High-level expression of chromosomally encoded SHV-1 β-lactamase and an outer membrane protein change confer resistance to ceftazidime and piperacillin-tazobactam in a clinical isolate of Klebsiella pneumoniae

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 2, 2000, Pages 362-367

  Rice, Louis B ^a,b   Carias, Lenore L ^a   Hujer, Andrea M ^a   Bonafede, Mary ^a   Hutton, Rebecca ^a   Hoyen, Claudia ^a   Bonomo, Robert A ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; BETA LACTAMASE; CEFOXITIN; CEFTAZIDIME; OUTER MEMBRANE PROTEIN; PIPERACILLIN PLUS TAZOBACTAM;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENETIC RESISTANCE; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PENICILLIN RESISTANCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRAIN DIFFERENCE;

BACTERIAL OUTER MEMBRANE PROTEINS; BASE SEQUENCE; BETA-LACTAMASES; BIOLOGICAL TRANSPORT; CEFTAZIDIME; CEPHALOSPORINS; CHROMOSOMES; CLONING, MOLECULAR; DNA, BACTERIAL; DRUG RESISTANCE, MICROBIAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID HYBRIDIZATION; PENICILLANIC ACID; PENICILLINS; PIPERACILLIN; PROMOTER REGIONS (GENETICS); SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0033984076     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.2.362-367.2000     Document Type: Article

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