Modification of Cys-418 of pyruvate formate-lyase by methacrylic acid, based on its radical mechanism

FEBS Letters

Volumn 466, Issue 1, 2000, Pages 45-48

  Plaga, Wulf ^a   Vielhaber, Gabriele ^a   Wallach, Jochen ^a   Knappe, Joachim ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

1 14C Methacrylic acid; Enzyme inactivation; Pyruvate formate lyase; Radical enzyme; S (2 Carboxy (2S) propyl) L cysteine

Indexed keywords

FORMATE ACETYLTRANSFERASE; LYASE; METHACRYLIC ACID; RADICAL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CRYSTAL STRUCTURE; ENZYME INACTIVATION; ENZYME STRUCTURE; ENZYME SYNTHESIS; ESCHERICHIA COLI; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; RACEMIC MIXTURE; REACTION ANALYSIS; STEREOCHEMISTRY;

ACETYLTRANSFERASES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CYSTEINE; ENZYME INHIBITORS; ESCHERICHIA COLI; FREE RADICALS; KINETICS; METHACRYLATES; MODELS, CHEMICAL; PEPTIDE MAPPING; RECOMBINANT PROTEINS;

EID: 0033978229     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01752-4     Document Type: Article

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