Progressive development of a Th1-Type hepatic cytokine profile in rats with experimental cholangitis

Hepatology

Volumn 31, Issue 2, 2000, Pages 280-290

  Tjandra, Kartika ^a   Sharkey, Keith A ^b   Swain, Mark G ^a,c  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c Departments of Medicine and Community Health Sciences   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLANGITIS; CHOLESTASIS; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DISEASE COURSE; IMMUNOHISTOCHEMISTRY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TH1 CELL;

EID: 0033976032     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510310204     Document Type: Article

References (14)

1. Chapman RW. Role of immune factors in the pathogenesis of primary sclerosing cholangitis. Semin Liver Dis 1991;11:1-4.
2. O'Donohue J, Williams R. Immunological control in primary biliary cirrhosis: the cytokinestory [editorial]. Clin Exp Immunol 1996;105:199-201.
3. Gur H, Shen G, Sutjita M, Terrberry J, Alosachie I, Barka N, Lin HC, et al. Autoantibody profile of primary sclerosing cholangitis. Pathobiology 1995;63:76-82.
4. Chou MJ, Lee SL, Chen TY, Tsay GJ. Specificity of antinuclear antibodies in primary biliary cirrhosis. Ann Rheum Dis 1995;54:148-151.
5. Wiesner RH, LaRusso NF, Ludwig J, Dickson ER. Comparison of the clinicopathologic features of primary sclerosing cholangitis and primary biliary cirrhosis. Gastroenterology 1985;88:108-114.
6. Dienes HP, Lohse AW, Gerken G, Schirmacher P, Gallati H, Lohr HF, Meyer zum Buschenfelde KH. Bile duct epithelia as target cells in primary biliary cirrhosis and primary sclerosing cholangitis. Virchows Arch 1997;431:119-124.
7. Martinez OM, Villanueva JC, Gershwin ME, Krams SM. Cytokine patterns and cytotoxic mediators in primary biliary cirrhosis. HEPATOLOGY 1995;21:113-119.
8. Harada K, Van de Water J, Leung PS, Coppel RL, Ansari A, Nakanuma Y, Gershwin ME. In situ nucleic acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th1 subset. HEPATOLOGY 1997;25:791-796.
9. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more [see comments]. Immunol Today 1996;17:138-146.
10. Sironi M, Breviario F, Proserpio P, Biondi A, Vecchi A, Van Damme J, Dejana E, et al. IL-1 stimulates IL-6 production in endothelial cells. J Immunol 1989;142:549-553.
11. Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-173.
12. Chensue SW, Warmington KS, Ruth J, Lincoln PM, Kunkel SL. Cross-regulatory role of interferon-gamma (IFN-gamma), IL-4 and IL-10 in schistosome egg granuloma formation: in vivo regulation of Th activity and inflammation. Clin Exp Immunol. 1994;98:395-400.
13. Fitch FW, McKisic MD, Lancki DW, Gajewski TF Differential regulation of murine T lymphocyte subsets. Annu Rev Immunol 1993;11:29-48.
14. Lohr HF, Schlaak JF, Gerken G, Fleischer B, Dienes HP, Meyer zum Buschenfelde KH. Phenotypical analysis and cytokine release of liver-infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiology. Liver 1994;14:161-166.