메뉴 건너뛰기




Volumn 74, Issue 3, 2000, Pages 1178-1186

The E8E2C protein, a negative regulator of viral transcription and replication, is required for extrachromosomal maintenance of human papillomavirus type 31 in keratinocytes

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; REPRESSOR PROTEIN; VIRUS DNA;

EID: 0033982569     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.3.1178-1186.2000     Document Type: Article
Times cited : (114)

References (45)
  • 1
    • 0026695145 scopus 로고
    • Mechanism of action of the papillomavirus E2 repressor: Repression in the absence of DNA binding
    • Barsoum, J., S. Prakash, P. Han, and E. J. Androphy. 1992. Mechanism of action of the papillomavirus E2 repressor: repression in the absence of DNA binding. J. Virol. 66:3941-3945.
    • (1992) J. Virol. , vol.66 , pp. 3941-3945
    • Barsoum, J.1    Prakash, S.2    Han, P.3    Androphy, E.J.4
  • 2
    • 0025820471 scopus 로고
    • Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation
    • Bedell, M. A., J. B. Hudson, T. R. Golub, M. E. Turyk, M. Hosken, G. D. Wilbanks, and L. A. Laimins. 1991. Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation. J. Virol. 65:2254-2260.
    • (1991) J. Virol. , vol.65 , pp. 2254-2260
    • Bedell, M.A.1    Hudson, J.B.2    Golub, T.R.3    Turyk, M.E.4    Hosken, M.5    Wilbanks, G.D.6    Laimins, L.A.7
  • 3
    • 0027967461 scopus 로고
    • Characterization of the human papillomavirus E2 protein: Evidence of trans-activation and transrepression in cervical keratinocytes
    • Bouvard, V., A. Storey, D. Pim, and L. Banks. 1994. Characterization of the human papillomavirus E2 protein: evidence of trans-activation and transrepression in cervical keratinocytes. EMBO J. 13:5451-5459.
    • (1994) EMBO J. , vol.13 , pp. 5451-5459
    • Bouvard, V.1    Storey, A.2    Pim, D.3    Banks, L.4
  • 4
    • 0026000864 scopus 로고
    • An E1M^E2C fusion protein encoded by human papillomavirus type 11 is a sequence-specific transcription repressor
    • Chiang, C. M., T. R. Broker, and L. T. Chow. 1991. An E1M^E2C fusion protein encoded by human papillomavirus type 11 is a sequence-specific transcription repressor. J. Virol. 65:3317-3329.
    • (1991) J. Virol. , vol.65 , pp. 3317-3329
    • Chiang, C.M.1    Broker, T.R.2    Chow, L.T.3
  • 5
    • 0026806749 scopus 로고
    • Control of human papillomavirus type 11 origin of replication by the E2 family of transcription regulatory proteins
    • Chiang, C. M., G. Dong, T. R. Broker, and L. T. Chow. 1992. Control of human papillomavirus type 11 origin of replication by the E2 family of transcription regulatory proteins. J. Virol. 66:5224-5231.
    • (1992) J. Virol. , vol.66 , pp. 5224-5231
    • Chiang, C.M.1    Dong, G.2    Broker, T.R.3    Chow, L.T.4
  • 6
    • 0023770979 scopus 로고
    • Regulation of human papillomavirus type 11 enhancer and E6 promoter by activating and repressing proteins from the E2 open reading frame: Functional and biochemical studies
    • Chin, M. T., R. Hirochika, H. Hirochika, T. R. Broker, and L. T. Chow. 1988. Regulation of human papillomavirus type 11 enhancer and E6 promoter by activating and repressing proteins from the E2 open reading frame: functional and biochemical studies. J. Virol. 62:2994-3002.
    • (1988) J. Virol. , vol.62 , pp. 2994-3002
    • Chin, M.T.1    Hirochika, R.2    Hirochika, H.3    Broker, T.R.4    Chow, L.T.5
  • 7
    • 0024556457 scopus 로고
    • Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: Structural and functional analysis of new viral cDNAs
    • Choe, J. P., P. Vaillancourt, A., Stenlund, and M. Botchan. 1989. Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: structural and functional analysis of new viral cDNAs. J. Virol. 63:1743-1755.
    • (1989) J. Virol. , vol.63 , pp. 1743-1755
    • Choe, J.P.1    Vaillancourt, P.2    Botchan, M.3
  • 8
    • 0025148460 scopus 로고
    • Detection of novel splicing patterns in a HPV16-containing keratinocyte cell line
    • Doorbar, J., A. Parton, K. Hartley, L. Banks, T. Crook, M. Stanley, and L. Crawford. 1990. Detection of novel splicing patterns in a HPV16-containing keratinocyte cell line. Virology 178:254-262.
    • (1990) Virology , vol.178 , pp. 254-262
    • Doorbar, J.1    Parton, A.2    Hartley, K.3    Banks, L.4    Crook, T.5    Stanley, M.6    Crawford, L.7
  • 9
    • 0028054269 scopus 로고
    • The role of the E1 and E2 proteins in the replication of human papillomavirus type 31b
    • Frattini, M. G., and L. A. Laimins. 1994. The role of the E1 and E2 proteins in the replication of human papillomavirus type 31b. Virology 204:799-804.
    • (1994) Virology , vol.204 , pp. 799-804
    • Frattini, M.G.1    Laimins, L.A.2
  • 10
    • 0030745931 scopus 로고    scopus 로고
    • Induction of human papillomavirus type 18 late gene expression and genomic amplification in organotypic cultures from transfected DNA templates
    • Frattini, M. G., H. B. Lim, J. Doorbar, and L. A. Laimins. 1997. Induction of human papillomavirus type 18 late gene expression and genomic amplification in organotypic cultures from transfected DNA templates. J. Virol. 71:7068-7072.
    • (1997) J. Virol. , vol.71 , pp. 7068-7072
    • Frattini, M.G.1    Lim, H.B.2    Doorbar, J.3    Laimins, L.A.4
  • 11
    • 0029863784 scopus 로고    scopus 로고
    • In vitro synthesis of oncogenic human papillomaviruses requires episomal genomes for differentiation-dependent late expression
    • Frattini, M. G., H. B. Lim, and L. A. Laimins. 1996. In vitro synthesis of oncogenic human papillomaviruses requires episomal genomes for differentiation-dependent late expression. Proc. Natl. Acad. Sci. USA 93:3062-3067.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3062-3067
    • Frattini, M.G.1    Lim, H.B.2    Laimins, L.A.3
  • 12
    • 0023684064 scopus 로고
    • A general method of in vitro preparation and specific mutagenesis of DNA fragments: Study of protein and DNA interactions
    • Higuchi, R., B. Krummel, and R. K. Saiki. 1988. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res. 16:7351-7367.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 7351-7367
    • Higuchi, R.1    Krummel, B.2    Saiki, R.K.3
  • 14
    • 0032981466 scopus 로고    scopus 로고
    • DNA replication of human papillomavirus type 31 is modulated by elements of the upstream regulatory region that lie 5′ of the minimal origin
    • Hubert, W. G., T. Kanaya, and L. A. Laimins. 1999. DNA replication of human papillomavirus type 31 is modulated by elements of the upstream regulatory region that lie 5′ of the minimal origin. J. Virol. 73:1835-1845.
    • (1999) J. Virol. , vol.73 , pp. 1835-1845
    • Hubert, W.G.1    Kanaya, T.2    Laimins, L.A.3
  • 15
    • 0027502917 scopus 로고
    • The 23-kilodalton E1 phosphoprotein of bovine papillomavirus type 1 is nonessential for stable plasmid replication in murine C127 cells
    • Hubert, W. G., and P. F. Lambert. 1993. The 23-kilodalton E1 phosphoprotein of bovine papillomavirus type 1 is nonessential for stable plasmid replication in murine C127 cells. J. Virol. 67:2932-2937.
    • (1993) J. Virol. , vol.67 , pp. 2932-2937
    • Hubert, W.G.1    Lambert, P.F.2
  • 16
    • 0026671624 scopus 로고
    • Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes
    • Hummel, M., J. B. Hudson, and L. A. Laimins. 1992. Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes. J. Virol. 66:6070-6080.
    • (1992) J. Virol. , vol.66 , pp. 6070-6080
    • Hummel, M.1    Hudson, J.B.2    Laimins, L.A.3
  • 17
    • 0028937867 scopus 로고
    • Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells
    • Jeon, S., B.-L. Allen-Hoffmann, and P. F. Lambert. 1995. Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells. J. Virol. 69:2989-2997.
    • (1995) J. Virol. , vol.69 , pp. 2989-2997
    • Jeon, S.1    Allen-Hoffmann, B.-L.2    Lambert, P.F.3
  • 18
    • 0027270470 scopus 로고
    • Identification and characterization of novel promoters in the genome of human papillomavirus type 18
    • Karlen, S., and P. Beard. 1993. Identification and characterization of novel promoters in the genome of human papillomavirus type 18. J. Virol. 67: 4296-4306.
    • (1993) J. Virol. , vol.67 , pp. 4296-4306
    • Karlen, S.1    Beard, P.2
  • 19
    • 0030267240 scopus 로고    scopus 로고
    • Human papillomaviruses target differentiating epithelium for virion production and malignant conversion
    • Laimins, L. A. 1996. Human papillomaviruses target differentiating epithelium for virion production and malignant conversion. Semin. Virol. 7:305-313.
    • (1996) Semin. Virol. , vol.7 , pp. 305-313
    • Laimins, L.A.1
  • 20
    • 0023643049 scopus 로고
    • A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator
    • Lambert, P. F., B. A. Spalholz, and P. M. Howley. 1987. A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator. Cell 50:69-78.
    • (1987) Cell , vol.50 , pp. 69-78
    • Lambert, P.F.1    Spalholz, B.A.2    Howley, P.M.3
  • 21
    • 0024399392 scopus 로고
    • Genetic assignment of multiple E2 gene products in bovine papillomavirus-transformed cells
    • Lambert, P. F., N. L. Hubbert, P. M. Howley, and J. T. Schiller. 1989. Genetic assignment of multiple E2 gene products in bovine papillomavirus-transformed cells. J. Virol. 63:3151-3154.
    • (1989) J. Virol. , vol.63 , pp. 3151-3154
    • Lambert, P.F.1    Hubbert, N.L.2    Howley, P.M.3    Schiller, J.T.4
  • 22
    • 0025141762 scopus 로고
    • Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants
    • Lambert, P. F., B. C. Monk, and P. M. Howley. 1990. Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants. J. Virol. 64:950-956.
    • (1990) J. Virol. , vol.64 , pp. 950-956
    • Lambert, P.F.1    Monk, B.C.2    Howley, P.M.3
  • 23
    • 0030901534 scopus 로고    scopus 로고
    • A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention
    • Lehman, C. W., D. S. King, and M. R. Botchan. 1997. A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention. J. Virol. 71: 3652-3665.
    • (1997) J. Virol. , vol.71 , pp. 3652-3665
    • Lehman, C.W.1    King, D.S.2    Botchan, M.R.3
  • 24
    • 0031911644 scopus 로고    scopus 로고
    • Competition for DNA binding sites between the short and long forms of E2 dimers underlies repression in bovine papillomavirus type 1 DNA replication control
    • Lim, D. A., M. Gossen, C. W. Lehman, and M. R. Botchan. 1998. Competition for DNA binding sites between the short and long forms of E2 dimers underlies repression in bovine papillomavirus type 1 DNA replication control. J. Virol. 72:1931-1940.
    • (1998) J. Virol. , vol.72 , pp. 1931-1940
    • Lim, D.A.1    Gossen, M.2    Lehman, C.W.3    Botchan, M.R.4
  • 25
    • 0028805789 scopus 로고
    • The functions of human papillomavirus type 11 E1, E2, and E2C proteins in cell-free DNA replication
    • Liu, J. S., S.-R. Kuo, T. R. Broker, and L. T. Chow. 1995. The functions of human papillomavirus type 11 E1, E2, and E2C proteins in cell-free DNA replication. J. Biol. Chem. 270:27283-27291.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27283-27291
    • Liu, J.S.1    Kuo, S.-R.2    Broker, T.R.3    Chow, L.T.4
  • 26
    • 0025953354 scopus 로고
    • The papillomavirus E2 regulatory proteins
    • McBride, A. A., H. Romanczuk, and P. M. Howley. 1991. The papillomavirus E2 regulatory proteins. J. Biol. Chem. 266:18411-18414.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18411-18414
    • McBride, A.A.1    Romanczuk, H.2    Howley, P.M.3
  • 27
    • 1842367150 scopus 로고
    • E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: Transactivation is mediated by the conserved amino-terminal domain
    • McBride, A. A., J. C. Byrne, and P. M. Howley. 1989. E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc. Natl. Acad. Sci. USA 86:510-514.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 510-514
    • McBride, A.A.1    Byrne, J.C.2    Howley, P.M.3
  • 28
    • 0025757388 scopus 로고
    • Bovine papillomavirus with a mutation in the E2 serine 301 phosphorylation site replicates at a high copy number
    • McBride, A. A., and P. M. Howley. 1991. Bovine papillomavirus with a mutation in the E2 serine 301 phosphorylation site replicates at a high copy number. J. Virol. 65:6528-6534.
    • (1991) J. Virol. , vol.65 , pp. 6528-6534
    • McBride, A.A.1    Howley, P.M.2
  • 29
    • 0026671476 scopus 로고
    • Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation
    • Meyers, C., M. G. Frattini, J. B. Hudson, and L. A. Laimins. 1992. Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation. Science 257:971-973.
    • (1992) Science , vol.257 , pp. 971-973
    • Meyers, C.1    Frattini, M.G.2    Hudson, J.B.3    Laimins, L.A.4
  • 30
    • 0030820343 scopus 로고    scopus 로고
    • Synthesis of infectious human papillomavirus type 18 in differentiating epithelium transfected with viral DNA
    • Meyers, C., T. J. Mayer, and M. A. Ozbun. 1997. Synthesis of infectious human papillomavirus type 18 in differentiating epithelium transfected with viral DNA. J. Virol. 71:7381-7386.
    • (1997) J. Virol. , vol.71 , pp. 7381-7386
    • Meyers, C.1    Mayer, T.J.2    Ozbun, M.A.3
  • 31
    • 0032169835 scopus 로고    scopus 로고
    • Human papillomavirus type 31b E1 and e2 transcript expression correlates with vegetative viral genome amplification
    • Ozbun, M. A., and C. Meyers. 1998. Human papillomavirus type 31b E1 and E2 transcript expression correlates with vegetative viral genome amplification. Virology 248:218-230.
    • (1998) Virology , vol.248 , pp. 218-230
    • Ozbun, M.A.1    Meyers, C.2
  • 32
    • 0031925584 scopus 로고    scopus 로고
    • Temporal usage of multiple promoters during the life cycle of human papillomavirus type 31b
    • Ozbun, M. A., and C. Meyers. 1998. Temporal usage of multiple promoters during the life cycle of human papillomavirus type 31b. J. Virol. 72:2715-2722.
    • (1998) J. Virol. , vol.72 , pp. 2715-2722
    • Ozbun, M.A.1    Meyers, C.2
  • 33
    • 0030048803 scopus 로고    scopus 로고
    • Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator
    • Piirsoo, M., E. Ustav, T. Mandel, A. Stenlund, and M. Ustav. 1996. Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator. EMBO J. 15:1-11.
    • (1996) EMBO J. , vol.15 , pp. 1-11
    • Piirsoo, M.1    Ustav, E.2    Mandel, T.3    Stenlund, A.4    Ustav, M.5
  • 34
    • 0032975255 scopus 로고    scopus 로고
    • Human papillomavirus type 18 E1 protein is translated from polycistronic mRNA by a discontinuous scanning mechanism
    • Remm, M., A. Remm, and M. Ustav. 1999. Human papillomavirus type 18 E1 protein is translated from polycistronic mRNA by a discontinuous scanning mechanism. J. Virol. 73:3062-3070.
    • (1999) J. Virol. , vol.73 , pp. 3062-3070
    • Remm, M.1    Remm, A.2    Ustav, M.3
  • 35
    • 0019471387 scopus 로고
    • Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas
    • Rheinwald, J. G., and M. A. Beckett. 1981. Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas. Cancer Res. 41:1657-1663.
    • (1981) Cancer Res. , vol.41 , pp. 1657-1663
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 36
    • 0025169842 scopus 로고
    • Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity
    • Riese, D. J., II, J. Settleman, K. Neary, and D. DiMaio. 1990. Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity. J. Virol. 64:944-949.
    • (1990) J. Virol. , vol.64 , pp. 944-949
    • Riese D.J. II1    Settleman, J.2    Neary, K.3    DiMaio, D.4
  • 37
    • 0024407710 scopus 로고
    • Characterization of rare human papillomavirus type 11 mRNAs coding for regulatory and structural proteins, using the polymerase chain reaction
    • Rotenberg, M. O., L. T. Chow, and T. R. Broker. 1989. Characterization of rare human papillomavirus type 11 mRNAs coding for regulatory and structural proteins, using the polymerase chain reaction. Virology 172:489-497.
    • (1989) Virology , vol.172 , pp. 489-497
    • Rotenberg, M.O.1    Chow, L.T.2    Broker, T.R.3
  • 38
    • 0026576820 scopus 로고
    • Human papillomavirus type 33 in a tonsillar carcinoma generates its putative E7 mRNA via two E6* transcript species which are terminated at different early region poly(A) sites
    • Snijders, P. J., A. J. C. van den Brule, H. F. Schrijnemakers, P. M. Raaphorst, C. J. Meijer, and J. M. Walboomers. 1992. Human papillomavirus type 33 in a tonsillar carcinoma generates its putative E7 mRNA via two E6* transcript species which are terminated at different early region poly(A) sites. J. Virol. 66:3172-3178.
    • (1992) J. Virol. , vol.66 , pp. 3172-3178
    • Snijders, P.J.1    Van Den Brule, A.J.C.2    Schrijnemakers, H.F.3    Raaphorst, P.M.4    Meijer, C.J.5    Walboomers, J.M.6
  • 39
    • 0002532879 scopus 로고    scopus 로고
    • Papillomavirus DNA replication
    • M. L. DePamphilis (ed.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Stenlund, A. 1996. Papillomavirus DNA replication, p. 679-698. In M. L. DePamphilis (ed.), DNA replication in eukaryotic cells. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1996) DNA Replication in Eukaryotic Cells , pp. 679-698
    • Stenlund, A.1
  • 40
    • 0031931726 scopus 로고    scopus 로고
    • Differential requirements for conserved E2 binding sites in the life cycle of oncogenic human papillomavirus type 31
    • Stubenrauch, F., H. B. Um, and L. A. Laimins. 1998. Differential requirements for conserved E2 binding sites in the life cycle of oncogenic human papillomavirus type 31. J. Virol. 72:1071-1077.
    • (1998) J. Virol. , vol.72 , pp. 1071-1077
    • Stubenrauch, F.1    Um, H.B.2    Laimins, L.A.3
  • 41
    • 0031687934 scopus 로고    scopus 로고
    • Transactivation by the E2 protein of oncogenic human papillomavirus type 31 is not essential for early and late viral functions
    • Stubenrauch, F., A. M. Colbert, and L. A. Laimins. 1998. Transactivation by the E2 protein of oncogenic human papillomavirus type 31 is not essential for early and late viral functions. J. Virol. 72:8115-8123.
    • (1998) J. Virol. , vol.72 , pp. 8115-8123
    • Stubenrauch, F.1    Colbert, A.M.2    Laimins, L.A.3
  • 42
    • 0033587681 scopus 로고    scopus 로고
    • Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes
    • Thomas, J. T., W. G. Hubert, M. N. Ruesch, and L. A. Laimins. 1999. Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes. Proc. Natl. Acad. Sci. USA 96:8449-8454.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8449-8454
    • Thomas, J.T.1    Hubert, W.G.2    Ruesch, M.N.3    Laimins, L.A.4
  • 43
    • 0024043266 scopus 로고
    • The product of the bovine papillomavirus type 1 modulator gene (M) is a phosphoprotein
    • Thorner, L., N. Bucay, J. Choe, and M. Botchan. 1988. The product of the bovine papillomavirus type 1 modulator gene (M) is a phosphoprotein. J. Virol. 62:2474-2482.
    • (1988) J. Virol. , vol.62 , pp. 2474-2482
    • Thorner, L.1    Bucay, N.2    Choe, J.3    Botchan, M.4
  • 44
    • 0026034125 scopus 로고
    • Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames
    • Ustav, M., and A. Stenlund. 1991. Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. EMBO J. 10:449-457.
    • (1991) EMBO J. , vol.10 , pp. 449-457
    • Ustav, M.1    Stenlund, A.2
  • 45
    • 0028348414 scopus 로고
    • Molecular pathogenesis of cancer of the cervix and its causation by specific human papillomavirus types
    • H. zur Hausen (ed.). Springer-Verlag KG, Berlin, Germany
    • zur Hausen, H. 1994. Molecular pathogenesis of cancer of the cervix and its causation by specific human papillomavirus types, p. 131-156. In H. zur Hausen (ed.), Human pathogenic papillomaviruses. Springer-Verlag KG, Berlin, Germany.
    • (1994) Human Pathogenic Papillomaviruses , pp. 131-156
    • Zur Hausen, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.