Inhibitory effect of Carum copticum on histamine (H1) receptors of isolated guinea-pig tracheal chains

Journal of Ethnopharmacology

Volumn 69, Issue 3, 2000, Pages 217-227

  Boskabady, M H ^a   Shaikhi, J ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antihistaminic effect; Carum copticum; Guinea pig; Trachea

Indexed keywords

ATROPINE; CHLORPHENIRAMINE; ESSENTIAL OIL; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; INDOMETACIN; PLANT EXTRACT; PROPRANOLOL; SODIUM CHLORIDE;

ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG MECHANISM; EXTRACTION; GUINEA PIG; MALE; MEDICINAL PLANT; MUSCLE RELAXATION; NONHUMAN; PLANT; TRACHEA;

ANIMALS; CHLORPHENIRAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HISTAMINE H1 ANTAGONISTS; MALE; PLANT EXTRACTS; PLANTS, MEDICINAL; RECEPTORS, HISTAMINE H1; TRACHEA;

EID: 0033974907     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(99)00116-6     Document Type: Article

References (16)

1. Ariens E.J. Pharmacology of the airway smooth muscle. Nadel J.A., Pauwels R., Snashall P.D. Bronchial Hyperresponsiveness. 1987;7-23 Blackwell Scientific Publications, London.
2. Arunlakshana O., Schild H.O. Some quantitative use of drug antagonists. Br. J. Pharmacol. 14:1959;48-58.
3. Avesina, A., 1985. Law in Medicine. Sharafkandi, A. (Translator), 2nd edition, vol 2, Soroush Press, Teheran, p 187.
4. Ballba S.I., Hilal S.H., Haggag M.Y. The volatile oil from the herb and fruits of C. copticum at different stages of growth. Planta Med. 23:1973;312-319.
5. Bogats L.N., Epshtein M.M. Effect of a-pinene on the chemoreceptor function of the peripheral nerves. Fiziol-Zhur. Akad. Nauk. Rse. 5:1959;659-661.
6. Boskabady M.H., Moetamedshariati V. Bronchodilatory and anti-cholinergic effects of C. copticum on isolated guinea-pig tracheal chain. Eur. Resp. J. 9(suppl 23):1996;28s.
7. Boskabady M.H., Rakhshandah H., Moetamedshariati V. Bronchodilatory and anti-cholinergic effects of C. copticum on isolated guinea-pig tracheal chains. Med. J. IR Iran. 11:1998;329-334.
8. Buckle D.R., Arch J.R.S., Boering N.E., Foster K.A., Taylor J.F., Taylor S.G., Shaw D.J. Relaxation effect of potassium channel activators BRL 38227 and Pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by Glibenclamide and BRL 31660. Pulm. Pharmacol. 6:1993;77-86.
9. Devansankaraih G., Hanin I., Haranath P.S.R., Ramanaurthy P.S.V. Cholinomimetic effects of aqueous extracts from C. copticum seeds. Br. J. Pharmacol. 52:1972;613-614.
10. Holroyde M.C. The influence of epithelium on the responsiveness of guinea-pig isolated trachea. Br. J. Pharmacol. 87:1986;501-507.
11. Linden A., Bergendal A., Ullman A., Skoogh B.E., Lofdahl C.G. Salmetrol, formetrol, and salbutamol in the isolated guinea-pig trachea: differences in maximum relaxant effect and potency but not in functional antagonism. Thorax. 48:1993;547-553.
12. Linden A., Lofdahl C.G., Ullman A., Skoogh B.E. Non-adrenergic non-cholinergic responses stabilize smooth muscle tone with and without parasympathetic activation in guinea-pig isolated airways. Eur. Resp. J. 6:1993;425-433.
13. Meini S., Ballati L., Evangelista S., Manzini S. Isbufulline, a xanthine derivative, inhibits bronchoconstrictor responses produced by stimulation of capsaicin sensitive nerves in guinea-pig, in vitro and in vivo evidence. Pulm. Pharmacol. 6:1993;279-286.
14. 2+ antagonists on acetylcholine induced contraction in molluscan (Mytilus edulis) smooth muscle. Gen. Pharmacol. 24:1993;1419-1423.
15. 1 blocker chlorpheniramine. J. Allergy Clin. Immunol. 59:1977;54-63.
16. Van Amsterdam R.G.M., Meurs H., Brouwer F., Postema J.B., Timmermans A., Zaagsma J. Role of phosphoinosited metabolism in functional antagonism of airway smooth muscle contraction by beta-adrenoceptor agonist. Eur. J. Pharmacol. 172:1989;175-183.