Cytokine expression and production by purified Helicobacter pylori urease in human gastric epithelial cells

Infection and Immunity

Volumn 68, Issue 2, 2000, Pages 664-671

  Tanahashi, Toshihito ^a   Kita, Masakazu ^a   Kodama, Tadashi ^a   Yamaoka, Yoshio ^a   Sawai, Naoki ^a   Ohno, Tomoyuki ^a   Mitsufuji, Shoji ^a   Wei, Ya Ping ^a   Kashima, Kei ^a   Imanishi, Jiro ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA; UREASE;

ARTICLE; BACTERIAL VIRULENCE; CANCER CELL CULTURE; CELL CULTURE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; MONONUCLEAR CELL; MUCOSA INFLAMMATION; MUCOSAL IMMUNITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH EPITHELIUM;

ADULT; CELL LINE; CYTOKINES; GASTRIC MUCOSA; HELICOBACTER PYLORI; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; RNA, MESSENGER; UREASE;

EID: 0033978768     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.2.664-671.2000     Document Type: Article

References (30)

1. Aihara, M., K. Imagawa, Y. Funakoshi, Y. Ohmoto, and M. Kikuchi. 1998. Effects of rebamipide on production of several cytokines by human peripheral blood mononuclear cells. Dig. Dis. Sci. 43:160S-166S.
2. Akira, S., T. Hirano, and T. Taga. 1990. Biology of multifocal cytokines: IL6 and related molecules (IL1 and TNF). FASEB J. 4:2860-2867.
3. Ando, T., K. Kusugami, M. Ohsuga, K. Ina, M. Shinoda, T. Konagaya, T. Sakai, A. Imada, N. Kasuga, T. Nada, S. Ichiyama, and M. J. Blaser. 1998. Differential normalization of mucosal interleukin-8 and interleukin-6 activity after Helicobacter pylori eradication. Infect. Immun. 66:4742-4747.
4. Baggiolini, M., A. Walz, and S. L. Kunkel. 1989. Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J. Clin. Investig. 84:1045-1049.
5. Censini, S., C. Lange, Z. Xiang, J. E. Crabtree, P. Ghiara, M. Borodovsky, R. Rappuoli, and A. Covacci. 1996. cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc. Natl. Acad. Sci. USA 93:14648-14653.
6. Crabtree, J. E., J. I. Wyatt, L. K. Trejdosiewicz, P. Peichl, P. H. Nichols, N. Ramsay, J. N. Primrose, and I. J. Lindley. 1994. Interleukin-8 expression in Helicobacter pylori infected, normal, and neoplastic gastroduodenal mucosa. J. Clin. Pathol. 47:61-66.
7. Crabtree, J. E., Z. Xiang, I. J. Lindley, D. S. Tompkins, R. Rappuoli, and A. Covacci. 1995. Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori. J. Clin. Pathol. 48:967-969.
8. + T-cell clones from peripheral blood and gastric biopsies. Infect. Immun. 63:1102-1106.
9. Evans, D. J., D. G. Evans, S. S. Kirkpatrick, and D. Y. Graham. 1991. Characterization of the Helicobacter pylori urease and purification of its subunits. Microb. Pathog. 10:15-26.
10. Goodman, R. E., F. Nestle, Y. M. Naidu, J. M. Green, C. B. Thompson, B. J. Nickoloff, and L. A. Turka. 1994. Keratinocyte-derived T cell costimulation induces preferential production of IL-2 and IL-4 but not IFN-gamma. J. Immunol. 152:5189-5198.
11. Harris, P. R., P. B. Ernst, S. Kawabata, H. Kiyono, M. F. Graham, and P. D. Smith. 1998. Recombinant Helicobacter pylori urease activates primary mucosal macrophages. J. Infect. Dis. 178:1516-1520.
12. Harris, P. R., H. L. Mobley, P. G. Perez, M. J. Blaser, and P. D. Smith. 1996. Helicobacter pylori urease is a potent stimulus of mononuclear phagocyte activation and inflammatory cytokine production. Gastroenterology 111:419-425.
13. Huang, J., P. W. O'Toole, P. Doig, and T. J. Trust. 1995. Stimulation of interleukin-8 production in epithelial cell lines by Helicobacter pylori. Infect. Immun. 63:1732-1738.
14. Karttunen, R. A., T. J. Karttunen, M. M. Yousfi, H. M. el-Zimaity, D. Y. Graham, and F. A. el-Zaatari. 1997. Expression of mRNA for interferon-gamma, interleukin-10, and interleukin-12 (p40) in normal gastric mucosa and in mucosa infected with Helicobacter pylori. Scand. J. Gastroenterol. 32:22-27.
15. Levi, S., K. Beardshall, G. Haddad, R. Playford, P. Ghosh, and J. Calam. 1989. Campylobacter pylori and duodenal ulcers: the gastrin link. Lancet i:1167-1168.
16. Lindholm, C., M. Quiding-Järbrink, H. Lönroth, A. Hamlet, and A.-M. Svennerholm. 1998. Local cytokine response in Helicobacter pylori-infected subjects. Infect. Immun. 66:5964-5971.
17. Moss, S. F., S. Legon, J. Davies, and J. Calam. 1994. Cytokine gene expression in Helicobacter pylori associated antral gastritis. Gut 35:1567-1570.
18. National Institutes of Health Consensus Conference. 1994. Helicobacter pylori in peptic ulcer disease. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease. JAMA 272:65-69.
19. Noach, L. A., N. B. Bosma, J. Jansen, F. J. Hoek, S. J. van Deventer, and G. N. Tytgat. 1994. Mucosal tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8 production in patients with Helicobacter pylori infection. Scand. J. Gastroenterol. 29:425-429.
20. Phadnis, S. H., M. H. Parlow, M. Levy, D. Ilver, C. M. Caulkins, J. B. Connors, and B. E. Dunn. 1996. Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis. Infect. Immun. 64:905-912.
21. Rieder, G., R. A. Hatz, A. P. Moran, A. Walz, M. Stolte, and G. Enders. 1997. Role of adherence in interleukin-8 induction in Helicobacter pylori-associated gastritis. Infect. Immun. 65:3622-3630.
22. Sharma, S. A., M. K. Tummuru, M. J. Blaser, and L. D. Kerr. 1998. Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappaB in gastric epithelial cells. J. Immunol. 160:2401-2407.
23. Sharma, S. A., M. K. Tummuru, G. G. Miller, and M. J. Blaser. 1995. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro. Infect. Immun. 63:1681-1687.
24. Smoot, D. T., J. H. Resau, T. Naab, B. C. Desbordes, T. Gilliam, H. K. Bull, S. B. Curry, J. Nidiry, J. Sewchand, and R. K. Mills. 1993. Adherence of Helicobacter pylori to cultured human gastric epithelial cells. Infect. Immun. 61:350-355.
25. Takahashi, M., K. Ogura, S. Maeda, K. Mori, K. Mafune, Y. Mikami, A. Terano, and M. Omata. 1997. Promoters of epithelialization induce expression of vascular endothelial growth factor in human gastric epithelial cells in primary culture. FEBS Lett. 418:115-118.
26. Tummuru, M. K., S. A. Sharma, and M. J. Blaser. 1995. Helicobacter pylori picB, a homologue of the Bordetella pertussis toxin secretion protein, is required for induction of IL-8 in gastric epithelial cells. Mol. Microbiol. 18:867-876.
27. Ushio, S., M. Namba, T. Okura, K. Hattori, Y. Nukada, K. Akita, F. Tanabe, K. Konishi, M. Micallef, M. Fujii, K. Torigoe, T. Tanimoto, S. Fukuda, M. Ikeda, H. Okamura, and M. Kurimoto. 1996. Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J. Immunol. 156:4274-4279.
28. Weigert, N., K. Schaffer, V. Schusdziarra, M. Classen, and W. Schepp. 1996. Gastrin secretion from primary cultures of rabbit antral G cells: stimulation by inflammatory cytokines. Gastroenterology 110:147-154.
29. Yamaoka, Y., M. Kita, T. Kodama, N. Sawai, and J. Imanishi. 1996. Helicobacter pylori cagA gene and expression of cytokine messenger RNA in gastric mucosa. Gastroenterology 110:1744-1752.
30. Yamaoka, Y., M. Kita, T. Kodama, N. Sawai, K. Kashima, and J. Imanishi. 1997. Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains. Gut 41:442-451.