Spermine dependent activation of the N-methyl-D-aspartate receptor and the effect of nitric oxide synthase inhibition during hypoxia in the cerebral cortex of newborn piglets

Brain Research

Volumn 854, Issue 1-2, 2000, Pages 11-18

  Zubrow, Alan B ^a   Numagami, Yoshihiro ^a   Fritz, Karen I ^a   Mishra, Om P ^a   Delivoria Papadopoulos, Maria ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Hypoxia; MK 801 receptor ion channel complex; Newborn; Nitric oxide synthase; Spermine

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE; SPERMINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; ENZYME INHIBITION; HYPOXIA; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; SWINE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; ANOXIA; CEREBRAL CORTEX; DIZOCILPINE MALEATE; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; NITRIC OXIDE SYNTHASE; NITROARGININE; RECEPTORS, N-METHYL-D-ASPARTATE; REFERENCE VALUES; SPERMINE; SWINE;

EID: 0033978295     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02252-0     Document Type: Article

References (66)

1. Balazs R., Hack N., Jorgensen O.S. Stimulation of the N-methyl-D-aspartate receptor has a trophic effect of differentiating cerebellar granule cells. Neurosci. Lett. 87:1988;80-86.
2. Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freeman B.A. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U.S.A. 87:1990;1620-1624.
3. Benveniste H., Drejer J., Schousboe A., Diemer N.H. Evaluation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43:1984;1369-1374.
4. Benveniste M., Mayer M.L. Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurons. J. Physiol. (London). 464:1993;131-163.
5. Bourdiol F., Fage D., Serrano A., Carter C., Benavides J., Scatton B. Neurotoxic effects of the intrastriatal injection of spermine and spermidine: lack of involvement of NMDA receptors. Brain Res. 596:1992;183-188.
6. Bueb J.L., Mousli M., Landry Y. Molecular basis for cellular effects of naturally occurring polyamines. Agents Actions. 33:1991;84-86.
7. Carter C., Lloyd K.G., Zivkovic B., Scatton B. Ifenprodil and SL 82.0715 as cerebral antiischemic agents: III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex. J. Pharmacol. Exp. Ther. 253:1990;475-482.
8. Collingridge G.L., Lester R.A. Excitatory amino acid receptors in the vertebrate central nervous system. Pharmacol. Rev. 41:1989;143-210.
9. Dawson V.L., Dawson T.M., London E.D., Bredt D.S., Snyder S.H. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc. Natl. Acad. Sci. U.S.A. 88:1991;6368-6371.
10. de Vera N., Artigas F., Serratosa J., Martinez E. Changes in polyamine levels in rat brain after systemic kainic acid administration: relationship to convulsant activity and brain damage. J. Neurochem. 57:1991;1-8.
11. Delivoria-Papadopoulos M., Mishra O.P. Mechanisms of cerebral injury in perinatal asphyxia and strategies for prevention. J. Pediatr. 132:1998;S30-S34.
12. Fage D., Carboni S., Voltz C., Scatton B., Carter C. Ornithine decarboxylase inhibition of NMDA receptor antagonism reduces cortical polyamine efflux associated with dialysis probe implantation. Neurosci. Lett. 149:1993;173-176.
13. Fage D., Voltz C., Scatton B., Carter C. Selective release of spermine and spermidine from the rat striatum by N-methyl-D-aspartate receptor activation in vivo. J. Neurochem. 58:1992;2170-2175.
14. Fahey J.M., Pritchard G.A., Miller L.G. Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons. Neurosci Lett. 161:1993;109-112.
15. Frandsen A., Schousboe A. Excitatory amino acid-mediated cytotoxicity and calcium homeostasis in cultured neurons. J. Neurochem. 60:1993;1202-1211.
16. Fritz K.I., Groenendaal F., McGowan J.E., Mishra O.P., Delivoria-Papadopoulos M. Effect of cerebral hypoxia on NMDA receptor binding characteristics after treatment with 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP) in newborn piglets. Brain Res. 729:1996;66-74.
17. Garthwaite J., Garthwaite G., Palmer R.M., Moncada S. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slice. Eur. J. Pharmacol. 172:1989;413-416.
18. Globus M.Y., Busto R., Dietrich W.D., Martinez E., Valdes I., Ginsberg M.D. Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis. J. Neurochem. 51:1988;1455-1464.
19. Goel R., Mishra O.P., Razdan B., Delivoria-Papadopoulos M. Modification of NMDA receptor by in vitro lipid peroxidation in fetal guinea pig brain. Neurosci. Lett. 151:1993;219-223.
20. +-ATPase activity after inhibition of cerebral nitric oxide synthase by intravenous N-nitro-L-arginine in newborn piglets. Biol. Neonate. 68:1995;419-425.
21. Halliwell B. Reactive oxygen species and the central nervous system. J. Neurochem. 59:1992;1609-1623.
22. Hamada Y., Hayakawa T., Hattori H., Mikawa H. Inhibitor of nitric oxide synthesis reduced hypoxia-ischemic brain damage in the neonatal rat. Ped. Res. 35:1994;10-14.
23. Harik S.I., Doull G.H., Dick A.P. Specific ouabain binding to brain microvessels and choroid plexus. J. Cereb. Blood Flow Metab. 5:1985;156-160.
24. Harman R.J., Shaw G.G. The spontaneous and evoked release of spermine from rat brain in vitro. Br. J. Pharmacol. 73:1981;165-174.
25. Hoffman D.J., McGowan J.E., Marro P.J., Mishra O.P., Delivoria-Papadopoulos M. Hypoxia induced modification of the N-methyl-D-aspartate receptor in the brain of the newborn piglet. Neurosci. Lett. 167:1994;156-160.
26. Kashiwagi K., Fukuchi J., Chao J., Igareshi K., Williams K. An aspartate residue in the extracellular loop of the N-methyl-D-aspartate receptor controls sensitivity to spermine and protons. Mol. Pharmacol. 49:1996;1131-1141.
27. Koenig H., Goldstone A.D., Lu C.J., Trout J.J. Brain polyamines are controlled by N-methyl-D-aspartate receptors during ischemia and recirculation. Stroke. 21(III):1990;98-102.
28. Kuppusamy P., Ohnishi S.T., Numagami Y., Ohnishi T., Zweier J.L. Three-dimensional imaging of nitric oxide production in the rat brain subjected to ischemia-hypoxia. J. Cereb. Blood Flow Metab. 15:1995;899-903.
29. Lafon-Cazal M., Pietri S., Culcasi M., Bockaert J. NMDA-dependent superoxide production and neurotoxicity. Nature. 364:1993;535-537.
30. W. Lamprecht, P. Stein, F. Heinz, H. Weissner, Creative phosphate, in: H.U. Bergmeyer (Ed.), Methods of Enzymatic Analysis, Academic Press, Vol. 4, New York, 1974, pp. 1777-1781.
31. Lerma J. Spermine regulates N-methyl-D-aspartate receptor desensitization. Neuron. 8:1992;343-352.
32. Lipton S.A., Rosenberg P.A. Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med. 330:1994;613-622.
33. London E.D., Muklin A. Polyamines as endogenous modulators of the N-methyl-D-aspartate receptor. Ann. N.Y. Acad. Sci. 757:1995;430-436.
34. Lowry O., Rosenbrough N.J., Farr A., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
35. Malinski T., Bailey F., Zhang Z.G., Chopp M. Nitric oxide measured by a porphrynic microsensor in rat brain after transient middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 12:1993;355-358.
36. McDonald J.W., Johnston M.V. Excitatory amino acid neurotoxicity in the developing brain. NIDA Res. Monogr. Ser. 133:1993;185-205.
37. McDonald J.W., Johnston M.V. Physiological and pathophysiological roles of excitatory amino acids during central nervous system development. Brain Res. Rev. 15:1990;41-70.
38. McGurk J.F., Bennett M.V.L., Zukin R.S. Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in xenopus oocytes. Proc. Natl. Acad. Sci. U.S.A. 87:1990;9971-9974.
39. Mishra O.P., Delivoria-Papadopoulos M. Cellular mechanisms of hypoxic injury in the developing brain. Brain Res. Bull. 48:1999;233-238.
40. Mishra O.P., Kubin J.A., McGowan J.E., Delivoria-Papadopoulos M. Kainate receptor modification in the fetal guinea pig brain during hypoxia. Neurochem. Res. 20:1995;1171-1177.
41. Mishra O.P., Delivoria-Papadopoulos M. NMDA receptor modification in the fetal guinea pig brain during hypoxia. Neurochem. Res. 17:1992;1211-1216.
42. Nowicki J.P., Duval D., Poignet H., Scalton B. Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse. Eur. J. Pharmacol. 204:1991;339-340.
43. Numagami Y., Zubrow A.B., Mishra O.P., Delivoria-Papadopoulos M. Lipid free radical generation and brain cell membrane alteration following nitric oxide synthase inhibition during cerebral hypoxia in the newborn piglet. J. Neurochem. 69:1997;1542-1547.
44. Paschen W., Widmann R., Weber C. Changes in regional polyamine profiles in rat brains after cerebral ischemia (single versus repetitive ischemia): evidence for release of polyamines from injured neurons. Neurosci. Lett. 135:1992;121-124.
45. Paschen W., Schmidt-Kastner R., Djuricic B., Meese C., Linn F., Hossmann K.A. Polyamine changes in reversible cerebral ischemia. J. Neurochem. 49:1987;35-37.
46. Paschen W. Polyamine metabolism in different pathological states of the brain. Mol. Chem. Neuropathol. 16:1992;241-271.
47. Paschen W., Hallmayer J., Rohn G. Relationship between putrescine content and density of ischemic cell damage in the brain of mongolian gerbils: effect of nimodipine and barbiturate. Acta Neuropathol. 76:1988;388-394.
48. Radi R., Beckman J.S., Bush K.M., Freeman B.A. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288:1991;481-487.
49. Read G.W., Hong S.M., Kiefer F F. Competitive inhibition of 48/80-induced histamine release by benzalkonium chloride and its analogs and the polyamine receptor in mast cells. J. Pharmacol. Exp. Ther. 222:1982;652-657.
50. Reynolds I.J. 1,5-(Diethylamino)piperdine, a novel spermidine analogue that more specifically activates the N-methyl-D-aspartate receptor-associated polyamine site. Mol. Pharmacol. 41:1992;989-992.
51. Reynolds J., Miller R.J. Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines. Mol. Pharmacol. 36:1989;758-765.
52. Rock D.M., MacDonald R.L. The polyamine spermine has multiple actions on N-methyl-D-aspartate receptor single-channel currents in cultured cortical neurons. Mol. Pharmacol. 41:1992;83-88.
53. Rock D.M., MacDonald R.L. Spermine and related polyamines produce a voltage-dependent reduction of N-methyl-D-aspartate receptor single channel conductance. Mol. Pharmacol. 42:1992;157-164.
54. Sacaan A.I., Johnson K.M. Spermine enhances binding to the glycine site associated with the N-methyl-D-aspartate complex. Mol. Pharmacol. 36:1989;836-839.
55. Seiler N. Polyamine metabolism and function in brain. Neurochem. Int. 3:1981;95-110.
56. Seiler N., Degeure F. Polyamine transport in mammalian cells. Int. J. Biochem. 22:1990;211-218.
57. Shaw G.G., Pateman A.J. The regional distribution of polyamines spermidine and spermine in brain. J. Neurochem. 20:1973;1225-1230.
58. Snyder S.H. Nitric oxide: first in a new class of neurotransmitters. Science. 257:1992;494-496.
59. Sprosen T.S., Woodryff G.N. Polyamines potentiate NMDA induced whole-cell currents in cultured striatal neurons. Eur. J. Pharmacol. 179:1990;477-478.
60. Tominaga T., Sato S., Ohnishi T., Ohnishi S.T. Electron paramagnetic resonance detection of nitric oxide produced during forebrain ischemia of the rat. J. Cereb. Blood Flow Metab. 14:1994;715-722.
61. 3H ]MK801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site Mol. Pharmacol. 36:1989;575-581.
62. Williams K. Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors. Mol. Pharmacol. 46:1994;161-168.
63. Williams K., Zappin A.M., Pritchett D.B., Shen Y.M., Molinoff P.B. Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 submits. Mol. Pharmacol. 45:1994;803-809.
64. Yeagle P. Lipid regulation of cell membrane structure and function. FASEB J. 3:1989;1833-1842.
65. Zanelli S.A., Numagami Y., McGowan J.E., Mishra O.P., Delivoria-Papadopoulos M. NMDA receptor-mediated calcium influx in cerebral cortical synaptosomes of the hypoxic guinea pig fetus. Neurochem. Res. 24:1999;437-446.
66. 2+ potentiation of recombinant NMDA receptors. Neuron. 12:1994;811-818.