Bivalency and epitope specificity of a high-affinity IgG3 monoclonal antibody to the Streptococcus Group A carbohydrate antigen. Molecular modeling of a Fv fragment

Carbohydrate Research

Volumn 324, Issue 1, 2000, Pages 17-29

  Pitner, J Bruce ^a   Beyer, Wayne F ^a   Venetta, Thomas M ^a   Nycz, Colleen ^a   Mitchell, Michael J ^a   Harris, Shannon L ^b   Mariño Albernas, Jose R ^b   Auzanneau, France Isabelle ^b   Forooghian, Farzin ^b   Mario Pinto, B ^b  

^a BD Technologies   (United States)

^b SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Epitope specificity; Group A Streptococcus polysaccharide; Homology modeling; IgG3 monoclonal antibody; Multivalent interactions

Indexed keywords

EPITOPE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G3; MONOCLONAL ANTIBODY;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING SITE; IN VITRO STUDY; MICROCALORIMETRY; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS GROUP A; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, BACTERIAL; BINDING SITES; CALORIMETRY; CARBOHYDRATE SEQUENCE; EPITOPES; IMMUNOASSAY; IMMUNOGLOBULIN FRAGMENTS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POLYSACCHARIDES, BACTERIAL; PROTEIN BINDING; STREPTOCOCCUS PYOGENES; THERMODYNAMICS;

EID: 0033979551     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6215(99)00279-7     Document Type: Article

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