메뉴 건너뛰기




Volumn 57, Issue 2, 2000, Pages 157-164

Extended-release physostigmine in Alzheimer disease: A multicenter, double-blind, 12-week study with dose enrichment

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; PHYSOSTIGMINE SALICYLATE; PLACEBO; SYNAPTON; UNCLASSIFIED DRUG;

EID: 0033979355     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.57.2.157     Document Type: Article
Times cited : (19)

References (34)
  • 1
    • 0028398472 scopus 로고
    • Alzheimer's disease: Pathophysiology and the hope for therapy
    • Brumback RA, Leech RW. Alzheimer's disease: pathophysiology and the hope for therapy. J Okla State Med Assoc. 1994;87:103-111.
    • (1994) J Okla State Med Assoc. , vol.87 , pp. 103-111
    • Brumback, R.A.1    Leech, R.W.2
  • 2
    • 0028109336 scopus 로고
    • The US economic and social costs of Alzheimer's disease revisited
    • Ernst R, Hay J. The US economic and social costs of Alzheimer's disease revisited. Am J Public Health, 1994;84:1261-1264.
    • (1994) Am J Public Health , vol.84 , pp. 1261-1264
    • Ernst, R.1    Hay, J.2
  • 3
    • 0019410162 scopus 로고
    • Alzheimer's disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
    • Whitehouse PJ, Price DL, Clark AW, Coyle JT, DeLong MR. Alzheimer's disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann Neurol. 1981;10:122-126.
    • (1981) Ann Neurol. , vol.10 , pp. 122-126
    • Whitehouse, P.J.1    Price, D.L.2    Clark, A.W.3    Coyle, J.T.4    DeLong, M.R.5
  • 5
    • 0018078940 scopus 로고
    • Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia
    • Perry EK, Tomlinson BE, Blessed G, Bergman K, Gibson PH, Perry RH. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. BMJ. 1978;2:1457-1459.
    • (1978) BMJ , vol.2 , pp. 1457-1459
    • Perry, E.K.1    Tomlinson, B.E.2    Blessed, G.3    Bergman, K.4    Gibson, P.H.5    Perry, R.H.6
  • 6
    • 0024157910 scopus 로고
    • Tetrahydroaminoacridine, 3,4-diaminopyridine and physostigmine: Direct comparison of effects on memory in aged primates
    • Bartus RT, Dean RL, Tetrahydroaminoacridine, 3,4-diaminopyridine and physostigmine: direct comparison of effects on memory in aged primates. Neurobiol Aging. 1988;9:351-356.
    • (1988) Neurobiol Aging , vol.9 , pp. 351-356
    • Bartus, R.T.1    Dean, R.L.2
  • 7
    • 0018256391 scopus 로고
    • Evidence for a direct cholinergic involvement in the scopolamine-induced amnesia in monkeys: Effects of concurrent administration of physostigmine and methylphenidate with scopolamine
    • Bartus RT. Evidence for a direct cholinergic involvement in the scopolamine-induced amnesia in monkeys: effects of concurrent administration of physostigmine and methylphenidate with scopolamine. Pharmacol Biochem Behav. 1978; 9:833-836.
    • (1978) Pharmacol Biochem Behav. , vol.9 , pp. 833-836
    • Bartus, R.T.1
  • 8
    • 0024561304 scopus 로고
    • Chronic oral physostigmme without lecithin improved memory in Alzheimer's disease
    • Thal LJ, Masur DM, Blau AD, Fuld PA, Klauber MR. Chronic oral physostigmme without lecithin improved memory in Alzheimer's disease. J Am Geriatr Soc. 1989; 37:42-48.
    • (1989) J Am Geriatr Soc. , vol.37 , pp. 42-48
    • Thal, L.J.1    Masur, D.M.2    Blau, A.D.3    Fuld, P.A.4    Klauber, M.R.5
  • 10
    • 0023197078 scopus 로고
    • Effects of oral physostigmine in Alzheimer's disease
    • Stern Y, Sano M, Mayeux R. Effects of oral physostigmine in Alzheimer's disease. Ann Neurol. 1987;220:306-310.
    • (1987) Ann Neurol. , vol.220 , pp. 306-310
    • Stern, Y.1    Sano, M.2    Mayeux, R.3
  • 13
    • 0028270519 scopus 로고
    • A 30-week randomized controlled trial of high-dose tacrine in patients with alzheimer's disease
    • Knapp MJ, Knopman DS, Solomon PR, Pendlebury WW, Davis CS, Gracon SI. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994;271:985-991.
    • (1994) JAMA , vol.271 , pp. 985-991
    • Knapp, M.J.1    Knopman, D.S.2    Solomon, P.R.3    Pendlebury, W.W.4    Davis, C.S.5    Gracon, S.I.6
  • 14
    • 0031883716 scopus 로고    scopus 로고
    • A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
    • Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Neurology. 1998;50:136-145.
    • (1998) Neurology , vol.50 , pp. 136-145
    • Rogers, S.L.1    Farlow, M.R.2    Doody, R.S.3    Mohs, R.4    Friedhoff, L.T.5
  • 16
    • 0031902795 scopus 로고    scopus 로고
    • A randomized trial evaluating the efficacy and safety of ENA 713, a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease
    • Corey-Bloom J, Anand R, Veach J. A randomized trial evaluating the efficacy and safety of ENA 713, a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol. 1998;1: 55-65.
    • (1998) Int J Geriatr Psychopharmacol. , vol.1 , pp. 55-65
    • Corey-Bloom, J.1    Anand, R.2    Veach, J.3
  • 19
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. neurology. 1384;34:939-944.
    • (1384) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 20
    • 0016823810 scopus 로고
    • "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Fostein SE, McHugh PR. "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198.
    • (1975) J Psychiatr Res. , vol.12 , pp. 189-198
    • Folstein, M.F.1    Fostein, S.E.2    McHugh, P.R.3
  • 21
    • 0018887732 scopus 로고
    • Pathological verification of ischemic score in differentiation of dementias
    • Rosen WG, Terry RD, Fuld PA, Katzman R, Peck A. Pathological verification of ischemic score in differentiation of dementias. Ann Neurol. 1980;7:486-488.
    • (1980) Ann Neurol. , vol.7 , pp. 486-488
    • Rosen, W.G.1    Terry, R.D.2    Fuld, P.A.3    Katzman, R.4    Peck, A.5
  • 22
    • 0021520020 scopus 로고
    • A new rating scale for Alzheimer's disease
    • Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry. 1984;141:1356-1364.
    • (1984) Am J Psychiatry , vol.141 , pp. 1356-1364
    • Rosen, W.G.1    Mohs, R.C.2    Davis, K.L.3
  • 23
    • 0028114429 scopus 로고
    • The Clinician Interview-Based Impression (CIBI): A clinician's global change rating scale in Alzheimer's disease
    • Knopman DS, Knapp MJ, Gracon SI, Davis CS. The Clinician Interview-Based Impression (CIBI): a clinician's global change rating scale in Alzheimer's disease. Neurology. 1994;44:2315-2321.
    • (1994) Neurology , vol.44 , pp. 2315-2321
    • Knopman, D.S.1    Knapp, M.J.2    Gracon, S.I.3    Davis, C.S.4
  • 24
    • 0000238671 scopus 로고
    • Rockville, Md: Dept of Health, Education and Welfare: Dept of Health, Education and Welfare publication ADM 76-338
    • Clinical Global Impressions. In: Guy W, ed. ECDEU Assessment Manual for Psychopharmacology. Rev ed. Rockville, Md: Dept of Health, Education and Welfare: 1976:218-222. Dept of Health, Education and Welfare publication ADM 76-338.
    • (1976) ECDEU Assessment Manual for Psychopharmacology. Rev Ed. , pp. 218-222
    • Guy, W.1
  • 25
    • 0014579432 scopus 로고
    • Assessment of older people: Self-monitoring and instrumental activities of daily living
    • Lawton MP, Brody EM. Assessment of older people: self-monitoring and instrumental activities of daily living. Gerontologist. 1969;9:179-186.
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 27
    • 0018687930 scopus 로고
    • A multiple testing procedure for clinical trials
    • O'Brien PC, Fleming TR. A multiple testing procedure for clinical trials Biometrics. 1979;35:549-556.
    • (1979) Biometrics , vol.35 , pp. 549-556
    • O'Brien, P.C.1    Fleming, T.R.2
  • 28
    • 70449529019 scopus 로고
    • Discrete sequential boundaries for clinical trials
    • Lan KKG, DeMets DL. Discrete sequential boundaries for clinical trials. Biometrika. 1983;70:659-664.
    • (1983) Biometrika , vol.70 , pp. 659-664
    • Lan, K.K.G.1    DeMets, D.L.2
  • 30
    • 0032921029 scopus 로고    scopus 로고
    • A 24-week randomized trial of controlled-release physostigrnine in patients with Alzheimer's disease
    • Thal LJ, Ferguson JM, Mintzer J, Raskin A, Targum SD. A 24-week randomized trial of controlled-release physostigrnine in patients with Alzheimer's disease. Neurology. 1999;52:1146-1152.
    • (1999) Neurology , vol.52 , pp. 1146-1152
    • Thal, L.J.1    Ferguson, J.M.2    Mintzer, J.3    Raskin, A.4    Targum, S.D.5
  • 31
    • 10244259208 scopus 로고    scopus 로고
    • The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicenter, randomized, double-blind, placebo-controlled trial
    • Rogers SL, Friedhoff LT, and the Donepezil Study Group The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicenter, randomized, double-blind, placebo-controlled trial. Dementia. 1996;7:293-303.
    • (1996) Dementia , vol.7 , pp. 293-303
    • Rogers, S.L.1    Friedhoff, L.T.2
  • 32
    • 0031842293 scopus 로고    scopus 로고
    • Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease
    • Morris JC, Cyrus PA, Orazem J, Mas J, Bieber F, Ruzicka BB, Gulanski B. Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease. neurology. 1998;50:1222-1230.
    • (1998) Neurology , vol.50 , pp. 1222-1230
    • Morris, J.C.1    Cyrus, P.A.2    Orazem, J.3    Mas, J.4    Bieber, F.5    Ruzicka, B.B.6    Gulanski, B.7
  • 33
    • 0029143531 scopus 로고
    • Effectiveness and safety of velnacrine for the treatment of Alzheimer's disease
    • Antuono PG. Effectiveness and safety of velnacrine for the treatment of Alzheimer's disease. Arch Intern Med. 1995;155:1766-1772.
    • (1995) Arch Intern Med. , vol.155 , pp. 1766-1772
    • Antuono, P.G.1
  • 34
    • 0024346285 scopus 로고
    • Measurement of quality-of-life changes in patients with Alzheimer's disease
    • DeJong R, Osterlund OW, Roy GW. Measurement of quality-of-life changes in patients with Alzheimer's disease. Clin Ther. 1989;11:545-554.
    • (1989) Clin Ther. , vol.11 , pp. 545-554
    • DeJong, R.1    Osterlund, O.W.2    Roy, G.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.