Primary respiratory syncytial virus infection: Pathology, immune response, and evaluation of vaccine challenge strains in a new mouse model

Vaccine

Volumn 18, Issue 14, 2000, Pages 1412-1418

  Stack, Anne M ^a   Malley, Richard ^a,b   Saladino, Richard A ^a   Montana, John B ^b   MacDonald, Kristin L ^b   Molrine, Deborah C ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Animal model; Respiratory syncytial virus; Vaccine

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 5; RESPIRATORY SYNCYTIAL VIRUS VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; IMMUNE RESPONSE; LUNG INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VACCINATION; VACCINE PRODUCTION; VIRUS PATHOGENESIS;

ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; MICE; MICE, INBRED BALB C; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; VIRAL VACCINES;

EID: 0033984194     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(99)00399-0     Document Type: Article

References (24)

1. Anonymous. Update: respiratory syncytial virus activity - United States, 1997-98 season. MMWR - Morbidity & Mortality Weekly Report. 46:1997;1163-1165.
2. Glezen W., Denny F.W. Epidemiology of acute lower respiratory disease in children. New England Journal of Medicine. 288:1973;498-505.
3. Hall C.B. Prospects for a respiratory syncytial virus vaccine. Science. 265:1994;1393-1394.
4. Berkovich S. Acute respiratory illness in the premature nursery associated with respiratory syncytial virus infections. Pediatrics. 34:1964;753-760.
5. MacDonald N.E. H.C., Suffin S.C., Alexson C., Harris P.J., Manning J.A. Respiratory syncytial virus infection in infants with congenital heart disease. New England Journal of Medicine. 307:1982;397-400.
6. Groothius J., Gutierrez K.M., Lauer B.A. Respiratory syncytial virus infection in children with bronchopulmonary dysplasia. Pediatrics. 82:1988;199-203.
7. Falsey A.R. T.J., Betts R.F., Walsh E.E. Viral respiratory infections in the institutionalized elderly: clinical and epidemiologic findings. JAGS. 40:1992;115-119.
8. Fouillard L.L. M.L., Laporte J.P., Isnard F., Stachowiak J., Aoudjhane M., Lucet J.C., Wolf M., Bricourt F., Douay L., Marche C., Nakman A., Gorin N.C. Severe respiratory syncytial virus pneumonia after autologous bone marrow translpant: a report of three cases and a review. Bone Marrow Transplantation. 9:1992;97-100.
9. Rooney J.C., Williams H.E. The relationship between proved viral bronchiolitis and subsequent wheezing. Journal of Pediatrics. 79:1971;744-747.
10. Gurwitz D. M.C., Levison H. Increased incidence of bronchial reactivity in children with a history of bronchiolitis. Journal of Pediatrics. 98:1981;551-555.
11. Twiggs J.T., Larson L.A., O'Connell E.J., Ilstrup D.M. Respiratory syncytial virus infection: ten-year follow-up. Clin Pediatr (Phila). 20:1981;187-190.
12. Schwarze J., Hamelmann E., Bradley K.L., Takeda K., Gelfand E.W. Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen. J. Clin. Invest. 100:1997;226-233.
13. Graham B.S., Perkins M.D., Wright P.F., Karzon D.T. Primary respiratory syncytial virus infection in mice. J. Med. Virol. 26:1988;153-162.
14. Malley R., DeVincenzo J., Ramilo O., et al. Reduction of respiratory syncytial virus (RSV) in tracheal aspirates in intubated infants by use of humanized monoclonal antibody to RSV F protein. J. Infect. Dis. 178:1998;1555-1561.
15. Murphy B.R., Sotnikov A., Paradiso P.R., et al. Immunization of cotton rats with the fusion (F) and large (G) glycoproteins of respiratory syncytial virus (RSV) protects against RSV challenge without potentiating RSV disease. Vaccine. 7:1989;533-540.
16. Platzer C., Richter G., Uberla K., et al. Analysis of cytokine mRNA levels in interleukin-4-transgenic mice by quantitative polymerase chain reaction. Eur. J. Immunol. 22:1992;1179-1184.
17. Malley R. M.J., Huntoon S.A., Thompson C., Ambrosino D.A., Kurt-Jones E. Quantitative reverse transcriptase polymerase chain reaction (RT-PCR) assessment of T helper cell response in a murine model of respiratory syncytial virus (RSV) infection. Pediatric Research. 41:126A:(abstract):1997.
18. Prince G.A., Horswood R.L., Camargo E., Koenig D., Chanock R.M. Mechanisms of immunity to respiratory syncytial virus in cotton rats. Infect. Immun. 42:1983;81-87.
19. Bangham C.R., Cannon M.J., Karzon D.T., Askonas B.A. Cytotoxic T-cell response to respiratory syncytial virus in mice. J. Virol. 56:1985;55-59.
20. Cannon M.J., Stott E.J., Taylor G., Askonas B.A. Clearance of persistent respiratory syncytial virus infections in immunodeficient mice following transfer of primed T cells. Immunology. 62:1987;133-138.
21. Graham B.S., Henderson G.S., Tang Y.W., Lu X., Neuzil K.M., Colley D.G. Priming immunization determines T helper cytokine mRNA expression patterns in lungs of mice challenged with respiratory syncytial virus. J. Immunol. 151:1993;2032-2040.
22. Connors M., Giese N.A., Kulkarni A.B., Firestone C.Y., Morse 3rd H.C., Murphy B.R. Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10. J. Virol. 68:1994;5321-5325.
23. Anderson L.J., Tsou C., Potter C., et al. Cytokine response to respiratory syncytial virus stimulation of human peripheral blood mononuclear cells. J. Infect. Dis. 170:1994;1201-1208.
24. Schwarze J., Cieslewicz G., Hamelmann E., et al. IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection. J. Immunol. 162:1999;2997-3004.