2
Birnbaum, M.J.3
Pittman, R.4
-
48
-
-
0032128301
-
Inhibition of the anti-apoptotic PI(3)K/Akt/ Bad pathway by stress
-
Zundel W, Giaccia A. 1998. Inhibition of the anti-apoptotic PI(3)K/Akt/ Bad pathway by stress. Genes Dev 12:1941-1946.
-
(1998)
Genes Dev
, vol.12
, pp. 1941-1946
-
-
Zundel, W.1
Giaccia, A.2
|