Clonal diversity of Ig and T-cell receptor gene rearrangements in childhood B-precursor acute lymphoblastic leukaemia

Leukemia and Lymphoma

Volumn 36, Issue 3-4, 2000, Pages 213-224

  Stankovic, Tatjana ^a   Weston, Victoria ^a,d   McConville, Carmel M ^b   Green, Elaine ^b   Powell, Judith E ^c   Mann, Jillian R ^d   Darbyshire, Philip J ^d   Taylor, A Malcolm R ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b Division of Medical Genetics   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

B precursor ALL; Clonal diversity; Immune system gene rearrangements

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; T LYMPHOCYTE RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALLELE; ARTICLE; CHILDHOOD LEUKEMIA; DISEASE COURSE; GENE REARRANGEMENT; GENETIC RECOMBINATION; HEMATOPOIETIC CELL; HEREDITY; HUMAN; MOLECULAR GENETICS; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR GENE; RELAPSE;

EID: 0033983130     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009148843     Document Type: Article

References (55)

1. Dow, L.W., Martin, P., Moohr, J., Greenberg, M., Macdougall, L.G., Najfield, V. and Fialkow, P.J. (1985). Evidence for clonal development of childhood lymphoblastic leukaemia. Blood, 66, 902-907.
2. Rinaldi, F. Mairs, R.J., Wheldon, T.E., Katz, F., Chessells, J.M. and Gibson, B.E. (1999). Clonality suggests that early-onset acute lymphoblastic leukaemia is of single-cell origin and implies no major role for germ cell mutations in parents. Br J Cancer, 80, 909-913.
3. Yunis, J.J. (1983) The chromosomal basis of human neoplasia. Science, 221, 227-236.
4. Mayumi, M., Jubagawa, H., Omura, G.A., Gathungs, W.E., Kearney, J.F. and Cooper, M.D. (1982). Studies on the clonal origin of human B-cell leukaemia using monoclonal anti-idiotype antibodies. J Immunol, 129, 904-910.
5. H gene rearrangements. Blood, 87, 2506-2512.
6. Fey, M.F., Tobler, A., Stadelman, B., Hirt, A., Theilkas, L., Khandijan, E.W., Ridolfi-Luthy, A., Delaleu, B., Weil, R. and Wagner, H.P. (1990). Immunophenotyping with antigen receptor gene probes as a diagnostic tool in childhood lymphoblastic leukaemia. Eur J Haematol, 75, 1834-1840.
7. Arnold, A., Cossman, J., Bakhshi, A., Jaffe, E., Waldman, T.A. and Korsmeyer, S. (1983). Immunoglobulin gene rearangements as unique clonal marker in human lymphoid neoplasms. N Engl J Med, 309, 1593-1599.
8. Trainor, K.J., Brisco, M.J., Wan, J.H., Neoh, S., Grist, S. and Morley A.A. (1991). Gene rearrangement in B and T lymphoproliferative disease detected by the polymerase chain reaction. Blood, 78, 192-196.
9. Potter, M.N., Steward, C.G., Maitland, N.J. and Oakhill, A. (1992). Detection of clonality in childhood B-lineage acute lymphoblastic leukaemia by the polymerase chain reaction. Leukemia, 6, 289-294.
10. Deane, M. and Norton, J.D. (1991). Preferential rearrangement of developmentally regulated immunoglobulin VH1 genes in human B-lineage leukaemias. Leukemia, 5, 646-650.
11. Felix, C.A., Poplack, D.G., Reaman, G.H., Steinberg, S.M., Cole, D. E., Taylor, B.J., Begley, C.G. and Kirsch, I.R. (1990). Characterization of immunoglobulin and T-cell receptor gene patterns in B-cell precursor acute lymphoblastic leukemia of childhood. J Clin Oncol, 8, 431-442.
12. Hara, J., Benedict, S.H., Champagne, E., Takihara, Y., Mak, T.W., Minden, M. and Gelfand, E.W. (1988). T cell receptor delta rearrangements in B-precursor acute lymphoblastic leukaemia correlate with age and the stage of B cell differentiation. Leukaemia, 2, 722-727.
13. Stankovic, T., Mann, J.R., Darbyshire, P.J. and Taylor, A.M.R. (1995). Clonal diversity, measured by heterogeneity of Ig and TCR gene rearrangements, in some acute leukaemias of childhood is associated with a more aggressive disease. Eur J Cancer, 31A, 394-401.
14. Beishuizen, A., Verhoeven, MA. J., Vanwering, E.R., Hahlen, K., Hooijkaas, H. and Vandongen, J.J.M. (1994). Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: Implication for the detection of minimal residual disease by polymerase chain reaction analysis. Blood, 83, 2238-2247.
15. Dyer, M.J. (1989). T-cell receptor delta/alpha rearrangements in lymphoid neoplasms Blood, 74, 1073-1083.
16. Forestier, E., Nordenson, I., Lindstrom A., Roos, G. and Lindh, J. (1994). Simultaneous immunoglobulin/T cell receptor gene rarrangement and multiclonality in childhood leukaemia. Acta Paed, 83, 319-326.
17. Diaz, M.A., Garcia-Sanchez, F., Vivario, J.L., Ramirez, M., Balas, A. and Madero, L. (1997). Clinical relevance of T-cell receptor delta gene rearrangements in chidhood B-precursor cell acute lymphoblastic leukaemia. Br J Haematol, 99, 308-313.
18. Szczepanski, T., Beishuizen, A., Pongers-Willemse, M.J., Hahlen, K., Van wering, E.R., Wijkhuijs, A.J.M., Tibbe, G.J.M., Debrujin, M.A.C. and Vandongen, J.J.M. (1999). Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute leukaemias: alternative PCR target for detection of minimal residual disease. Leukemia, 13, 196-205.
19. Baruchel, A., Cayuela, J.M., Macintyre, E., Berger, R. and Sigah, F. (1995). Assessment of clonal evolution at Ig/TCR loci in acute lymphoblastic leukaemia by single-strand conformation polymorphism studies and highly resolutive PCR derived methods: implication for a general strategy of minimal residual disease detection. Br J Haematol, 90, 85-93.
20. Kitchingman, G.R., Mirro, J., Stass, S., Rovigatti, U., Melvin, S.L., Williams, D.L., Raimondi, S.C. and Murphey, S. (1986). Biologic and prognostic significance of the presence of more than two heavy-chain genes in childhood acute lymphoblastic leukemia of B precursor cell origin. Blood, 67, 698-703.
21. Beishuizen, A., Hahlen, K., Hagemeijer, A., Verhoeven, MA. J., Hooijkaas, H., Adriaansen, H.J., Wolvers-Tettero, L.M., Vanwering, E.R. and Vandongen, J.J.M. (1991). Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukaemia of B precursor origin. Leukemia, 5, 657-667.
22. Bird, J., Galili, N., Link, M., Stites, D., and Sklar, J. (1988). Continuing rearrangement but absence of somatic hypermutation im immunoglobulin genes of human B cell precursor leukaemia. J Exp Med, 168, 229-245.
23. Deane, M., Pappas, H. and Norton, J.D. (1991). Immunoglobulin heavy chain gene fingerprinting reveals widespread oligoclonality in B lineage acute lymphoblastic leukaemia. Leukemia, 5, 832-838.
24. Bunin, N.J., Raimondi, S.C., Mirro, J. JR, Behm, F.G., Goorha, R. and Kitchingman, G.R. (1990). Alterations in immunoglobulin or T cell receptor gene rearrangement at relapse: involvement of 11q23 and changes in immunophenotype. Leukemia, 4, 727-731.
25. H-D junctional diversity at diagnosis in patients with acute lymphoblastic leukaemia. Blood, 81, 775-782.
26. Davi, F., Gocke, C., Smith, S. and Sklar, G. (1996). Lymphocyte progenitor cell origin and clonal evolution of human B-lineage acute lymphoblastic leukaemia. Blood, 88, 609-621.
27. Steenbergen, E.J., Verhagen, O.J.H.M., Vanleeuwen, E.F., Vondemborne, A.E.G.K. and Vanderschoot, C.E (1993). Distinct ongoing Ig heavy chain rearrangement processes in childhood B-precursor acute lymphoblastic leukaemia. Blood, 82, 581-589.
28. H gene rearrangement events can modify the immunoglobulin heavy chain during progression of B lineage acute lymphoblastic leukemia. Blood, 79, 223-228.
29. Hendrickson, E.A., Liu, V.F. and Weaver, D.T. (1991). Strand breaks without DNA rearrangement in V(D)J recombination. Mol Cell Path, 11, 3155-3162.
30. Lewis, S.M. and Hesse, J.E. (1991) Cutting and closing without recombination in V(D)J joining. EMBO, 10, 3631-3639.
31. Yokota, S., Hansen-Hagge, T.E., Ludwig, W.D., Reiter, A., Raghavachar, A., Kleihauer, E. and Bartram, C.R. (1991). Use of polymerase chain reaction to monitor minimal residual disease in acute lymphoblastic leukaemia patients. Blood, 77, 331-339.
32. Deane, M., McCarthy, KP., Wiedemann, L.M. and Norton, J.D. (1991). An improved method for detection of B-lymphoid clonality by polymerase chain reaction. Leukemia, 5, 726-730.
33. Wasserman, R., Galili, N., Ito, Y., Silver, J.H., Reichard, B.A., Shane, S., Womer, R., Lange, B. and Rovera, G. (1992). Residual disease at the end of induction therapy as a predictor of relapse during therapy in childhhod B-lineage acute lymphoblastic leukaemia. J Clin Oncol, 10, 1879-1888.
34. Vandongen, J.J.M., Breit, T., Adriaansen, H.J., Beishuizen, A. and Hooijkaas, H. (1992). Detection of minimal residual disease in acute leukaemia by immunological marker analysis and polymerase chain reaction. Leukemia, 6, 47-59.
35. Foroni, L., Coyle, L.A., Papaioannou, M., Yaxley JC, Cole Sinclair MF, Chim JS, Cannell P, Secker-Waker LM, Mehta AB, Prentice HG and Hoffbrand AV (1997) Molecular detection of minimal residual disease in adult and childhood leukaemia reveals differences in treatment response. Leukemia, 11, 1732-1741.
36. Brisco, M.J., Condon, J., Hughes, E., Neoh, S.H., Sykes, P.J., Seshardi, I.T., Waters, K., Tauro, G., Ekert, H. and Morley, A.A. (1994). Outcome prediction in childhood acute lymphoblastic leukaemia by molecular quantification of residual disease at the end of induction. Lancet, 343, 196-200.
37. Lombard, J.F., Hwang, T.S., Russell, L.M., Millson, A. and Segal, G.H. (1996). Optimal selection for clonality. Assessment by polymerase chain reaction nalysis. III Intermediate and high grade B-cell neoplasm. Human Path, 27, 373-380.
38. Roberts, W.M., Estrov, Z., Ouspenskaia, M.V., Johnston, D.A., McClain, K.L. and Zipf, T,F (1997). Measurement of residual leukemia during remission in childhood acute lymphoblastic leukemia. N Eng J Med, 336, 317-323.
39. Goulden, N.J., Knechtli, C.J., Garland, R.J., Langlands, K., Hancock, J.P., Potter, M.N., Steward, C.G. and Oakhill, A. (1998). Minimal residual disease analysis for the prediction of relapse in children with standard risk acute lymphoblastic leukaemia. Br J Haematol, 100, 235-244.
40. Jacquy, C., Delapaut, B., Vandaele, J., Vaerman, J.L., Zenebergh A., Brichard, B., Vermylen, C., Cornu, G. and Martiat, P. (1997). A prospective study of minimal residual disease in childhood B-lineage acute lymphoblastic leukaemia: MRD level at the end of induction is a strong predictive factor of relapse. Br J Haematol, 98, 140-146.
41. Breit, T.M., Wolvers-Tettero, I.L.M., Hahlen, K., Van Wering, E.R., Van Dongen, J.J.M. (1991). Extensive junctional diversity of γδ T-cell receptor expressed by T-cell acute lymphoblastic leukaemias: implications for the detection of minimal residual disease. Leukemia, 5, 1076-1086.
42. Cave, H., Guidal, C., Rohrlich, P., Delfau, M.H., Broyart, A., Lescoeur, B., Rahimu, C., Fenneteau, O., Monplaisir, N., Dauriol, L., Elion, J., Vilmer, E. and Grandchamp, B. (1994). Prospective monitoring and quqntitation of residual blasts in childhood acute lymphoblastic leukaemia by polymerase chain reaction. Study of δ and γ T-cell receptor genes. Blood, 83, 1892-1902.
43. Steenbergen, E.J., Verhagen. O.J.H.M, Vanleeuwen E.F., Vandenberg, H., Von demborne, A.E.G.K., and Vanderschoot, C.E. (1995). Frequent ongoing T-cell receptor rearrangements in childhood B-precursor acute lymphoblastic leukemia: implications for monitoring minimal residual disease. Blood, 86, 692-702.
44. Cave, H., Vanderwerff, B.J., Suciu, S., Guidal, C., Waterkeyn, C., Otten, J., Bakkus, M., Thielemans, K., Grandchamp, B. and Vilmer, E. (1998). Clinical significance of minimal residual disease in childhood lymphoblastic leukaemia. Lancet, 339, 591-598.
45. Chessells, J.M., Bailey, C. and Richards, S.M. (1995). Intensification of treatment and survival in all children with lymphoblastic leukaemia: results of UK Medical Research Council Trial UKALL X. Lancet, 345, 143-148.
46. Chessells, J.M., Richards, S.M., Bailey, C.C., Lilleyman, J.S. and Eden, O.B. (1995). Gender and treatment outcome in childhood lymphoblastic leukaemia: report from the MRC UKALL trials. Br J Haem, 89, 364-372.
47. Pinkel, D. (1996). Selecting treatment for children and cure of childhood acute leukaemia. J Clin Oncol, 14, 4-6.
48. Green, E., McConville, C.M., Powell, J., Darbyshire, P.J., Mann, J.R, Taylor, A.M.R. and Stankovic, T. (1998). Clonal diversity of Ig and T-cell -Receptor gene rearrangements identifies a subset of childhood B-precursor acute lymphoblastic leukaemia with increased risk of relapse Blood, 92, 952-958.
49. Stankovic, T., Darbyshire, P., Mann, J.R., Pomfret, M. and Taylor, A.M.R. (1992). Rapid production of diversity during the progression of a mixed lineage leukaemia. Leuk Res, 16, 993-1002.
50. Nigro, L.L., Cazzangia, G., Cataldo, A.D., Pannunzio, A., D'Aniello, E., Masera, G., Schiliro, G. and Biondi, A. (1999). Clonal stability in children with acute lymphoblastic leukaemia (ALL) who relapsed five or more years after diagnosis. Leukemia, 13, 190-195.
51. Yoneda, N., Tatsumi, E., Kawano, S., Matsuo, Y., Minowada, J. and Yamaguchi, N. (1993). Human recombination activating gene-in leukaemia/lymphoma cells: exspression depends on stage of lymphoid differentiation defined by phenotype and genotype. Blood, 82, 207-216.
52. Schlissel, M.S. and Baltimore, D. (1989). Activation of immunoglobulin kappa chain gene rearrangement correlates with the induction of germline kappa gene transcription. Cell, 58, 1001-1007.
53. Boehm, T., Buluwela, L., Williams, D., White, L. and Rabbitts, T.H. (1988). A cluster of chromosome 11p13 translocations found via distinct D-D and D-D-J rearrangements of the human T cell receptor delta chain gene. EMBO, 7, 2011-2017.
54. Critchlow, S.E. and Jackson, S.P. (1998). DNA end joining: from yeast to man. Trends Biochem Sci, 23, 394-398.
55. Taylor, A.M.R., Metcalfe, J.A., Thick, J. and Mak, Y-F. (1996) Leukaemia and lymphoma in ataxia telangiectasia, Blood, 87: 423-38.