Effect of regional hyperemia on myocardial uptake of 2-deoxy- 2[18F]fluoro-D-glucose

American Journal of Physiology - Endocrinology and Metabolism

Volumn 278, Issue 1 41-1, 2000, Pages

  Mcfalls, Edward O ^a,b   Baldwin, Douglas ^a   Marx, David ^a   Fashingbauer, Peggy ^a   Ward, Herbert B ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b VA MEDICAL CENTER   (United States)

Author keywords

Adenosine; Glucose metabolism; Nitric oxide; Positron emission tomography; Swine; Vasodilatation

Indexed keywords

ADENOSINE; ADENOSINE TRIPHOSPHATE; BRADYKININ; FLUORODEOXYGLUCOSE F 18; GLUCOSE; N(G) METHYLARGININE; NITRIC OXIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HEART MUSCLE BLOOD FLOW; HYPEREMIA; ISOTOPE LABELING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SWINE; VASODILATATION;

EID: 0033976294     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2000.278.1.e96     Document Type: Article

References (27)

1. Angello, D., R. Berne, and N. Coddington. Adenosine and insulin mediate glucose uptake in normoxic rat hearts by different mechanisms. Am. J. Physiol. Heart Circ. Physiol. 265: H880-H885, 1993.
2. Buxton, D., and H. Schelbert. Measurement of regional glucose metabolic rates in reperfused myocardium. Am. J. Physiol. Heart Circ. Physiol. 261: H2058-H2068, 1991.
3. Crane, P., W. Pardridge, L. Braun, and W. Oldendorf. Kinetics of transport and phosphorylation of 2-fluoro-deoxy-D-glucose in rat brain. J. Neurochem. 40: 160-167, 1983.
4. 2-(L-2-phenylisopropyl) adenosine. Circ. Res. 69: 791-799, 1991.
5. Finegan, B., A. Clanachan, C. Coulson, and G. Lopaschuk. Adenosine modification of energy substrate use in isolated hearts perfused with fatty acids. Am. J. Physiol. Heart Circ. Physiol. 262: H1501-H1507, 1992.
6. 18F]2-deoxy-2-fluoro-D-glucose for assessing myocardial glucose uptake. Circulation 91: 2435-2444, 1995.
7. Kirkeboen, K., P. Naess, J. Offstad, and A. Ilebekk. Effects of regional inhibition of nitric oxide sythesis in intact porcine hearts. Am. J. Physiol. Heart Circ. Physiol. 266: H1516-H1527, 1994.
8. Krivokapich, J., H. Sung-Cheng, C. Selin, and M. Phelps. Fluorodeoxyglucose rate constants, lumped constant and glucose metabolic rate in rabbit heart. Am. J. Physiol. Heart Circ. Physiol. 252: H777-H787, 1987.
9. Kuo, L., M. Davis, and W. Chilian. Endothelium-dependent, flow-induced dilatation of isolated coronary arterioles. Am. J. Physiol. Heart Circ. Physiol. 259: H1063-H1070, 1990.
10. Law, W., and M. McLane. Adenosine enhances myocardial glucose uptake only in the presence of insulin. Metabolism 40: 947-952, 1991.
11. Law, W., and R. Raymond. Adenosine potentiates insulin-stimulated myocardial glucose uptake in vivo. Am. J. Physiol. Heart Circ. Physiol. 254: H970-H975, 1988.
12. 14C) deoxyglucose as markers of glycolysis in reperfused myocardium. Circ. Res. 71: 689-700, 1992.
13. Mainwaring, R., R. Lasley, R. Rubio, D. Wyatt, and R. Mentzer, Jr. Adenosine stimulates glucose uptake in the isolated rat heart. Surgery 103: 445-449, 1988.
14. McFalls, E., D. Duncker, R. Krams, L. Sassen, A. Hoogendoorn, and P. Verdouw. Recruitment of myocardial work and metabolism in regionally stunned porcine myocardium. Am. J. Physiol. Heart Circ. Physiol. 263: H1724-H1731, 1992.
15. McFalls, E., D. Duncker, H. Ward, and P. Fashingbauer. Impaired endothelium-dependent vasodilation of coronary resistance vessels in severely stunned porcine myocardium. Basic Res. Cardiol. 90: 498-506, 1995.
16. McFalls, E., H. Ward, P. Fashingbauer, and B. Palmer. Effects of dobutamine stimulation on regional myocardial glucose uptake poststunning as measured by positron emission tomography. Cardiovasc. Res. 28: 1030-1035, 1994.
17. Ng, C., J. Holden, T. DeGrado, D. Raffel, M. Kornguth, and S. Gatley. Sensitivity of myocardial fluorodeoxyglucose lumped constant to glucose and insulin. Am. J. Physiol. Heart Circ. Physiol. 260: H593-H603, 1991.
18. Ratib, O., M. Phelps, and S. Huang. Positron tomography with deoxyglucose for estimating local myocardial glucose metabolism. J. Nucl. Med. 23: 577-586, 1982.
19. Recchia, F., P. McConnell, X. Xu, and T. Hintze. Changes in cardiac metabolism produced by acute inhibition of NO synthase can be reversed by a long-acting NO donor (Abstract). Circulation 98:1212, 1998.
20. Russell, R., III, J. Mrus, J. Mommessin, and H. Taegtmeyer. Compartmentation of hexokinase in rat heart: a critical factor for tracer kinetic analysis of myocardial glucose metabolism. J. Clin. Invest. 90: 1972-1977, 1992.
21. Schneider, C., V. T. Nguyen, and H. Taegtmeyer. Feeding and fasting determine postischemic glucose utilization in isolated working rat hearts. Am. J. Physiol. Heart Circ. Physiol. 260: H542-H548, 1991.
22. Schwaiger, M., R. Neese, L. Araujo, W. Wyns, J. Wisneski, H. Sochor, S. Swank, D. Kulber, C. Selin, M. Phelps, H. Schelbert. Sustained nonoxidative glucose utilization and depletion of glycogen in reperfused canine myocardium. J. Am. Coll. Cardiol. 13: 745-754, 1989.
23. 14C] deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28: 897-916, 1977.
24. Tamaki, N., Y. Yonekura, K. Yamashita, H. Saji, Y. Magata, M. Sends, Y. Konishi, K. Hirata, T. Ban, and J. Konishi. Positron emission tomography using fluorine-18 deoxyglucose in evaluation of coronary artery bypass grafting. Am. J. Cardiol. 64: 860-865, 1989.
25. Tillisch, J., R. Brunken, R. Marshall, M. Schwaiger, M. Mandelkern, M. Phelps, and H. Schelbert. Reversibility of cardiac wall-motion abnormalities predicted by positron tomography. N. Engl. J. Med. 314: 884-888, 1986.
26. 18F]fluoro-deoxy-D-glucose. Am. J. Physiol. Heart Circ. Physiol. 259: H1022-H1031, 1990.
27. 1-adenosine receptors. Am. J. Physiol. Heart Circ. Physiol. 257: H1952-H1957, 1989.