Validation of immune-complex enzyme immunoassays for diagnosis of pneumococcal pneumonia among adults in Kenya

Clinical and Diagnostic Laboratory Immunology

Volumn 7, Issue 1, 2000, Pages 64-67

  Scott, J A G ^a,b   Hall, A J ^b   Leinonen, M ^c  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

PNEUMOCOCCUS VACCINE; PNEUMOLYSIN; POLYSACCHARIDE;

ADULT; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BLOOD CULTURE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DRUG EFFICACY; ENZYME IMMUNOASSAY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KENYA; LOBAR PNEUMONIA; MAJOR CLINICAL STUDY; MALE; OPTICAL DENSITY; PRIORITY JOURNAL;

EID: 0033978192     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/cdli.7.1.64-67.2000     Document Type: Article

References (20)

1. Claesson, B. A., B. Trollfors, I. Brolin, M. Granstrom, J. Henrichsen, U. Jodal, P. Juto, I. Kallings, K. Kanclerski, T. Lagergard, L. Steinwall, and O. Strannegard. 1989. Etiology of community-acquired pneumonia in children based on antibody responses to bacterial and viral antigens. Pediatr. Infect. Dis. J. 8:856-862.
2. Dagan, R., O. Shriker, I. Hazan, E. Leibovitz, D. Greenberg, F. Schlaeffer, and R. Levy. 1998. Prospective study to determine clinical relevance of detection of pneumococcal DNA in sera of children by PCR. J. Clin. Microbiol. 36:669-673.
3. Griffiths, E., P. Stevenson, R. Thorpe, and H. Chart. 1985. Naturally occurring antibodies in human sera that react with the iron-regulated outer membrane proteins of Escherichia coli. Infect. Immun. 47:808-813.
4. Jalonen, E., S. Taira, J. C. Paton, Y. Kerttula, P. Suomalainen, and M. Leinonen. 1990. Pneumolysin produced by Bacillus subtilis as antigen for measurement of pneumococcal antibodies by enzyme immunoassay. Serodiagn. Immunother. Infect. Dis. 4:459-468.
5. Kanclerski, K., S. Blomquist, M. Granstrom, and R. Mollby. 1988. Serum antibodies to pneumolysin in patients with pneumonia. J. Clin. Microbiol. 26:96-100.
6. Kanclerski, K., M. Granstrom, and R. Mollby. 1987. Immunological relation between serum antibodies against pneumolysin and against streptolysin O. Acta Pathol. Microbiol. Immunol. Scand. Sect. B 95:241-244.
7. Kauppinen, M. T., E. Herva, P. Kujala, M. Leinonen, P. Saikku, and H. Syrjala. 1995. The etiology of community-acquired pneumonia among hospitalized patients during a Chlamydiapneumoniae epidemic in Finland. J. Infect. Dis. 172:1330-1335.
8. Koivula, I., M. Sten, M. Leinonen, and P. H. Makela. 1997. Clinical efficacy of pneumococcal vaccine in the elderly: a randomized, single-blind population-based trial. Am. J. Med. 103:281-290.
9. Korppi, M., K. T. Heiskanen, E. Jalonen, P. Saikku, M. Leinonen, P. Halonen, and P. H. Makela. 1993. Aetiology of community-acquired pneumonia in children treated in hospital. Eur. J. Pediatr. 152:24-30.
10. Korppi, M., M. Koskela, E. Jalonen, and M. Leinonen. 1992. Serologically indicated pneumococcal respiratory infection in children. Scand. J. Infect. Dis. 24:437-443.
11. Korppi, M., and M. Leinonen. 1997. Pneumococcal pneumonia in children; new data from circulating immune complexes. Eur. J. Pediatr. 156:341-342.
12. Leinonen, M., H. Syrjälä, E. Jalonen, P. Kujala, and E. Herva. 1990. Demonstration of pneumolysin antibodies in circulating immune complexes - a new diagnostic method for pneumococcal pneumonia. Serodiagn. Immunother. Infect. Dis. 4:451-458.
13. Lieberman, D., K. Schlaefler, I. Boldur, D. Lieberman, S. Horowitz, M. G. Friedman, M. Leinonen, O. Horovitz, E. Manor, and A. Porath. 1996. Multiple pathogens in adult patients admitted with community-acquired pneumonia: a one year prospective study of 346 consecutive patients. Thorax 51:179-184.
14. Ortqvist, A., J. Hedlund, L.-A. Burman, E. Elbel, M. Hofer, M. Leinonen, I. Lindblad, B. Sundelof, M. Kalin, and the Swedish Pneumococcal Vaccine Study Group. 1998. Randomised trial of 23-valent pneumococcal capsular polysaccharide vaccine in prevention of pneumonia in middle-aged and elderly people. Lancet 351:399-403.
15. Paton, J. C., R. A. Lock, and D. J. Hansman. 1986. Cloning and expression in Escherichia coli of the Streptococcus pneumoniae gene encoding pneumolysin. Infect. Immun. 54:50-55.
16. Rodriguez Barradas, M. C., D. M. Musher, R. J. Hamill, M. Dowell, J. T. Bagwell, and C. V. Sanders. 1992. Unusual manifestations of pneumococcal infection in human immunodeficiency virus-infected individuals: the past revisited. Clin. Infect. Dis. 14:192-199.
17. Scott, J. A. G., A. Hannington, K. Marsh, and A. J. Hall. 1999. Diagnosis of pneumococcal pneumonia in epidemioiogical studies: evaluation in Kenyan adults of a serotype-specific urine latex agglutination assay. Clin. Infect. Dis. 28:764-769.
18. Sutliff, W. D., and A. Zoffuto. 1968. Pneumolysin and antipneumolysin. Antimicrob. Agents Chemother. 8:350-352.
19. Taira, S., E. Jalonen, J. C. Paton, M. Sarvas, and K. Runeberg-Nyman. 1989. Production of pneumolysin, a pneumococcal protein toxin, in Bacillus subtilis. Gene 77:211-218.
20. Tweten, R. K. 1988. Nucleotide sequence of the gene for perfringolysin O (theta-toxin) from Clostridium perfringens: significant homology with the genes for streptolysin O and pneumolysin. Infect. Immun, 56:3235-3240.