The application of predictive models in the environmental risk assessment of ECONOR

Chemosphere

Volumn 40, Issue 7, 2000, Pages 775-781

  Boxall, A B A ^a   Oakes, D ^a   Ripley, P ^b   Watts, C D ^a  

^a WRC PLC   (United Kingdom)

^b Novartis Animal Health UK Ltd   (United Kingdom)

Author keywords

ECONOR; Environmental risk assessment; QSAR; Tiamulin; Valnemulin

Indexed keywords

TIAMULIN; UNCLASSIFIED DRUG; VALNEMULIN; VETERINARY DRUG;

ARTICLE; BIODEGRADATION; DRUG DEGRADATION; ECOTOXICITY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RISK ASSESSMENT; SOIL POLLUTION; WATER CONTAMINATION;

DITERPENES; ENVIRONMENTAL MONITORING; FRESH WATER; MODELS, BIOLOGICAL; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; SOIL POLLUTANTS; STRUCTURE-ACTIVITY RELATIONSHIP; WATER POLLUTANTS, CHEMICAL;

EID: 0033981492     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0045-6535(99)00452-X     Document Type: Article

References (13)

1. Boethling R.S., Howard P.H., Meylan W., Stiteler W., Beaumann J., Tirado N. Group contribution method for predicting probability and rate of aerobic degradation. Environ. Sci. Technol. 28:1994;459-465.
2. Committee for Veterinary Medicinal Products, 1996. Note for guidance: environmental risk assessment for veterinary medicinal products other than GMO-containing and immunological products EMEA/CVMP/055/96-Final. European Agency for Evaluation of Medicinal Products, London, UK.
3. Howard P.H., Boethling R.S., Stiteler W.M., Hueber A.E., Beaumann J.A., Larosche M.E. Predictive model for aerobic biodegradability developed from a file of evaluated biodegradation data. Environ. Toxicol. Chem. 11:1992;593-693.
4. Howard, P.H., Meylan, W.M., 1997. Prediction of physical properties, transport and degradation for environmental fate and exposure assessments. In: Chen, F., Schuurmann, G. (Eds.). Quantitative Structure-Activity Relationships in Environmental Sciences VII. SETAC Press, Pensacola, FL, USA.
5. Karickhoff S.W. Semi-empirical estimation of sorption of hydrophobic pollutants on natural sediments and soils. Chemosphere. 10(8):1981;833-846.
6. Mackay, D., 1991. Multimedia Environmental Fate Models: The Fugacity Approach. Lewis, Chelsea, MI, USA.
7. Meylan W.M., Howard P.H. Bond contribution method for estimating Henry's law constants. Environ. Toxicol. Chem. 10:1991;1283-1293.
8. Oakes, D., 1988. Prediction of pesticide pollution in the environment - the PESTCAT and PESTAQ models. WRc Report No. CO4502. WRc, Marlow, Buckinghamshire, UK.
9. OECD, 1995. OECD Environment Monographs No.92. Guidance document for aquatic effects assessment. OECD, Paris, France.
10. Royal Society of Chemistry, 1991. The Agrochemicals Handbook, third addition. Royal Society of Chemistry, Cambridge, UK.
11. Spaepen K.R.I., Leemput L.J.J., Wislock P.G., Verscheuren C. A uniform approach to estimate the predicted environmental concentrations of the residues of veterinary medicines in soil. Environ. Toxicol. Chem. 16(9):1997;1977-1982.
12. Turner L., Choplin F., Dugard P., Hermens J., Jaekh R., Marsmann M., Roberts D. Structure-activity relationships in toxicology and ecotoxicology: an assessment. Toxic. in vitro. 1(3):1987;143-171.
13. USEPA., 1994. ECOSAR - a program for estimating the aquatic toxicity of industrial chemicals, Version 1.01. USEPA, Washington DC, USA.