A facile and convenient synthetic method for fluorine-containing 1h-pyrrolo[3, 2-a]quinolines

Heterocycles

Volumn 53, Issue 1, 2000, Pages 127-134

  Okada, Etsuji ^a   Tsukushi, Norikado ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PYRROLE DERIVATIVE; QUINOLINE DERIVATIVE; TUBERCULOSTATIC AGENT;

ARTICLE; CHROMATOGRAPHY; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; MELTING POINT; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0033979659     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-99-8738     Document Type: Article

References (7)

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2. E. Okada and N. Tsukushi, Synlett, 1999, 210.
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5. M.G. Ferlin, G. Chiarelotto, F. Baccichetti, F. Carlassare, L. Toniolo, and F. Bordin, Farmaco, 1992, 47, 1513.
6. J.C. del Valle, E. Dominguez, and M. Kasha, J. Phys. Chem. A, 1999, 103, 2467 and references cited therein.
7. Proportions of the two stereoisomers could not be estimated exactly; furthermore, extensive overlap of the signals did not allow individual assignments. Since all attempts to separate two isomers by TLC and recrystallization were unsuccessful, the stereochemistry of the isomers has not been determined to date.