Clonal heterogeneity in sporadic melanomas as revealed by loss-of- heterozygosity analysis

International Journal of Cancer

Volumn 85, Issue 4, 2000, Pages 492-497

  Takata, Minoru ^a   Morita, Reiji ^a   Takehara, Kazuhiko ^a  

^a KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 10Q; CHROMOSOME 18Q; CHROMOSOME 6Q; CHROMOSOME 9P; GENETIC LINKAGE; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MELANOMA; MOLECULAR CLONING; PRIORITY JOURNAL; SKIN CARCINOGENESIS;

EID: 0033980612     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0215(20000215)85:4<492::aid-ijc8>3.0.co;2-%23     Document Type: Article

References (20)

1. BOENI, R., MATT, D., VOETMEYER, A., BURG, G. and ZHUANG, Z., Chromosomal allelic loss in primary cutaneous melanoma is heterogeneous and correlates with proliferation. J. invest. Dermatol. 110, 215-217 (1998).
2. DRACOPOLI, N.C., ALHADEFF, B., HOUGHTON, A.N. and OLD, L.J., Loss of heterozygosity at autosomal and X-linked loci during tumor progression in a patient with melanoma. Cancer Res., 47, 3995-4000 (1987).
3. FIDLER, I.J., Critical determinants of melanoma metastasis. J. invest. Dermatol. Symp. Proc., 1, 203-208 (1996).
4. FIELD, J.K. and 12 OTHERS, Allelotype of squamous-cell carcinoma of the head and neck: fractional allele loss correlates with survival. Brit. J. Cancer, 72, 1180-1188 (1995).
5. INK4A inactivation is not frequent in uncultured sporadic primary cutaneous melanoma. Oncogene, 18, 2527-2532 (1999).
6. GIERCKSKY, H.E., THORSTENSEN, L., QVIST, H., NESLAND, J.M. and LOTHE, R.A., Comparison of genetic changes in frozen biopsies and microdissected archival material from the same colorectal liver metastases. Diagn. mol. Pathol., 6, 318-325 (1997).
7. HEALY, E., BELGAID, C.E., TAKATA, M., HARRISON, D., ZHU, N.W., BURD, D.A., RIGBY, H.S., MATTHEWS, J.N. and REES, J.L., Prognostic significance of allelic losses in primary melanoma. Oncogene, 16, 2213-2218 (1998).
8. HEALY, E., BELGAID, C.E., TAKATA, M., VAHLQUIST, A., REHMAN, I., RIGBY, H. and REES, J.L., Allelotypes of primary cutaneous melanoma and benign melanocytic nevi. Cancer Res., 56, 589-59 (1996).
9. JEN, J., KIM, H., PIANTADOSI, S., LIU, Z.F., LEVITT, R.C., SISTONEN, P., KINSLER, K.W., VOGELSTEIN, B. and HAMILTON, S.R., Allelic loss of chromosome 18q and prognosis in colorectal cancer. New Engl. J. Med., 331, 213-221 (1994).
10. KUUKASJARVI, T., KARHU, R., TANNER, M., KAHKONEN, M., SCHAFFER, A., NUPPONEN, N., PENNANEN, S., KALLIONIEMI, A., KALLIONIEMI, O-P. and ISOLA, J., Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer. Cancer Res., 57, 1597-1604 (1997).
11. LEE, J.H., MIELE, M.E., HICKS, D.J., PHILLIPS, K.K., TRENT, J.M., WEISSMAN, B.E. and WELCH, D.R., KiSS-1, a novel human-malignant-melanoma-metastasis-suppressor gene. J. nat. Cancer Inst., 88, 1731-1737 (1996).
12. MORITA, R., FUJIMOTO, A., HATTA, N., TAKEHARA, K. and TAKATA, M., Comparison of genetic profiles between primary melanomas and their metastases reveals genetic alterations and clonal evolution during progression. J. invest. Dermatol., 111, 919-924 (1998).
13. NOWELL, P.C., The clonal evolution of tumor-cell populations. Science, 194, 23-28 (1976).
14. RAY, M.E., SU, Y.A., MELTZER, P.S. and TRENT, J.M., Isolation and characterization of genes associated with chromosome-6-mediated tumor suppression in human malignant melanoma. Oncogene, 12, 2527-2533 (1996).
15. ROBERTSON, G.P., COLEMAN, A.B. and LUGO, T.G., Mechanisms of human melanoma cell growth and tumor suppression by chromosome 6. Cancer Res., 56, 1635-1641 (1996).
16. THEILI, M., SEITZ, S., ARNOLD, W., JANDRIG, B., FREGE, R., SCHLAG, P.M., HAHNSCH, W., GUSKI, H., WINZER, K.J., BARRET, J.C. and SCHERNECK, S.A., Defined chromosome 6q fragment (at D6S310) harbors a putative tumor-suppressor gene for breast cancer. Oncogene, 13, 677-685 (1996).
17. TOLLENAAR, R.A., BONSING, B.A., KUIPERS-DUKSHOORN, N.J., HERMANS, J., VAN DE VELDE, C.J., CORNELISSE, C.J. and FLEUREN, G.J., Evidence of clonal divergence in colorectal carcinoma. Cancer, 79, 1304-1314 (1997).
18. WAN, M., SUN, T., VYAS, R., ZHENG, J., GRANADA, E. and DUBEAU, L., Suppression of tumorigenicity in human ovarian-cancer cell lines is controlled by a 2-cM fragment in chromosomal region 6q24-q25. Oncogene, 18, 1545-1551 (1999).
19. WELCH, D.R., CHEN, P., MIELE, M.E., MCGARY, C.T., BOWER, J.M., STANBRIDGE, E.J. and WEISSMAN, B.E., Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity. Oncogene, 9, 255-262 (1994).
20. WEST, A., VOJTA, P.J., WELCH, D.R. and WEISSMAN, B.E., Chromosome localisation and genomic structure of the KiSS-1 metastasis-suppressor gene (KISS1). Genomics, 54, 145-148 (1998).