Preparation of avidin-labelled gelatin nanoparticles as carriers for biotinylated peptide nucleic acid (PNA)

International Journal of Pharmaceutics

Volumn 196, Issue 2, 2000, Pages 147-149

  Coester, C ^a,b   Kreuter, J ^a   Von Briesen, H ^b   Langer, K ^a  

^a Inst für Pharmazeut Technol   (Germany)

^b INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

Author keywords

Avidin; Covalent linkage; Gelatin; Nanoparticles; Peptide nucleic acid (PNA)

Indexed keywords

AVIDIN; DRUG CARRIER; GELATIN; NANOPARTICLE; PEPTIDE NUCLEIC ACID;

COMPLEX FORMATION; COVALENT BOND; PARTICLE SIZE; PRIORITY JOURNAL; SHORT SURVEY; SURFACE PROPERTY;

EID: 0033976710     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00409-3     Document Type: Article

References (6)

1. Akasaka Y., Ueda H., Takayama K., Machida Y., Nagai T. Preparation and evaluation of bovine serum albumin nanospheres coated with monoclonal antibodies. Drug Des. Deliv. 3(1):1988;85-97.
2. Coester, C., Langer, K., von Briesen, H., Kreuter, J., 1999. Gelatin nanoparticles by two step desolvation - a new preparation method, surface modifications and cell uptake. J. Microencapsulation (accepted).
3. Hanvey J.C., Peffer N.J., Bisi J.E., Thomson S.A., Cadilla R., Josey J.A., Ricca D.J., Hassman C.F., Bonham M.A., Au K.G., Carter S.G., Bruckenstein D.A., Boyd A.L., Noble S.A., Babiss L.E. Antisense and antigene properties of peptide nucleic acids. Science. 258:1992;1481-1485.
4. Molday R.S., Dreyer W.J., Rembaum A., Yen S.P. New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy. J. Cell Biol. 64(1):1975;75-88.
5. Nielsen P.E., Egholm M., Buchardt O. Peptide nucleic acid (PNA). A DNA mimic with a peptide backbone. Bioconj. Chem. 5(1):1994;3-7.
6. Roser M., Kissel T. Surface-modified biodegradable albumin nano- and microspheres. Eur. J. Pharm. Biopharm. 39(1):1993;8-12.