Retrograde tracing and neuropeptide immunohistochemistry of sensory neurones protecting to the cartilaginous distal femoral epiphysis of young rats

Cell and Tissue Research

Volumn 299, Issue 2, 2000, Pages 193-200

  Edoff, Karin ^a   Grenegård, Magnus ^a   Hildebrand, Claes ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Calcitonin gene related peptide; cAMP; Dorsal root ganglion; Fast blue; Hyaline cartilage; Rat (Sprague Dawley); Substance P

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CYCLIC AMP; FAST BLUE; NEUROPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE; FEMALE; FEMUR EPIPHYSIS; IMMUNOHISTOCHEMISTRY; INNERVATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SECOND MESSENGER; SENSORY NERVE CELL; SPINAL GANGLION;

AMIDINES; ANIMALS; AXONAL TRANSPORT; CALCITONIN GENE-RELATED PEPTIDE; CARTILAGE, ARTICULAR; COLORING AGENTS; CYCLIC AMP; EPIPHYSES; FEMALE; FEMUR; GANGLIA, SPINAL; MALE; NERVE TISSUE PROTEINS; NEURONS, AFFERENT; ORGAN CULTURE TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SECOND MESSENGER SYSTEMS; SUBSTANCE P;

ANIMALIA;

EID: 0033977037     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410050017     Document Type: Article

References (67)

1. Axelsson KL, Bornefeldt KE, Norlander B, Wikberg JE (1988) Attomole sensitive radioimmunoassay for cyclic GMP. Sec Mess Phosphoprot 12:145-154
2. Baron R, Jänig W, Kollmann W (1988) Sympathetic and afferent somata projecting in hindlimb nerves and the anatomical organization of the lumbar sympathetic nervous system of the rat. J Comp Neurol 275:460-468
3. Bernard GW, Shih C (1990) The osteogenic stimulating effect of neuroactive calcitonin gene-related peptide. Peptides 11:625-632
4. Bidegain M, Roos BA, Hill EL, Howard GA, Balkan W (1995) Calcitonin gene-related peptide (CGRP) in the developing mouse limb. Endocr Res 21:743-755
5. Bjurholm A (1991) Neuroendocrine peptides in bone. Int Orthop 15:325-329
6. Bjurholm A, Kreicbergs A, Schultzberg M, Lerner UH (1992) Neuroendocrine regulation of cyclic AMP formation in three different osteoblastic cell lines (UMR 106-01, ROS 17/2.8, and Saos-2). J Bone Miner Res 7:1011-1019
7. Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
8. Brain SD, Cambridge H (1996) Calcitonin gene-related peptide: vasoactive effects and potential therapeutic role. Gen Pharmacol 27:607-611
9. Brain SD, Williams TJ, Tippins JR, Morris HR, MacIntyre I (1985) Calcitonin gene-related peptide is a potent vasodilator. Nature 313:54-56
10. Dalsgaard C-J, Hultgårdh-Nilsson A, Haegerstrand A, Nilsson J (1989) Neuropeptides as growth factors. Possible roles in human diseases. Regul Pept 25:1-9
11. Dietz FR (1989) Effect of denervation on limb growth. J Orthop Res 7:292-303
12. Diez Guerra FJ, Zadi M, Bevis P, MacIntyre I, Emson PC (1988) Evidence for release of calcitonin gene-related peptide and neurokinin A from sensory nerve endings in vivo. Neuroscience 25:839-846
13. Doughty SE, Atkinson ME, Shehab SA (1991) A quantitative study of neuropeptide immunoreactive cell bodies of primary afferent sensory neurones following rat sciatic nerve peripheral axotomy. Regul Pept 35:59-72
14. Edoff K, Hildebrand C (1998) Sensory neurones containing calcitonin gene-related peptide project to growing cartilage in the young rat. Eur J Neurosci 10:444
15. Edoff K, Hellman J, Persliden J, Hildebrand C (1997) The developmental skeletal growth in the rat foot is reduced after denervation. Anat Embryol 195:531-538
16. Gozes I, Brenneman DE (1993) Neuropeptides as growth and differentiation factors in general and VIP in particular. J Mol Neurosci 4:1-9
17. Gressens P, Hill JM, Gozes I, Fridkin M, Brenneman D E (1993) Growth factor function of vasoactive intestinal polypeptide in whole cultured mouse embryos. Nature 362:155-158
18. Haegerstrand A, Dalsgaard CJ, Jonzon B, Larsson O, Nilsson J (1990) Calcitonin gene-related peptide stimulates proliferation of human endothelial cells. Proc Natl Acad Sci USA 87:3299-3303
19. Hanesch U, Heppelmann B (1995) A simple method for a specific retrograde labelling of dorsal root and sympathetic ganglion cells innervating the knee joint of the cat. J Neurosci Methods 63:55-59
20. Hanesch U, Schaible H-G (1995) Effects of ankle joint inflamation on the proportion of calcitonin gene-related peptide (CGRP)-immunopositive perikarya in dorsal root ganglia. Prog Brain Res 104:339-347
21. Hanesch U, Heppelmann B, Schmidt RF (1997) Quantification of cat's articular afferents containing calcitonin gene-related peptide or substance P innervating normal and acutely inflamed knee joints. Neurosci Lett 233:105-108
22. Hara-Irie F, Amizuka N, Ozawa H (1996) Immunohistochemical and ultrastructural localization of CGRP-positive nerve fibres at the epiphyseal trabecules facing the growth plate of rat femurs. Bone 18:29-39
23. Hedberg A, Messner C, Persliden J, Hildebrand C (1995) Transient local presence of nerve fibers at onset of secondary ossification in the rat knee joint. Anat Embryol 192:247-255
24. Hill EL, Elde R (1988) Calcitonin gene-related peptide-immunoreactive nerve fibres in mandibular periosteum of rat: evidence for primary afferent origin. Neurosci Lett 85:172-178
25. Hill EL, Elde R (1991) Distribution of CGRP-, VIP-, D beta H-, SP-, and NPY-immunoreactive nerves in the periosteum of the rat. Cell Tissue Res 264:469-480
26. Hukkanen M, Konttinen YT, Rees RG, Santavirta S, Terenghi G, Polak J (1992) Distribution of nerve endings and sensory neuropeptide in rat synovium, meniscus and bone. Int J Tissue React 19:1-10
27. Hu-Tsai M, Winter J, Woolf CJ (1992) Regional differences in the distribution of capsaicin-sensitive target-identified adult rat dorsal root ganglion neurons. Neurosci Lett 143:251-254
28. Ishida-Yamamoto A, Tohyama M (1989) Calcitonin gene-related peptide in the nervous tissue. Prog Neurobiol 33:335-386
29. Jancsó G (1992) Pathobiological reactions of C-fibre primary sensory neurones to peripheral nerve injury. Exp Physiol 77:405-431
30. Jenq CB, Chung K, Coggeshall RE (1986) Postnatal loss of axons in normal rat sciatic nerve. J Comp Neurol 244:445-450
31. Johansson O, Madsen K (1987) Stimulative effect of somatostatin on cell proliferation in cultured chondrocytes. Med Biol 65: 57-60
32. Ju G, Hökfelt T, Brodin E, Fahrenkrug J, Fischer JA, Frey P, Elde RP, Brown JC (1987) Primary sensory neurons of the rat showing calcitonin gene-related peptide immunoreactivity and their relation to substance P-, somatostatin-, galanin-, vasoac-tive intestinal polypeptide-and cholecystokinin-immunoreactive ganglion cells. Cell Tissue Res 247:417-431
33. Kashihara Y, Sakaguchi M, Kuno M (1989) Axonal transport and distribution of endogenous calcitonin gene-related peptide in rat peripheral nerve. J Neurosci 9:3796-3802
34. Kjaer I (1990) Correlated appearance of ossification and nerve tissue in human fetal jaws. J Craniofac Genet Dev Biol 10: 329-336
35. Kontinen YT, Imai S, Suda A (1996) Neuropeptides and the puzzle of bone remodeling: state of the art. Acta Orthop Scand 67:632-639
36. Kruger L, Silverman JD, Mantyh PW, Sternini C, Brecha NC (1989) Peripheral patterns of calcitonin-gene-related peptide general somatic sensory innervation: cutaneous and deep terminations. J Comp Neurol 280:291-302
37. Micevych P E, Kruger L (1992) The status of calcitonin generelated peptide as an effector peptide. Ann N Y Acad Sci 657: 379-396
38. Michelangeli VP (1989) Effects of calcitonin gene-related peptide on cyclic AMP formation in chicken, rat and mouse bone cells. J Bone Min Res 4:269-272
39. 3H-methyl) thymidine incorporation and replication of rat chondrocytes grown in tissue culture plasma, tissue extracts and vasopressin. Endocrinology 100:1365-1375
40. Nilsson J, Euler AM von, Dalsgaard C-J (1985) Stimulation of connective tissue cell growth by substance P and substance K. Nature 315:61-63
41. O'Brien C, Woolf CJ, Fitzgerald M, Lindsay RM, Molander C (1989) Differences in the chemical expression of rat primary afferent neurones which innervate skin, muscle or joint. Neurosci 32:493-502
42. Perry MJ, Lawson SN (1998) Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves. Neuroscience 85:293-310
43. Popken GJ, Farel PB (1997) Sensory neurone number in neonatal and adult rats estimated by means of stereologic and profile-based methods. J Comp Neurol 386:8-15
44. Rahman S, Dobson PR, Bunning RA, Russell RG, Brown BL (1992) The regulation of connective tissue metabolism by vasoactive intestinal polypeptide. Regul Pept 37:111-121
45. Salo PT, Tatton WG (1993) Age-related loss of knee joint afferents in mice. J Neurosci Res 35:664-677
46. Salo PT, Theriault E (1997) Number, distribution and neuropeptide content of rat knee joint afferents. J Anat 190:515-522
47. Shih C, Bernard GW (1997) Calcitonin gene related peptide enhances bone colony development in vitro. Clin Orthop Rel Res 334:335-344
48. Sisask G, Bjurholm A, Ahmed M, Kreicbergs A (1995) Ontogeny of sensory nerves in the developing skeleton. Anat Rec 243:234-240
49. Steiner AL, Parker CW, Kipnis DM (1972) Radioimmunoassay for cyclic nucleotides. J Biol Chem 247:1106-1113
50. Stockwell RA (1971) The ultrastructure of cartilage canals and the surrounding cartilage in the sheep fetus. J Anat 109:397-410
51. Strange-Vognsen HH, Laursen H (1997) Nerves in human epiphyseal uncalcified cartilage. J Pediatr Orthop [B] 6:56-58
52. Strange-Vognsen HH, Arnbjerg J, Hannibal J (1997) Immunocytochemical demonstration of pituitary adenylate cyclase activating polypeptide (PACAP) in the porcine epiphyseal cartilage canals. Neuropeptide 31:137-141
53. Thiebaud D, Akatsu T, Yamashita T, Suda T, Noda T, Martin RE, Fletcher AE, Martin TJ (1991) Structure-activity relationships in calcitonin gene-related peptide: cyclic AMP response in a preosteoblast cell line (KS-4). J Bone Min Res 6:1137-1142
54. Tonra JR, Mendell LM (1998) Effects of postnatal anti-NGF on the development of CGRP-IR neurons in the dorsal root ganglion. J Comp Neurol 392:489-498
55. Trantor IR, Messner HH, Birner R (1995) The effects of neuropeptides (calcitonin gene-related peptide and substance P) on cultivated human pulp cells. J Dent Res 74:1066-1071
56. Vignery A, McCarthy TM (1996) The neuropeptide calcitonin gene related peptide stimulates insulin-like growth factor I production by primary fetal rat osteoblasts. Bone 18:331-335
57. Villablanca A, Murphy CJ, Reid TW (1994) Growth-promoting effects of substance P on endothelial cells in vitro. Circulation Res 75:1113-1120
58. Waschek JA (1996) VIP and PACAP receptor-mediated actions on cell proliferation and survival. Ann N Y Acad Sci 26:290-300
59. Wessels WJ, Feirabend HK, Marani E (1990) Evidence for a rostrocaudal organization in dorsal root ganglia during development as demonstrated by intra-uterine WGA-HRP injections into the hindlimb of rat fetuses. Dev Brain Res 54:273-281
60. Wiesenfeld-Hallin Z, Hökfelt T, Lundberg JM (1984) Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat. Neurosci Lett 23:199-204
61. Wilsman NJ, Van Sickle DC (1974) Cartilage canals, their morphology and distribution. Anat Rec 173:79-94
62. Wimalawansa SJ (1996) Calcitonin gene-related peptide and its receptors: molecular genetics, physiology, pathphysiology and therapeutic potentials. Endocr Rev 17:533-585
63. Wimalawansa SJ (1997) Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily. Crit Rev Neurobiol 11:167-239
64. Woolf CJ (1996) Phenotypic modification of sensory neurones: the role of nerve growth factor in the production of persistent pain. Philos Trans R Soc Lond Biol 351:441-448
65. Zachary I, Woll P J, Rozengurt E (1987) A role for neuropeptides in the control of cell proliferation. Dev Biol 124:259-308
66. Zaidi M, Bevis PJ, Girgis SI, Lynch C, Stevenson JC, MacIntyre I (1985) Circulating CGRP comes from the perivascular nerves. Eur J Pharmacol 117:283-284
67. Zaidi M, Chambers TJ, Bevis PJ, Beacham JL, Gaines Das RE, MacIntyre I (1988) Effects from the calcitonin gene on bone and bone cells. Q J Exp Physiol 73:471-485