Gastroprotective effect of essential oil from Croton cajucara Benth. (Euphorbiaceae)

Journal of Ethnopharmacology

Volumn 69, Issue 3, 2000, Pages 229-234

  Hiruma Lima, C A ^a,b   Gracioso, J S ^b   Rodriguez J A ^b,c   Haun, M ^b   Nunes, D S ^d   Souza Brito, A R M ^b  

^a Fund Univ Estadual de Tocantins   (Brazil)

^b INSTITUTO BIOLÓGICO   (Brazil)

^c UNIVERSIDAD DE TALCA   (Chile)

^d FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

Antiulcerogenic activity; Croton cajucara; Essential oil; Euphorbiaceae; In vivo and in vitro toxicity

Indexed keywords

ALCOHOL; CIMETIDINE; CROTON EXTRACT; ESSENTIAL OIL; HYDROCHLORIC ACID; ILZATEC; INDOMETACIN; LANSOPRAZOLE; OMEPRAZOLE; POLYSORBATE 80; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CHINESE HAMSTER; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; EUPHORBIA; HYPOTHERMIA; IC 50; IN VITRO STUDY; IN VIVO STUDY; LD 50; LUNG FIBROBLAST; MALE; MOUSE; NONHUMAN; STOMACH ACID; STOMACH PH; STOMACH SECRETION; STOMACH ULCER; STRESS; ULCEROGENESIS;

ANIMALS; CELL LINE; CELL SURVIVAL; CRICETINAE; EUPHORBIACEAE; LETHAL DOSE 50; MICE; OILS, VOLATILE; STOMACH; STOMACH ULCER;

EID: 0033981449     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(99)00127-0     Document Type: Article

References (21)

1. al-Shabanah O.A. Effect of evening primrose oil on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats. Food Chem. Toxicol. 35:1997;769-775.
2. Bianchi V., Fortunati E. Cellular effects of an anionic surfactant detected in V79 fibroblasts by different cytotoxicity tests. Toxicol. In Vitro. 4:1990;9-16.
3. Cingi M.R., De Angelis I., Fortunati E., Reggiani D., Bianchi V., Tiozzo R., Zucco F. Choice and standardization of test protocols in cytotoxicology: a multicentre approach. Toxicol. In Vitro. 5:1991;119-125.
4. Di Stasi, L.C., Santos, E.M.G., Santos, C.M., Hiruma, C.A., 1989. Plantas Medicinais da Amazônia, Ed. UNESP, São Paulo, 194 p.
5. Goa K.L., Monk J.P. Enprostil: a preliminary review of its pharmacodynamics and pharmacokinetics properties and therapeutic efficacy in the treatment of peptic ulcer disease. Drugs. 3:1987;539-559.
6. Guth P.H. Gastric blood flow in restraint stress. Dig. Dis. 17:1972;807-813.
7. Kitagawa H., Fujwara M., Osumi Y. Effect of water immersion stress on gastric secretion and mucosal blood flow in rats. Gastroenterology. 77:1979;298-302.
8. Koo M.W.L., Ogle C.W., Cho C.H. Effect of verapamil, carbenoxolone and N-acetyl-cysteine on gastric wall mucus and ulceration in stressed rats. Pharmacology. 32:1986;326-334.
9. Levine R.J. A method for rapid production of stress ulcers in rats. Pfeiffer C.J. Peptic Ulcer. 1971;92-97 Munksgaard, Copenhagen.
10. Lewis D.A., Hanson P.J. Anti-ulcer drugs of plant origin. Ellis G.P., West G.B. Progress in Medicinal Chemistry. 28:1991;201-301 Elsevier Science B.V.
11. Litchfield J.T. Jr, Wilcoxon F. A simplified method of evaluating dose-effect experiments. J. Pharmacol. Exp. Ther. 96:1949;99-113.
12. Lloris J.M., Bolant B., Gimeno L., Cejalvo D., Gimeno L.O., Calvo M.A., Perkins I. Gastric juice and analysis of basal and stimulated secretion following treatment with rice-bran oil. Res. Commun. Chem. Pathol. Pharmacol. 74:1991;245-248.
13. Oates P.J., Hakkinen J.P. Studies on the mechanism of ethanol-induced gastric damage in rats. Gastroenterology. 94:1988;10-21.
14. Phillips B. Development of cell culture techniques for assessment of the toxicity of plant products. Toxicol. In Vitro. 10:1996;69-76.
15. Robert A., Nezamis J.E., Lancaster C., Hanchar A.L. Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl and thermal injury. Gastroenterology. 77:1979;433-443.
16. Ross S.A., el Sayed K.A., el Sohly M.A., Hamann M.T., Abdel-Halim O.B., Ahmed A.F., Ahmed M.M. Phytochemical analysis of Geigeria alata and Francoeuria crispa essential oils. Planta Medica. 63:1997;479-482.
17. Shay H., Komarov S.A., Fels S.S., Meranze D., Gruenstein M., Siplet H. A simple method for the uniform production of gastric ulceration in the rat. Gastroenterology. 5:1945;43-61.
18. Souza Brito A.R.M., Rodríguez J.A., Hiruma-Lima C.A., Haun M., Nunes D.S. Anti-ulcerogenic activity of dehydrocrotonin, a diterpene isolated from Croton cajucara Benth. Planta Med. 64:1998;126-129.
19. Van den Berg, M.E., 1982. Plantas medicinais da Amazônia-Contribuição ao seu conhecimento sistemático, Museu Paraense Emílio Goeldi, Belém, 223 p.
20. Watanabe K. Some pharmacological factors involved in formation and prevention of stress ulcers in rats. Chem. Pharm. Bull. 14:1966;101-107.
21. Yesilada E., Gurbuz I., Ergun E. Effects of Cistus laurifolius L. flowers on gastric and duodenal lesions. J. Ethnopharmacol. 55:1997;201-211.