Chemoselective reduction of aldehydes in the presence of ketones utilizing Raney nickel

Synlett

Volumn , Issue 2, 2000, Pages 197-200

  Barrero, Alejandro F ^a   Alvarez Manzaneda, E J ^a   Chahboun, Rachid ^a   Meneses, R ^a  

^a UNIVERSITY OF GRANADA   (Spain)

Author keywords

Aldehydes; Chemoselectivity; Ketones; Reduction

Indexed keywords

ALDEHYDE; KETONE; NICKEL;

ANALYTIC METHOD; ARTICLE; CATALYSIS; DRUG SYNTHESIS; HYDROGENATION; MOLECULAR RECOGNITION; QUANTITATIVE TRAIT; REACTION ANALYSIS;

EID: 0033984516     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-6498     Document Type: Article

References (15)

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14. 3) δ: 0.88 (s, 3H), 0.96 (s, 3H), 2.10 (br d, J = 13.4 Hz, 1H), 2.22 (dd, J = 11.9 and 2.5 Hz, 1H), 2.34 (br s, 1H), 9.70 (d, J = 1.2 Hz, 1H).
15. Typical experimental procedure: 0.8 g of an aqueous suspension of Raney nickel (Fluka, cat. no. 83440) was added to a stirred solution of compound (1.0 mmol) in tetrahydrofuran (10 ml) and the mixture was further stirred at room temperature for the specified time (Table). The mixture was diluted with ether and Filtered through celite, and the solvent was evaporated to yield the reduced compound.